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TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM408867(US10376531, Compound 27 | US10813942, Compound 27)
Affinity DataKd:  700nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
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TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM408867(US10376531, Compound 27 | US10813942, Compound 27)
Affinity DataKd:  1.10E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2021
Entry Details
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TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM408863(US10376531, Compound 24 | US10813942, Compound 24)
Affinity DataKd:  1.10E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
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TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM408868(US10376531, Compound 28 | US10813942, Compound 28)
Affinity DataKd:  1.20E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
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TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM408863(US10376531, Compound 24 | US10813942, Compound 24)
Affinity DataKd:  1.40E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2021
Entry Details
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TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM408868(US10376531, Compound 28 | US10813942, Compound 28)
Affinity DataKd:  2.00E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2021
Entry Details
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TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM408858(US10376531, Compound 20 | US10813942, Compound 20)
Affinity DataKd:  2.18E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
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TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM408862(US10376531, Compound 25 | US10813942, Compound 25)
Affinity DataKd:  2.20E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
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TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM408860(US10376531, Compound 21 | US10813942, Compound 21)
Affinity DataKd:  2.60E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2021
Entry Details
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TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM408856(US10376531, Compound 18 | US10813942, Compound 18)
Affinity DataKd:  3.00E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2021
Entry Details
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TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM408862(US10376531, Compound 25 | US10813942, Compound 25)
Affinity DataKd:  3.10E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2021
Entry Details
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TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM408856(US10376531, Compound 18 | US10813942, Compound 18)
Affinity DataKd:  3.10E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
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TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM408859(US10376531, Compound 19 | US10813942, Compound 19)
Affinity DataKd:  3.30E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
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TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM408860(US10376531, Compound 21 | US10813942, Compound 21)
Affinity DataKd:  3.40E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
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TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM408858(US10376531, Compound 20 | US10813942, Compound 20)
Affinity DataKd:  3.40E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2021
Entry Details
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TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM408857(US10376531, Compound 17 | US10813942, Compound 17)
Affinity DataKd:  3.80E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2021
Entry Details
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TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM408859(US10376531, Compound 19 | US10813942, Compound 19)
Affinity DataKd:  4.70E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2021
Entry Details
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TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM408857(US10376531, Compound 17 | US10813942, Compound 17)
Affinity DataKd:  5.30E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
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TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM408861(US10376531, Compound 22 | US10813942, Compound 22)
Affinity DataKd:  5.50E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
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TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM408861(US10376531, Compound 22 | US10813942, Compound 22)
Affinity DataKd:  6.50E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2021
Entry Details
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TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM408865(US10376531, Compound 29 | US10813942, Compound 29)
Affinity DataKd:  6.90E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
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TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM408853(US10376531, Compound 3 | US10813942, Compound 3)
Affinity DataKd:  7.18E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2021
Entry Details
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PDB3D3D Structure (crystal)
TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM408853(US10376531, Compound 3 | US10813942, Compound 3)
Affinity DataKd:  7.18E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
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PDB3D3D Structure (crystal)
TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM408855(US10376531, Compound 1 | US10813942, Compound 1)
Affinity DataKd:  9.00E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2021
Entry Details
Go to US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM408855(US10376531, Compound 1 | US10813942, Compound 1)
Affinity DataKd:  9.00E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
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TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM656245(US20240072809, Compound A333)
Affinity DataKd: >1.00E+4nMAssay Description:The dissociation constants (KD) of compounds described herein to the ASGP receptor are measured in SPR experiments using a Biacore 8K instrument (GE ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
Go to US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM656277(US20240072809, Compound A370)
Affinity DataKd: >1.00E+4nMAssay Description:The dissociation constants (KD) of compounds described herein to the ASGP receptor are measured in SPR experiments using a Biacore 8K instrument (GE ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
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TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM408865(US10376531, Compound 29 | US10813942, Compound 29)
Affinity DataKd:  1.02E+4nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2021
Entry Details
Go to US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM408869(US10376531, Compound 31 | US10813942, Compound 31)
Affinity DataKd:  1.23E+4nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
