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Target
Probable G-protein coupled receptor 142
Ligand
BDBM50440693
Substrate
n/a
Meas. Tech.
ChEMBL_985965 (CHEMBL2432197)
EC50
31±n/a nM
Citation
 Yu, M; Lizarzaburu, M; Motani, A; Fu, Z; Du, X; Liu, JJ; Jiao, X; Lai, S; Fan, P; Fu, A; Liu, Q; Murakoshi, M; Nara, F; Oda, K; Okuyama, R; Reagan, JD; Watanabe, N; Yamazaki, M; Xiong, Y; Zhang, Y; Zhuang, R; Lin, DC; Houze, JB; Medina, JC; Li, L Aminopyrazole-Phenylalanine Based GPR142 Agonists: Discovery of Tool Compound and in Vivo Efficacy Studies. ACS Med Chem Lett 4:829-34 (2013) [PubMed]  Article 
Target
Name:
Probable G-protein coupled receptor 142
Synonyms:
GP142_MOUSE | Gpr142
Type:
PROTEIN
Mol. Mass.:
40779.27
Organism:
Mus musculus
Description:
ChEMBL_985965
Residue:
365
Sequence:
MHLNSNPNSYICDAYQHADLLWSLSPHVLTKAVQPQVTLLPTVNGSNPRYDGVDGHWPESPERSPCVAGIIPVIYYSVLLSLGLPVALARLAARTRKPSYHYLLALTASDIVTQVIIVFVGFLLQGAVLARQVPQAVVRTANILEFAANHASVWIAVLFTVDRYNALCRPLRHRATSSPGRTHRAIAAVIGVTLLTGIPFYWWLDVWRDADPPSTMDKLLKWAHCLIVYFIPCNVFLVTNSAIILRLRKRGQRGLRPLVSKSTAILLGVTSLFALLWAPRIIVMLYHLYVAPVHRDWRVHLALDIANMLAMLNTEVNFGLYCFISKTFRATVRQVICDVHMACALKSQPKQTVVELMLKSVGTEL
  
Inhibitor
Name:
BDBM50440693
Synonyms:
CHEMBL2430983
Type:
Small organic molecule
Emp. Form.:
C20H21N5O3
Mol. Mass.:
379.4124
SMILES:
Cn1nc(cc1NC(=O)[C@H](Cc1ccccc1)NCC(O)=O)-c1ccncc1 |r|
Structure:
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