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Target
N-formyl peptide receptor 3
Ligand
BDBM50435920
Substrate
n/a
Meas. Tech.
ChEMBL_963919 (CHEMBL2393754)
EC50
>50000±n/a nM
Citation
 Giovannoni, MP; Schepetkin, IA; Cilibrizzi, A; Crocetti, L; Khlebnikov, AI; Dahlgren, C; Graziano, A; Dal Piaz, V; Kirpotina, LN; Zerbinati, S; Vergelli, C; Quinn, MT Further studies on 2-arylacetamide pyridazin-3(2H)-ones: design, synthesis and evaluation of 4,6-disubstituted analogs as formyl peptide receptors (FPRs) agonists. Eur J Med Chem 64:512-28 (2013) [PubMed]  Article 
Target
Name:
N-formyl peptide receptor 3
Synonyms:
FML2_HUMAN | FPR3 | FPR3_HUMAN | FPRH1 | FPRL2
Type:
PROTEIN
Mol. Mass.:
39971.00
Organism:
Homo sapiens (Human)
Description:
ChEMBL_580003
Residue:
353
Sequence:
METNFSIPLNETEEVLPEPAGHTVLWIFSLLVHGVTFVFGVLGNGLVIWVAGFRMTRTVNTICYLNLALADFSFSAILPFRMVSVAMREKWPFGSFLCKLVHVMIDINLFVSVYLITIIALDRCICVLHPAWAQNHRTMSLAKRVMTGLWIFTIVLTLPNFIFWTTISTTNGDTYCIFNFAFWGDTAVERLNVFITMAKVFLILHFIIGFSVPMSIITVCYGIIAAKIHRNHMIKSSRPLRVFAAVVASFFICWFPYELIGILMAVWLKEMLLNGKYKIILVLINPTSSLAFFNSCLNPILYVFMGRNFQERLIRSLPTSLERALTEVPDSAQTSNTDTTSASPPEETELQAM
  
Inhibitor
Name:
BDBM50435920
Synonyms:
CHEMBL2391272
Type:
Small organic molecule
Emp. Form.:
C27H24FN3O3
Mol. Mass.:
457.4962
SMILES:
COc1cccc(Cc2cc(nn(CC(=O)Nc3ccc(F)cc3)c2=O)-c2ccc(C)cc2)c1
Structure:
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