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Target
Cannabinoid receptor 2
Ligand
BDBM50272345
Substrate
n/a
Meas. Tech.
ChEMBL_510484 (CHEMBL1006425)
EC50
1.3±n/a nM
Citation
 Cheng, Y; Albrecht, BK; Brown, J; Buchanan, JL; Buckner, WH; DiMauro, EF; Emkey, R; Fremeau, RT; Harmange, JC; Hoffman, BJ; Huang, L; Huang, M; Lee, JH; Lin, FF; Martin, MW; Nguyen, HQ; Patel, VF; Tomlinson, SA; White, RD; Xia, X; Hitchcock, SA Discovery and optimization of a novel series of N-arylamide oxadiazoles as potent, highly selective and orally bioavailable cannabinoid receptor 2 (CB2) agonists. J Med Chem 51:5019-34 (2008) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CNR2_RAT | Cannabinoid CB2 receptor | Cannabinoid receptor | Cnr2 | rCB2
Type:
Enzyme
Mol. Mass.:
39366.68
Organism:
Rattus norvegicus (Rat)
Description:
Q9QZN9
Residue:
360
Sequence:
MAGCRELELTNGSNGGLEFNPMKEYMILSDAQQIAVAVLCTLMGLLSALENVAVLYLILSSQRLRRKPSYLFIGSLAGADFLASVIFACNFVIFHVFHGVDSRNIFLLKIGSVTMTFTASVGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALGVMWVLSALISYLPLMGWTCCPSPCSELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHQHVASLAEHQDRQVPGIARMRLDVRLAKTLGLVMAVLLICWFPALALMGHSLVTTLSDKVKEAFAFCSMLCLVNSMINPIIYALRSGEIRSAAQHCLTGWKKYLQGLGSEGKEEAPKSSVTETEAEVKTTTGPGSRTPGCSNC
  
Inhibitor
Name:
BDBM50272345
Synonyms:
CHEMBL499059 | N-(2-tert-Butylpyrimidin-5-yl)-3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propanamide
Type:
Small organic molecule
Emp. Form.:
C19H19ClFN5O2
Mol. Mass.:
403.838
SMILES:
CC(C)(C)c1ncc(NC(=O)CCc2nc(no2)-c2ccc(F)cc2Cl)cn1
Structure:
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