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Target
Diphosphomevalonate decarboxylase
Ligand
BDBM50287713
Substrate
n/a
Meas. Tech.
ChEMBL_105298 (CHEMBL714140)
Ki
750±n/a nM
Citation
 Vlattas, I; Dellureficio, J; Ku, E; Bohacek, R; Xiaolu, Zhang Inhibition of mevalonate 5-pyrophosphate decarboxylase by a proline-containing transition state analog Bioorg Med Chem Lett 6:2091-2096 (1996)    Article 
Target
Name:
Diphosphomevalonate decarboxylase
Synonyms:
MPD | MVD | MVD1_HUMAN | Mevalonate pyrophosphate decarboxylase
Type:
PROTEIN
Mol. Mass.:
43408.12
Organism:
Homo sapiens (Human)
Description:
ChEMBL_105297
Residue:
400
Sequence:
MASEKPLAAVTCTAPVNIAVIKYWGKRDEELVLPINSSLSVTLHQDQLKTTTTAVISKDFTEDRIWLNGREEDVGQPRLQACLREIRCLARKRRNSRDGDPLPSSLSCKVHVASVNNFPTAAGLASSAAGYACLAYTLARVYGVESDLSEVARRGSGSACRSLYGGFVEWQMGEQADGKDSIARQVAPESHWPELRVLILVVSAEKKLTGSTVGMRASVETSPLLRFRAESVVPARMAEMARCIRERDFPSFAQLTMKDSNQFHATCLDTFPPISYLNAISWRIIHLVHRFNAHHGDTKVAYTFDAGPNAVIFTLDDTVAEFVAAVWHGFPPGSNGDTFLKGLQVRPAPLSAELQAALAMEPTPGGVKYIIVTQVGPGPQILDDPCAHLLGPDGLPKPAA
  
Inhibitor
Name:
BDBM50287713
Synonyms:
[methyl(2-{[(phosphonatooxy)phosphinato]oxy}ethyl)amino]acetate
Type:
Small organic molecule
Emp. Form.:
C5H9NO9P2
Mol. Mass.:
289.076
SMILES:
CN(CCOP([O-])(=O)OP([O-])([O-])=O)CC([O-])=O
Structure:
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