Reaction Details Report a problem with these data
Target
Cysteinyl leukotriene receptor 1
Ligand
BDBM50286748
Substrate
n/a
Meas. Tech.
ChEBML_99991
Ki
>50000±n/a nM
Citation
 Masamune, H; Breslow, R; Cheng, JB; Conklyn, MJ; Eggler, JF; Marfat, A; Melvin, LS; Pillar, JS; Shirley, JT; Showell, HJ; Tickner, JE Synthesis and in vitro profile of 7-substituted quinoline chromanols as novel, non-acidic LTB4 antagonists Bioorg Med Chem Lett 5:887-892 (1995)    Article 
Target
Name:
Cysteinyl leukotriene receptor 1
Synonyms:
CLTR1_CAVPO | CYSLTR1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39007.58
Organism:
GUINEA PIG
Description:
Leukotriene D4 0 GUINEA PIG::Q2NNR5
Residue:
340
Sequence:
MDETGNPTIPPASNNTCYDSIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLVKTYHEKSAFQVYMINLAVADLLCVCTLPLRVAYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCVAIVFPVQNISLVTQKKARLVCIAIWMFVILTSSPFLMANTYKDEKNNTKCFEPPQDNQAKNYVLILHYVSLFIGFIIPFITIIVCYTMIIFTLLKSSMKKNLSSRKRAIGMIIVVTAAFLVSFMPYHIQRTIHLHFLHNKTKPCDSILRMQKSVVITLSLAASNCCFDPLLYFFSGGNFRRRLSTIRKYSLSSMTYIPKKKTSLPQKGKDICKE
  
Inhibitor
Name:
BDBM50286748
Synonyms:
(3R,4S)-3-Pyridin-2-ylmethyl-7-(1-quinolin-2-yl-ethoxy)-chroman-4-ol | CHEMBL168854
Type:
Small organic molecule
Emp. Form.:
C26H24N2O3
Mol. Mass.:
412.4804
SMILES:
CC(Oc1ccc2[C@@H](O)[C@H](Cc3ccccn3)COc2c1)c1ccc2ccccc2n1
Structure:
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