TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataEC50: 0.00400nMAssay Description:Agonist activity at recombinant human V1a receptor expressed in HEK293 cells assessed as increase in intracellular calcium level measured at 3 secs i...More data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.0320nMAssay Description:Inhibition of human vasopressin V1a receptor expressed in CHO cells by polarisation binding assay using 384-well plate membranesMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataEC50: 0.0340nMAssay Description:Agonist activity at human V1b receptor expressed in CHO cells assessed as calcium mobilization measured after 30 mins by Fluo-4-AM dye based FLIPR as...More data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.0360nMAssay Description:Inhibition of human vasopressin V1a receptor expressed in CHO cells by polarisation binding assay using 96-well plate membranesMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.0372nMAssay Description:Displacement of [3H]AVP from human V1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.0398nMAssay Description:Displacement of [3H]AVP from human V1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.0500nMAssay Description:Displacement [3H]Arg human recombinant Vasopressin V1a receptorMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.0600nMAssay Description:Displacement [3H]Arg human recombinant Vasopressin V1a receptorMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.0630nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.0700nMAssay Description:Displacement of [125I]- HO-LVA from human Vasopressin V1a receptor in membranes of CHO cellsMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.0800nMAssay Description:Displacement of [125I]- HO-LVA from human Vasopressin V1a receptor in membranes of CHO cellsMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.0900nMAssay Description:Displacement of [3H]AVP from human vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.0955nMAssay Description:Displacement of [3H]AVP from human V1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:Displacement of [3H]vasopressin from human V1A receptor assessed as inhibition constant by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:Displacement [3H]Arg human recombinant Vasopressin V1a receptorMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:Displacement of [3H]vasopressin from human V1A receptor assessed as inhibition constant by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:Displacement of [3H]vasopressin from human V1A receptor assessed as inhibition constant by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataEC50: 0.120nMAssay Description:Agonist activity at human V1a receptor expressed in CHO cells assessed as calcium mobilization measured after 30 mins by Fluo-4-AM dye based FLIPR as...More data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataEC50: 0.126nMAssay Description:Antagonist activity at human vasopressin 1a receptor expressed in HEK293 cell membranes assessed as inhibition of AVP-induced increase in Ca2+ flux p...More data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataEC50: 0.126nMAssay Description:Antagonist activity at human vasopressin 1a receptor expressed in HEK293 cell membranes assessed as inhibition of AVP-induced increase in Ca2+ flux p...More data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataEC50: 0.140nMAssay Description:Agonist activity at recombinant human vasopressin V1a receptor expressed in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataEC50: 0.155nMAssay Description:Agonist activity at recombinant human vasopressin V1a receptor expressed in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataEC50: 0.158nMAssay Description:Antagonist activity at human vasopressin 1a receptor expressed in HEK293 cell membranes assessed as inhibition of AVP-induced increase in Ca2+ flux p...More data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataEC50: 0.158nMAssay Description:Antagonist activity at human vasopressin 1a receptor expressed in HEK293 cell membranes assessed as inhibition of AVP-induced increase in Ca2+ flux p...More data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.170nMAssay Description:Displacement of [125I]- HO-LVA from human Vasopressin V1a receptor in membranes of CHO cellsMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.170nMAssay Description:Displacement of [125I]- HO-LVA from human Vasopressin V1a receptor in membranes of CHO cellsMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataEC50: 0.170nMAssay Description:Agonist activity at human V1b receptor expressed in CHO cells assessed as calcium mobilization measured after 30 mins by Fluo-4-AM dye based FLIPR as...More data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataEC50: 0.180nMAssay Description:Agonist activity at human V1A receptor expressed in HEK293 cells assessed as intracellular calcium level measured at 3 secs interval for 5 mins by fu...More data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.182nMAssay Description:Displacement of [3H]AVP from human V1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.190nMAssay Description:Inhibition of human vasopressin V1a receptor expressed in COS7 cells by HTRF-FRET assay using 96-well plate membranesMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataEC50: 0.190nMAssay Description:Agonist activity at recombinant human V1a receptor expressed in HEK293 cells assessed as increase in intracellular calcium level measured at 3 secs i...More data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]vasopressin from human V1A receptor assessed as inhibition constant by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]vasopressin from human V1A receptor assessed as inhibition constant by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]vasopressin from human V1A receptor assessed as inhibition constant by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]vasopressin from human V1A receptor assessed as inhibition constant by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [Se-Se]-AVP from human V1A receptor expressed in CHO cells after 4 hrs by RP-LC-ICPMS analysisMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]vasopressin from human V1A receptor assessed as inhibition constant by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]vasopressin from human V1A receptor assessed as inhibition constant by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]vasopressin from human V1A receptor assessed as inhibition constant by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]vasopressin from human V1A receptor assessed as inhibition constant by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.209nMAssay Description:Displacement of [3H]AVP from human V1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.209nMAssay Description:Displacement of [3H]AVP from human V1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataEC50: 0.210nMAssay Description:Agonist activity at recombinant human vasopressin V1a receptor expressed in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.210nMAssay Description:Inhibition of human vasopressin V1a receptor expressed in COS7 cells by HTRF-FRET assay using 96-well plate membranesMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.210nMAssay Description:Inhibition of human vasopressin V1a receptor expressed in COS7 cells by HTRF-FRET assay using 384-well plate membranesMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.230nMAssay Description:Displacement of [125I]- HO-LVA from human Vasopressin V1a receptor in membranes of CHO cellsMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataEC50: 0.234nMAssay Description:Agonist activity at recombinant human vasopressin V1a receptor expressed in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetVasopressin V1a receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.234nMAssay Description:Displacement of [3H]AVP from human V1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair











































