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Target
D(2) dopamine receptor
Ligand
BDBM50339690
Substrate
n/a
Meas. Tech.
ChEMBL_735243 (CHEMBL1694505)
Ki
54.5±n/a nM
Citation
 Tu, Z; Li, S; Cui, J; Xu, J; Taylor, M; Ho, D; Luedtke, RR; Mach, RH Synthesis and pharmacological evaluation of fluorine-containing D3 dopamine receptor ligands. J Med Chem 54:1555-64 (2011) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50339690
Synonyms:
4-(2-fluoroethyl)-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)benzamide | CHEMBL1688991
Type:
Small organic molecule
Emp. Form.:
C24H32FN3O2
Mol. Mass.:
413.5282
SMILES:
COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(CCF)cc2)CC1
Structure:
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