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Target
Casein kinase II subunit alpha'
Ligand
BDBM50420550
Substrate
n/a
Meas. Tech.
ChEMBL_841711 (CHEMBL2092254)
IC50
5800±n/a nM
Citation
 Hou, Z; Nakanishi, I; Kinoshita, T; Takei, Y; Yasue, M; Misu, R; Suzuki, Y; Nakamura, S; Kure, T; Ohno, H; Murata, K; Kitaura, K; Hirasawa, A; Tsujimoto, G; Oishi, S; Fujii, N Structure-based design of novel potent protein kinase CK2 (CK2) inhibitors with phenyl-azole scaffolds. J Med Chem 55:2899-903 (2012) [PubMed]  Article 
Target
Name:
Casein kinase II subunit alpha'
Synonyms:
CK2A2 | CSK22_HUMAN | CSNK2A2 | Casein kinase II alpha (prime) | Casein kinase II alpha' | Casein kinase II subunit alpha (CK2A2) | Casein kinase II subunit alpha (CSNK2A2)
Type:
Protein
Mol. Mass.:
41223.82
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
350
Sequence:
MPGPAAGSRARVYAEVNSLRSREYWDYEAHVPSWGNQDDYQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVKKKKIKREVKILENLRGGTNIIKLIDTVKDPVSKTPALVFEYINNTDFKQLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNYDQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYFYPVVKEQSQPCADNAVLSSGLTAAR
  
Inhibitor
Name:
BDBM50420550
Synonyms:
CHEMBL2087009
Type:
Small organic molecule
Emp. Form.:
C14H9N3O3S2
Mol. Mass.:
331.37
SMILES:
OC(=O)c1ccc(cc1)-c1nnc(NC(=O)c2cccs2)s1
Structure:
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