Reaction Details Report a problem with these data
Target
Neuropeptides B/W receptor type 1
Ligand
BDBM50425638
Substrate
n/a
Meas. Tech.
ChEMBL_936637 (CHEMBL2319036)
IC50
610±n/a nM
Citation
 Guerrero, M; Urbano, M; Schaeffer, MT; Brown, S; Rosen, H; Roberts, E SAR analysis of novel non-peptidic NPBWR1 (GPR7) antagonists. Bioorg Med Chem Lett 23:614-9 (2013) [PubMed]  Article 
Target
Name:
Neuropeptides B/W receptor type 1
Synonyms:
GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36111.82
Organism:
Homo sapiens (Human)
Description:
gi_119607128
Residue:
328
Sequence:
MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
  
Inhibitor
Name:
BDBM50425638
Synonyms:
CHEMBL2314297
Type:
Small organic molecule
Emp. Form.:
C22H17ClN2O3
Mol. Mass.:
392.835
SMILES:
COc1cccc(Oc2c(Cl)cnn(Cc3cccc4ccccc34)c2=O)c1
Structure:
Search PDB for entries with ligand similarity: