Affinity DataKd: 2.50E+3nMAssay Description:Equilibrium dissociation constant against recombinant Dopamine receptor D1A expressed in COS7 cellsMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataEC50: 20nMAssay Description:Agonist activity at human D1 receptor assessed as cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 37nMAssay Description:Agonist activity at human dopamine D1 receptor expressed in HEK293 cells assessed as cAMP accumulation after 15 minsMore data for this Ligand-Target Pair
Affinity DataEC50: 2.60nMAssay Description:Agonist activity at human dopamine D1 receptor expressed in HEK-T cells assessed as cAMP production incubated for 15 mins by luciferase based Glosens...More data for this Ligand-Target Pair
Affinity DataEC50: 44nMAssay Description:Agonist activity at wild type human D1R expressed in HEK293 cells assessed as effect on cAMP accumulation incubated for 10 mins by Gs-cAMP Glosensor ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.40E+3nMAssay Description:Agonist activity at wild type human D1R expressed in HEK293 cells assessed as effect on beta-arrestin2 recruitment by PRESTO-Tango beta-arrestin2 rec...More data for this Ligand-Target Pair
Affinity DataEC50: 5.00E+3nMAssay Description:Effective concentration was determined for the adenylate cyclase activity in rat striatal tissue as a measure of Dopamine receptor D1 functional acti...More data for this Ligand-Target Pair
Affinity DataEC50: 232nMAssay Description:Agonist activity at human dopamine D1 receptor expressed in HEK293T cells assessed as induction of cAMP levels after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Adenylate cyclase assay carried out in LTK cells transfected with human Dopamine receptor D1More data for this Ligand-Target Pair
Affinity DataEC50: 3.50E+3nMAssay Description:Dopamine receptor D1 agonist efficacy was measured with stimulation of dopamine-sensitive rat adenylate cyclase in caudate membranes. Partial agonist...More data for this Ligand-Target Pair
Affinity DataEC50: 120nMAssay Description:Activity at human dopamine D1 receptor expressed in HEK293 cells assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
Affinity DataEC50: 35nMAssay Description:Agonist activity at human recombinant dopamine D1 receptor expressed in CHO cells assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration half-maximal displacement of 1.0 nM [3H]NPA specific binding from rat striatal membranes using 10e-5 (+/-)ADTNMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibitory concentration for half-maximal displacement of 1.0 nM [3H]ADTN specific binding from rat striatal membranes using 10E-5 sulpirideMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Tested for binding to dopamine receptor using [3H]- ADTN as radioligand in calf caudate nucleus homogenates.More data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Tested for binding to dopamine receptor using [3H]apomorphine as radioligand in calf caudate nucleus homogenates.More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:The IC50 value was reported as apparent, since [3H]NCA was purported to be irreversible. Result indicates the mean of two separate experiments, each ...More data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:Inhibition of [3H]dopamine binding to Dopamine receptor in calf caudate nuclei.More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:In vitro binding affinity towards Dopamine D1 receptor using [3H]-SCH- 23390 as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 510nMAssay Description:Inhibitory binding activity against dopamine receptor using [3H]ADTN as the radioligand in striatal tissue of calf brain.More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Displacement of [3H]- #NAME from binding Dopamine receptor D1 in rat striatumMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of [3H]haloperidol binding to Dopamine receptor in calf caudate nuclei.More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Compound was evaluated for the inhibition of [3H]-SCH- 23390 binding to Dopamine receptor D1 of rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibitory activity against [3H]-SCH- 23390 in Rat Striatal membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 5.34E+3nMAssay Description:Tested for Dopamine receptor activity by the inhibition against spiroperidol binding to rat caudate tissue.More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Tested for binding to dopamine receptor using [3H]spiroperidol as radioligand in calf caudate nucleus homogenates.More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibitory binding activity against dopamine receptor using [3H]spiperone as the radioligand in striatal tissue of calf brain.More data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Binding Affinity was tested on High Affinity Site of Bovine Dopamine receptor D1. Tested for ability to displace the radioligand [3H]-SCH- 23390More data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:Binding Affinity was tested on relative proportion of High Affinity Site of Bovine dopamine receptor D1. Tested for ability to displace the radioliga...More data for this Ligand-Target Pair
Affinity DataKi: 124nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor expressed in Ltk deficient fibroblast cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Binding affinity against cloned human Dopamine receptor D1 using [125I]-SCH 23982 as radioligand transfected in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Compound was tested for binding affinity against dDopamine receptor D1 using [3H]fenoldopam as a radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 192nMAssay Description:Binding affinity to displace [3H]- SCH 23390 against Dopamine receptor D1More data for this Ligand-Target Pair
Affinity DataKi: 243nMAssay Description:Displacement of [3H]-SCH23390 from human dopamine D1 receptor expressed in LTK cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 309nMAssay Description:Binding affinity against Dopamine receptor D1 in rat striatal membranes using [3H]SCH-23390More data for this Ligand-Target Pair
Affinity DataKi: 417nMAssay Description:Binding Affinity was determined against Dopamine receptor D1 in rat striatal membranes using [3H]- SCH 23390 radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 440nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor in bovine striatumMore data for this Ligand-Target Pair
Affinity DataKi: 650nMAssay Description:Binding Affinity was tested on low Affinity Site of Bovine Dopamine D1 Receptor. Tested for ability to displace the radioligand [3H]-SCH- 23390 at th...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity at Dopamine receptor D1 in rat neostriatum by [3H]-SCH- 23390 displacement.More data for this Ligand-Target Pair
Affinity DataKi: 1.60E+3nMAssay Description:Binding Affinity was determined for its ability to displace the radioligand [3H]-SCH- 23390 from Bovine dopamine receptor D1More data for this Ligand-Target Pair
Affinity DataKi: 4.30E+3nMAssay Description:Binding affinity for dopamine D1-like receptor labelled with [3H]SCH-23390 in retinaMore data for this Ligand-Target Pair
