Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) for PDB: 3U8D
TargetPhospholipase A2, membrane associated(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM23771(CHEMBL146186 | (3-{[1-benzyl-3-(carbamoylmethyl)-2...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPhospholipase A2, membrane associated(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM23771(CHEMBL146186 | (3-{[1-benzyl-3-(carbamoylmethyl)-2...)
Affinity DataIC50: 470nMpH: 7.5 T: 2°CAssay Description:PLA2 activity is by using the fluorescent phospholipid analogue, beta-pyC-10-PG as the substrate. The increase in fluorescence (ex @342 nm and em@388...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPhospholipase A2, membrane associated(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM23771(CHEMBL146186 | (3-{[1-benzyl-3-(carbamoylmethyl)-2...)
Affinity DataIC50: 470nMAssay Description:Inhibition of human group IIA PLA2 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPhospholipase A2, membrane associated(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM23771(CHEMBL146186 | (3-{[1-benzyl-3-(carbamoylmethyl)-2...)
Affinity DataIC50: 470nMAssay Description:Inhibition of human recombinant group 2A phospholipase A2 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPhospholipase A2, membrane associated(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM23771(CHEMBL146186 | (3-{[1-benzyl-3-(carbamoylmethyl)-2...)
Affinity DataIC50: 3.55E+4nMAssay Description:Inhibitory activity against porcine pancreatic Phospholipase A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPhospholipase A2, membrane associated(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM23771(CHEMBL146186 | (3-{[1-benzyl-3-(carbamoylmethyl)-2...)
Affinity DataIC50: 9.11E+4nMAssay Description:Inhibitory activity against human pancreatic Phospholipase A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)