Reaction Details Report a problem with these data
Target
SGLT1 protein
Ligand
BDBM109279
Substrate
n/a
Meas. Tech.
Inhibition Assay
IC50
14260±0.0 nM
Citation
 Yang, F; Tang, PC; Dong, Q; Tu, W; Fan, J; Guan, D; Shen, G; Wang, Y; Yuan, J; Zhang, L C-aryl glucoside derivatives, preparation process and pharmaceutical use thereof US Patent  US8609622 Publication Date 12/17/2013 
Target
Name:
SGLT1 protein
Synonyms:
Q9QXI6_MOUSE | SGLT1 protein | Sglt1 | Slc5a1 | Solute carrier family 5 (Sodium/glucose cotransporter), member 1 | Uncharacterized protein | sodium-dependent glucose cotransporter 1 (SGLT1)
Type:
Protein
Mol. Mass.:
73320.01
Organism:
Mus musculus (Mouse)
Description:
Q9QXI6
Residue:
665
Sequence:
MDSSTLSPAVTATDAPIPSYERIRNAADISVIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGLAGTGAAAGIAMGGFEWNALVLVVVLGWIFVPIYIKAGVVTMPEYLRKRFGGKRIQIYLSVLSLLLYIFTKISADIFSGAIFINLALGLDIYLAIFILLAITALYTITGGLAAVIYTDTLQTAIMLVGSFILTGFAFNEVGGYEAFMDKYMKAIPTKVSNGNFTAKEECYTPRADSFHIFRDPITGDMPWPGLIFGLAILALWYWCTDQVIVQRCLSAKNMSHVKAGCTLCGYLKLLPMFLMVMPGMISRILYTEKIACVLPEECQKYCGTPVGCTNIAYPTLVVELMPNGLRGLMLSVMMASLMSSLTSIFNSASTLFTMDIYTKIRKKASEKELMIAGRLFILVLIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNEQGAFWGLILGFLIGISRMITEFAYGTGSCMEPSNCPKIICGVHYLYFAIILFVISVITILIISFLTKPIPDVHLYRLCWSLRNSKEERIDLDAGEEEDIPEDSKDTIEIDTEAPQKKKGCFRRAYDLFCGLDQDKGPKMTKEEEEAMKMKMTDTSEKPLWRTVVNINGIILLAVAVFCHAYFA
  
Inhibitor
Name:
BDBM109279
Synonyms:
US8609622, 7
Type:
Small organic molecule
Emp. Form.:
C22H22ClF3O7
Mol. Mass.:
490.854
SMILES:
OC[C@]12COC(O1)([C@H](O)[C@@H](O)[C@@H]2O)c1ccc(Cl)c(Cc2ccc(OCC(F)(F)F)cc2)c1 |r|
Structure:
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