Go to US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM408869(US10376531, Compound 31 | US10813942, Compound 31)
Affinity DataKd:  1.37E+4nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2021
Entry Details
Go to US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM656268(US20240072809, Compound A361)
Affinity DataKd: >2.00E+4nMAssay Description:The dissociation constants (KD) of compounds described herein to the ASGP receptor are measured in SPR experiments using a Biacore 8K instrument (GE ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
Go to US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM656264(US20240072809, Compound A356)
Affinity DataKd: >2.00E+4nMAssay Description:The dissociation constants (KD) of compounds described herein to the ASGP receptor are measured in SPR experiments using a Biacore 8K instrument (GE ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
Go to US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM656276(US20240072809, Compound A369)
Affinity DataKd: >2.00E+4nMAssay Description:The dissociation constants (KD) of compounds described herein to the ASGP receptor are measured in SPR experiments using a Biacore 8K instrument (GE ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
Go to US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM656275(US20240072809, Compound A368)
Affinity DataKd: >2.00E+4nMAssay Description:The dissociation constants (KD) of compounds described herein to the ASGP receptor are measured in SPR experiments using a Biacore 8K instrument (GE ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
Go to US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM656272(US20240072809, Compound A365)
Affinity DataKd: >2.00E+4nMAssay Description:The dissociation constants (KD) of compounds described herein to the ASGP receptor are measured in SPR experiments using a Biacore 8K instrument (GE ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
Go to US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM656189(US20240072809, Compound A157)
Affinity DataKd: >2.00E+4nMAssay Description:The dissociation constants (KD) of compounds described herein to the ASGP receptor are measured in SPR experiments using a Biacore 8K instrument (GE ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
Go to US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM656187(US20240072809, Compound A149)
Affinity DataKd: >2.00E+4nMAssay Description:The dissociation constants (KD) of compounds described herein to the ASGP receptor are measured in SPR experiments using a Biacore 8K instrument (GE ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
Go to US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM656186(US20240072809, Compound A148)
Affinity DataKd: >2.00E+4nMAssay Description:The dissociation constants (KD) of compounds described herein to the ASGP receptor are measured in SPR experiments using a Biacore 8K instrument (GE ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
Go to US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM656260(US20240072809, Compound A351)
Affinity DataKd: >2.00E+4nMAssay Description:The dissociation constants (KD) of compounds described herein to the ASGP receptor are measured in SPR experiments using a Biacore 8K instrument (GE ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
Go to US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM656259(US20240072809, Compound A350)
Affinity DataKd: >2.00E+4nMAssay Description:The dissociation constants (KD) of compounds described herein to the ASGP receptor are measured in SPR experiments using a Biacore 8K instrument (GE ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
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TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM656261(US20240072809, Compound A352)
Affinity DataKd: >2.00E+4nMAssay Description:The dissociation constants (KD) of compounds described herein to the ASGP receptor are measured in SPR experiments using a Biacore 8K instrument (GE ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
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TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM656257(US20240072809, Compound A348)
Affinity DataKd: >2.00E+4nMAssay Description:The dissociation constants (KD) of compounds described herein to the ASGP receptor are measured in SPR experiments using a Biacore 8K instrument (GE ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
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TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM656235(US20240072809, Compound A322)
Affinity DataKd: >2.00E+4nMAssay Description:The dissociation constants (KD) of compounds described herein to the ASGP receptor are measured in SPR experiments using a Biacore 8K instrument (GE ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
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TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM656241(US20240072809, Compound A328)
Affinity DataKd: >2.00E+4nMAssay Description:The dissociation constants (KD) of compounds described herein to the ASGP receptor are measured in SPR experiments using a Biacore 8K instrument (GE ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
Go to US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM656305(US20240072809, Compound A403)
Affinity DataKd: >2.00E+4nMAssay Description:The dissociation constants (KD) of compounds described herein to the ASGP receptor are measured in SPR experiments using a Biacore 8K instrument (GE ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
Go to US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM656221(US20240072809, Compound A308)
Affinity DataKd: >2.00E+4nMAssay Description:The dissociation constants (KD) of compounds described herein to the ASGP receptor are measured in SPR experiments using a Biacore 8K instrument (GE ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
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TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM656279(US20240072809, Compound A372)
Affinity DataKd: >2.00E+4nMAssay Description:The dissociation constants (KD) of compounds described herein to the ASGP receptor are measured in SPR experiments using a Biacore 8K instrument (GE ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
Go to US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM656218(US20240072809, Compound A305)
Affinity DataKd: >2.00E+4nMAssay Description:The dissociation constants (KD) of compounds described herein to the ASGP receptor are measured in SPR experiments using a Biacore 8K instrument (GE ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
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TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM656281(US20240072809, Compound A374)
Affinity DataKd: >2.00E+4nMAssay Description:The dissociation constants (KD) of compounds described herein to the ASGP receptor are measured in SPR experiments using a Biacore 8K instrument (GE ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
Go to US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM656292(US20240072809, Compound A387)
Affinity DataKd: >2.00E+4nMAssay Description:The dissociation constants (KD) of compounds described herein to the ASGP receptor are measured in SPR experiments using a Biacore 8K instrument (GE ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
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