Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) for PDB: 3UA9
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50007583(CHEMBL562310 | CHEBI:62882)
Affinity DataIC50: 56nMAssay Description:Inhibition of TNKS2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-2(Mouse)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50007583(CHEMBL562310 | CHEBI:62882)
Affinity DataIC50: 56nMAssay Description:Inhibition of TNKS-2 in mouse L-Wnt-STF cells assessed as disruption of Wnt signaling after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50007583(CHEMBL562310 | CHEBI:62882)
Affinity DataIC50: 56nMAssay Description:Inhibition of TNKS2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50007583(CHEMBL562310 | CHEBI:62882)
Affinity DataIC50: 131nMAssay Description:Inhibition of TNKS1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-1(Mouse)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50007583(CHEMBL562310 | CHEBI:62882)
Affinity DataIC50: 131nMAssay Description:Inhibition of TNKS-1 in mouse L-Wnt-STF cells assessed as disruption of Wnt signaling after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50007583(CHEMBL562310 | CHEBI:62882)
Affinity DataIC50: 131nMAssay Description:Inhibition of TNKS1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50007583(CHEMBL562310 | CHEBI:62882)
Affinity DataIC50: 135nMAssay Description:Inhibition of recombinant human TNKS2 ADP-ribosyltransferase domain expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50007583(CHEMBL562310 | CHEBI:62882)
Affinity DataIC50: 135nMAssay Description:Inhibition of recombinant human TNKS2 ADP-ribosyltransferase domain expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)