Reaction Details Report a problem with these data
Target
Heme-binding protein HutZ
Ligand
BDBM231681
Substrate
n/a
Meas. Tech.
Heme Binding Assay
pH
6±0
Kd
1.3e+2± 6e+1 nM
Citation
 Uchida, T; Dojun, N; Sekine, Y; Ishimori, K Heme Proximal Hydrogen Bonding between His170 and Asp132 Plays an Essential Role in the Heme Degradation Reaction of HutZ from Vibrio cholerae. Biochemistry 56:2723-2734 (2017) [PubMed]  Article 
Target
Name:
Heme-binding protein HutZ
Synonyms:
Heme-binding protein HutZ (HutZ)
Type:
Protein
Mol. Mass.:
20304.27
Organism:
Vibrio cholerae
Description:
C3LWH1
Residue:
176
Sequence:
MDQQVKQERLQGRLEPEIKEFRQERKTLQLATVDAQGRPNVSYAPFVQNQEGYFVLISHIARHARNLEVNPQVSIMMIEDETEAKQLFARKRLTFDAVASMVERDSELWCQVIAQMGERFGEIIDGLSQLQDFMLFRLQPEHGLFVKGFGQAYQVSGDDLVDFVHLEEGHRKISNG
  
Inhibitor
Name:
BDBM231681
Synonyms:
Hemin
Type:
Small organic molecule
Emp. Form.:
C34H32N4O4
Mol. Mass.:
560.6434
SMILES:
Cc1c(CCC(O)=O)c2cc3[n-]c(cc4nc(cc5[n-]c(cc1n2)c(C)c5C=C)c(C)c4C=C)c(C)c3CCC(O)=O
Structure:
Search PDB for entries with ligand similarity: