Compile Data Set for Download or QSAR
Report error Found 1853 for UniProtKB: P46098
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Human)
University of Caen Normandy

Curated by ChEMBL
LigandPNGBDBM50058283(6-(4-Benzyl-piperazin-1-yl)-pyrido[3,2-e]pyrrolo[1...)
Affinity DataIC50: 0.000813nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Human)
University of Caen Normandy

Curated by ChEMBL
LigandPNGBDBM50408165(CHEMBL299231)
Affinity DataIC50: 0.00398nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50417287(Aloxi | Aurothioglucose | PALONOSETRON | PALONOSET...)
Affinity DataKi:  0.0316nMAssay Description:Binding affinity to 5HT3A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50459886(CHEMBL261010)
Affinity DataKi:  0.0400nMAssay Description:Displacement of [3H]granisetron from human 5-HT3A receptor expressed in HEK293 cells by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50397290(VUF-10147 | CHEMBL475331)
Affinity DataKi:  0.0513nMAssay Description:Displacement of [3H]granisetron from 5HT3A receptor expressed in HEK293 cells after 24 hrs by scintillation counting in presence of quipazineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50334454(Ramosetron | CHEMBL1643895 | US9045501, Ramosetron)
Affinity DataKi:  0.0600nMAssay Description:Binding affinity to human 5HT3A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50334454(Ramosetron | CHEMBL1643895 | US9045501, Ramosetron)
Affinity DataKi:  0.0600nM ΔG°:  -58.3kJ/molepH: 7.5 T: 2°CAssay Description:The relative affinity of the various compounds for the human 5-HT3 receptor was measured in a radioligand binding assay, using a scintillation proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Human)
University of Caen Normandy

Curated by ChEMBL
LigandPNGBDBM50408166(CHEMBL416662)
Affinity DataIC50: 0.0813nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM85330(NSC_68647 | CAS_68647 | ONDANSETRON | Ondansetron ...)
Affinity DataIC50: 0.0900nMAssay Description:Antagonist activity at human 5HT3A receptor expressed in xenopus oocytes assessed as inhibition of 5HT-induced effect by electrophysiological methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50214492(CHEMBL145725 | RS-16566)
Affinity DataKi:  0.145nMAssay Description:Binding affinity for 5-hydroxytryptamine 3 receptor by displacement of [3H](R)-zacopride from ondansetron-treated NG-108-15 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2018
Entry Details

Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50307815(4-Hydroxy-1-methyl-N-[(3-endo)-9-methyl-9-azabicyc...)
Affinity DataKi:  0.170nMAssay Description:Displacement of [3H]granisetron from human 5HT3A receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM221600(US9303045, 87 | US9695195, 87)
Affinity DataIC50: 0.180nMT: 2°CAssay Description:The 5HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 3A/3B(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50417287(Aloxi | Aurothioglucose | PALONOSETRON | PALONOSET...)
Affinity DataKd:  0.180nMAssay Description:Binding affinity to human wild type 5-HT3A/5-HT3B receptor expressed in HEK293 cells after 24 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM221600(US9303045, 87 | US9695195, 87)
Affinity DataIC50: 0.180nMT: 2°CAssay Description:The 5HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50056419(ZACOPRIDE,R | 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3...)
Affinity DataKi:  0.182nMAssay Description:Binding affinity for 5-hydroxytryptamine 3 receptor by displacement of [3H]-BRL 43694 from NG-108-15 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2018
Entry Details

Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM221544(US9303045, 30 | US9695195, 30)
Affinity DataIC50: 0.200nMT: 2°CAssay Description:The 5HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50014549(CHEMBL3261480 | US9045501, 4)
Affinity DataKi:  0.200nM ΔG°:  -55.4kJ/molepH: 7.5 T: 2°CAssay Description:The relative affinity of the various compounds for the human 5-HT3 receptor was measured in a radioligand binding assay, using a scintillation proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50014549(CHEMBL3261480 | US9045501, 4)
Affinity DataKi:  0.200nMAssay Description:Displacement of [9-methyl-3H]BRL-43694 from human 5-HT3A receptor after overnight incubation by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM221544(US9303045, 30 | US9695195, 30)
Affinity DataIC50: 0.200nMT: 2°CAssay Description:The 5HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 3A/3B(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50443668(CHEBI:5537 | CHEMBL1290003 | GRANISETRON)
Affinity DataKd:  0.200nMAssay Description:Binding affinity to human wild type 5-HT3A/5-HT3B receptor expressed in HEK293 cells after 24 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM221601(US9303045, 88 | US9695195, 88)
Affinity DataIC50: 0.220nMT: 2°CAssay Description:The 5HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM221592(US9303045, 127 | US9303045, 79 | US9695195, 127)
Affinity DataIC50: 0.220nMT: 2°CAssay Description:The 5HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM221601(US9303045, 88 | US9695195, 88)
Affinity DataIC50: 0.220nMT: 2°CAssay Description:The 5HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM221592(US9303045, 127 | US9303045, 79 | US9695195, 127)
Affinity DataIC50: 0.220nMT: 2°CAssay Description:The 5HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50307826(1-Methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]n...)
Affinity DataKi:  0.230nMAssay Description:Displacement of [3H]granisetron from human 5HT3A receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM221622(US9303045, 113 | US9695195, 113)
Affinity DataIC50: 0.230nMT: 2°CAssay Description:The 5HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM221622(US9303045, 113 | US9695195, 113)
Affinity DataIC50: 0.230nMT: 2°CAssay Description:The 5HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM221572(US9303045, 58 | US9695195, 58)
Affinity DataIC50: 0.240nMT: 2°CAssay Description:The 5HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM221572(US9303045, 58 | US9695195, 58)
Affinity DataIC50: 0.240nMT: 2°CAssay Description:The 5HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM221624(US9303045, 123 | US9303045, 117 | US9695195, 123)
Affinity DataIC50: 0.280nMT: 2°CAssay Description:The 5HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM221624(US9303045, 123 | US9303045, 117 | US9695195, 123)
Affinity DataIC50: 0.280nMT: 2°CAssay Description:The 5HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Human)
University of Caen Normandy

Curated by ChEMBL
LigandPNGBDBM50408162(CHEMBL299634)
Affinity DataIC50: 0.288nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM221610(US9303045, 99 | US9695195, 99)
Affinity DataIC50: 0.290nMT: 2°CAssay Description:The 5HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM221610(US9303045, 99 | US9695195, 99)
Affinity DataIC50: 0.290nMT: 2°CAssay Description:The 5HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM221654(US9303045, 159 | US9695195, 159)
Affinity DataIC50: 0.298nMT: 2°CAssay Description:The 5HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM221654(US9303045, 159 | US9695195, 159)
Affinity DataIC50: 0.300nMT: 2°CAssay Description:The 5HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50417287(Aloxi | Aurothioglucose | PALONOSETRON | PALONOSET...)
Affinity DataKd:  0.320nMAssay Description:Binding affinity to human wild type 5-HT3A receptor expressed in HEK293 cells after 24 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM221651(US9303045, 154 | US9695195, 154)
Affinity DataIC50: 0.328nMT: 2°CAssay Description:The 5HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM221651(US9303045, 154 | US9695195, 154)
Affinity DataIC50: 0.330nMT: 2°CAssay Description:The 5HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM221561(US9303045, 47 | US9695195, 47)
Affinity DataIC50: 0.330nMT: 2°CAssay Description:The 5HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50110300(N-(4-(3-(piperidin-1-yl)propoxy)phenethyl)-5,6,7,8...)
Affinity DataKi:  0.330nMAssay Description:Binding affinity to 5HT3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM221561(US9303045, 47 | US9695195, 47)
Affinity DataIC50: 0.330nMT: 2°CAssay Description:The 5HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Human)
University of Caen Normandy

Curated by ChEMBL
LigandPNGBDBM50408167(CHEMBL53416)
Affinity DataIC50: 0.355nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50103072(1-Benzyl-2-piperazin-1-yl-1H-benzoimidazole | Leri...)
Affinity DataKi:  0.360nMAssay Description:Binding affinity against human 5-hydroxytryptamine 3A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50000492(ZACOPRIDE,R | 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3...)
Affinity DataKi:  0.390nMAssay Description:Displacement of [3H]GR65630 from 5-HT3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM221627(US9303045, 120 | US9695195, 120)
Affinity DataIC50: 0.390nMT: 2°CAssay Description:The 5HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM221624(US9303045, 123 | US9303045, 117 | US9695195, 123)
Affinity DataIC50: 0.390nMT: 2°CAssay Description:The 5HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM221627(US9303045, 120 | US9695195, 120)
Affinity DataIC50: 0.390nMT: 2°CAssay Description:The 5HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM221624(US9303045, 123 | US9303045, 117 | US9695195, 123)
Affinity DataIC50: 0.390nMT: 2°CAssay Description:The 5HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 3A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50000492(ZACOPRIDE,R | 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3...)
Affinity DataKi:  0.398nMAssay Description:Displacement of [3H]GR65630 from 5-HT3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
Displayed 1 to 50 (of 1853 total ) | Next | Last >>
Jump to: