TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:Inhibitory activity of the compound against HIV-1 proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataKi: 0.120nMAssay Description:Inhibitory activity of the compound against HIV-1 proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataKi: 0.190nMAssay Description:Inhibitory activity of the compound against HIV-1 proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataKi: 0.280nMAssay Description:Inhibitory activity of the compound against HIV-1 proteaseMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Inhibition of [3H]-PGE-2 binding to human prostanoid EP4 receptorMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataKi: 0.380nMAssay Description:Inhibitory activity of the compound against HIV-1 proteaseMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 0.680nMAssay Description:Inhibition of [3H]-PGE-2 binding to human prostanoid EP4 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 0.740nMAssay Description:Inhibition of rat prostanoid EP4 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 0.910nMAssay Description:Inhibition of [3H]-PGE-2 binding to human prostanoid EP4 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 5.10nMAssay Description:Inhibition of rat prostanoid EP4 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 5.5nMAssay Description:Inhibition of [3H]-PGE-2 binding to human prostanoid EP4 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 8.40nMAssay Description:Inhibition of [3H]-PGE-2 binding to human prostanoid EP4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Inhibition of recombinant human SphK1 expressed in baculovirus infected sf9 cells using D-erythro-sphingosine as substrate in presence of [gamma-33P]...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 43nMAssay Description:Inhibition of [3H]-PGE-2 binding to human prostanoid EP4 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Inhibition of [3H]-PGE-2 binding to human prostanoid EP4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Inhibition of [3H]-Iloprost binding to human prostanoid IP receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 80nMAssay Description:Inhibition of [3H]-PGE-2 binding to human prostanoid EP4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Inhibition of [3H]-Iloprost binding to human prostanoid IP receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 240nMAssay Description:Inhibition of [3H]-PGE-2 binding to human prostanoid EP4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 610nMAssay Description:Inhibition of [3H]-Iloprost binding to human prostanoid IP receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Inhibtion of [3H]-PGD-2 binding to human prostanoid DP receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-SQ-29,548 binding to human prostanoid TP receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-PGE-2 binding to human prostanoid EP3 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-PGE-2 binding to human prostanoid EP1 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-PGE-2 binding to human prostanoid EP1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-PGF-2 binding to human prostanoid FP receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-SQ-29,548 binding to human prostanoid TP receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-PGE-2 binding to human prostanoid EP2 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-PGE-2 binding to human prostanoid EP3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-PGF-2 binding to human prostanoid FP receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Inhibtion of [3H]-PGD-2 binding to human prostanoid DP receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-SQ-29,548 binding to human prostanoid TP receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Inhibtion of [3H]-PGD-2 binding to human prostanoid DP receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-PGE-2 binding to human prostanoid EP2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-PGF-2 binding to human prostanoid FP receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-Iloprost binding to human prostanoid IP receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 1.02E+3nMAssay Description:Inhibition of [3H]-PGE-2 binding to human prostanoid EP4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:Inhibition of recombinant human SphK2 expressed in baculovirus infected sf9 cells using D-erythro-sphingosine as substrate after 20 mins in presence ...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 2.50E+3nMAssay Description:Inhibition of [3H]-PGE-2 binding to human prostanoid EP1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >3.00E+3nMAssay Description:Inhibition of [3H]-PGF-2 binding to human prostanoid FP receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: >3.00E+3nMAssay Description:Inhibition of [3H]-PGE-2 binding to human prostanoid EP2 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: >3.00E+3nMAssay Description:Inhibition of [3H]-PGE-2 binding to human prostanoid EP2 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: >3.00E+3nMAssay Description:Inhibition of [3H]-PGE-2 binding to human prostanoid EP3 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: >3.00E+3nMAssay Description:Inhibition of [3H]-PGE-2 binding to human prostanoid EP3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >3.00E+3nMAssay Description:Inhibtion of [3H]-PGD-2 binding to human prostanoid DP receptorMore data for this Ligand-Target Pair
Affinity DataKi: >3.00E+3nMAssay Description:Inhibition of [3H]-Iloprost binding to human prostanoid IP receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: >3.00E+3nMAssay Description:Inhibition of [3H]-PGE-2 binding to human prostanoid EP1 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: >3.00E+3nMAssay Description:Inhibition of [3H]-PGE-2 binding to human prostanoid EP2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >3.00E+3nMAssay Description:Inhibition of [3H]-SQ-29,548 binding to human prostanoid TP receptorMore data for this Ligand-Target Pair
Affinity DataKi: >3.00E+3nMAssay Description:Inhibition of [3H]-Iloprost binding to human prostanoid IP receptorMore data for this Ligand-Target Pair