Reaction Details Report a problem with these data
Target
Lactoylglutathione lyase
Ligand
BDBM50326998
Substrate
n/a
Meas. Tech.
ChEMBL_663474 (CHEMBL1251073)
IC50
16400±n/a nM
Citation
 Takasawa, R; Saeki, K; Tao, A; Yoshimori, A; Uchiro, H; Fujiwara, M; Tanuma, S Delphinidin, a dietary anthocyanidin in berry fruits, inhibits human glyoxalase I. Bioorg Med Chem 18:7029-33 (2010) [PubMed]  Article 
Target
Name:
Lactoylglutathione lyase
Synonyms:
Aldoketomutase | GLO1 | Glx I | Glyoxalase 1 (GLO1) | Glyoxalase I | Ketone-aldehyde mutase | LGUL_HUMAN | Methylglyoxalase | S-D-lactoylglutathione methylglyoxal lyase
Type:
Enzyme
Mol. Mass.:
20772.95
Organism:
Homo sapiens (Human)
Description:
Q04760
Residue:
184
Sequence:
MAEPQPPSGGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQKCDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKMATLM
  
Inhibitor
Name:
BDBM50326998
Synonyms:
CHEMBL591036 | Pelargonidin
Type:
Small organic molecule
Emp. Form.:
C15H11O5
Mol. Mass.:
271.2443
SMILES:
Oc1ccc(cc1)-c1oc2cc(O)cc(=[OH+])c2cc1O
Structure:
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