Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 3WGW
TargetProliferating cell nuclear antigen(Human)
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50431467(CHEMBL2348305)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to full length human PCNA expressed in Escherichia coli BL21(DE3) assessed as inhibition of interaction with N-terminal 5-carboxyflu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProliferating cell nuclear antigen(Human)
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50431467(CHEMBL2348305)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProliferating cell nuclear antigen(Human)
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50431467(CHEMBL2348305)
Affinity DataIC50: 2.00E+4nMAssay Description:Binding affinity to monoubiquitinated PCNA derived from human GM04312 cells assessed as inhibition of interaction with His8-tagged DNA polymerase eta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)