Compile Data Set for Download or QSAR
Report error Found 109 of affinity data for UniProtKB/TrEMBL: Q6LC90
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50059333BDBM50059333((R)-2-({5-[2-(2-Amino-4-oxo-4,6,7,8-tetrahydro-3H-...)
Affinity DataKd:  0.000500nMAssay Description:compound was tested for the ability to function as transport substrates for the human folate-binding protein(mFBP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50059339BDBM50059339(2-{4-[2-(2-Amino-4-oxo-4,6,7,8-tetrahydro-3H-pyrim...)
Affinity DataKd:  0.00200nMAssay Description:compound was tested for the ability to function as transport substrates for the human folate-binding protein(mFBP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50059335BDBM50059335((S)-2-({5-[2-(2-Amino-4-oxo-4,6,7,8-tetrahydro-3H-...)
Affinity DataKd:  0.00320nMAssay Description:compound was tested for the ability to function as transport substrates for the human folate-binding protein(mFBP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50503240BDBM50503240(CHEMBL4445651)
Affinity DataIC50: 0.140nMAssay Description:Binding affinity to human FRalpha expressed in Chinese hamster RT16 cells assessed as antiproliferative activity measured as reduction in cell growth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50059334BDBM50059334((S)-2-({5-[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimi...)
Affinity DataKd:  0.153nMAssay Description:compound was tested for the ability to function as transport substrates for the human folate-binding protein(mFBP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50354833BDBM50354833(CHEMBL1834488 | AGF94)
Affinity DataIC50: 0.310nMAssay Description:Inhibition of FRalpha (unknown origin) expressed in Chinese hamster RT16 cells assessed as cell growth inhibition incubated up to 96 hrs by Celltiter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50354833BDBM50354833(CHEMBL1834488 | AGF94)
Affinity DataIC50: 0.310nMAssay Description:Binding affinity to human FRalpha expressed in Chinese hamster RT16 cells assessed as antiproliferative activity measured as reduction in cell growth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126172BDBM50126172(CHEMBL3628344)
Affinity DataIC50: 0.330nMAssay Description:Binding affinity to human FRalpha expressed in Chinese hamster RT16 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126172BDBM50126172(CHEMBL3628344)
Affinity DataIC50: 0.330nMAssay Description:Binding affinity to human FRalpha expressed in Chinese hamster RT16 cells assessed as antiproliferative activity measured as reduction in cell growth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50557568BDBM50557568(CHEMBL4790375)
Affinity DataIC50: 0.340nMAssay Description:Inhibition of human FRalpha expressed in Chinese Hamster MTXRII-OuaR2-4 R2 cells assessed as reduction in cell proliferation after 96 hrs by CellTite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50503238BDBM50503238(CHEMBL4465095)
Affinity DataIC50: 0.360nMAssay Description:Binding affinity to human FRalpha expressed in Chinese hamster RT16 cells assessed as antiproliferative activity measured as reduction in cell growth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50059342BDBM50059342((S)-2-({5-[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimi...)
Affinity DataKd:  0.380nMAssay Description:compound was tested for the ability to function as transport substrates for the human folate-binding protein(mFBP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50354833BDBM50354833(CHEMBL1834488 | AGF94)
Affinity DataIC50: 0.380nMAssay Description:Binding affinity to human FRalpha expressed in Chinese hamster RT16 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50557569BDBM50557569(CHEMBL4759798)
Affinity DataIC50: 0.440nMAssay Description:Inhibition of human FRalpha expressed in Chinese Hamster MTXRII-OuaR2-4 R2 cells assessed as reduction in cell proliferation after 96 hrs by CellTite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50534428BDBM50534428(CHEMBL4467936)
Affinity DataIC50: 0.510nMAssay Description:Inhibition of human FR-alpha receptor expressed in Chinese hamster RT16 cells assessed as antiproliferative activity measured as reduction in cell vi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50059338BDBM50059338((S)-2-{[6-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimidin...)
Affinity DataKd:  0.570nMAssay Description:compound was tested for the ability to function as transport substrates for the human folate-binding protein(mFBP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50503237BDBM50503237(CHEMBL4540298)
Affinity DataIC50: 0.580nMAssay Description:Binding affinity to human FRalpha expressed in Chinese hamster RT16 cells assessed as antiproliferative activity measured as reduction in cell growth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126174BDBM50126174(CHEMBL3628346)
Affinity DataIC50: 0.610nMAssay Description:Binding affinity to human FRalpha expressed in Chinese hamster RT16 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50503239BDBM50503239(CHEMBL4557278)
Affinity DataIC50: 0.690nMAssay Description:Binding affinity to human FRalpha expressed in Chinese hamster RT16 cells assessed as antiproliferative activity measured as reduction in cell growth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50059330BDBM50059330((S)-2-({5-[2-(2-Amino-4-oxo-4,6,7,8-tetrahydro-3H-...)
Affinity DataKd:  0.690nMAssay Description:compound was tested for the ability to function as transport substrates for the human folate-binding protein(mFBP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50557564BDBM50557564(CHEMBL4783397)
Affinity DataIC50: 0.910nMAssay Description:Inhibition of human FRalpha expressed in Chinese Hamster MTXRII-OuaR2-4 R2 cells assessed as reduction in cell proliferation after 96 hrs by CellTite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50059331BDBM50059331((R)-2-({5-[2-(2-Amino-4-oxo-4,6,7,8-tetrahydro-3H-...)
Affinity DataKd:  0.950nMAssay Description:compound was tested for the ability to function as transport substrates for the human folate-binding protein(mFBP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50534426BDBM50534426(CHEMBL4553188)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human FR-alpha receptor expressed in Chinese hamster RT16 cells assessed as antiproliferative activity measured as reduction in cell vi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50557570BDBM50557570(CHEMBL4761741)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human FRalpha expressed in Chinese Hamster MTXRII-OuaR2-4 R2 cells assessed as reduction in cell proliferation after 96 hrs by CellTite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50503236BDBM50503236(CHEMBL4538151)
Affinity DataIC50: 1.10nMAssay Description:Binding affinity to human FRalpha expressed in Chinese hamster RT16 cells assessed as antiproliferative activity measured as reduction in cell growth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50457435BDBM50457435(CHEMBL4214638)
Affinity DataIC50: 1.30nMAssay Description:Binding affinity to human FR-alpha receptor expressed in Chinese hamster RT16 cells assessed as antiproliferative activity measured as reduction in c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50457435BDBM50457435(CHEMBL4214638)
Affinity DataIC50: 1.30nMAssay Description:Binding affinity to human FRalpha expressed in Chinese hamster RT16 cells assessed as antiproliferative activity measured as reduction in cell growth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50529284BDBM50529284(CHEMBL4435608)
Affinity DataIC50: 1.40nMAssay Description:Binding affinity to human FRalpha expressed in Chinese hamster RT16 cells assessed as antiproliferative activity measured as reduction in cell growth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50503241BDBM50503241(CHEMBL4441626)
Affinity DataIC50: 1.40nMAssay Description:Binding affinity to human FRalpha expressed in Chinese hamster RT16 cells assessed as antiproliferative activity measured as reduction in cell growth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50571075BDBM50571075(CHEMBL4852455)
Affinity DataIC50: 1.40nMAssay Description:Displacement of [3H]-folic acid from FRalpha (unknown origin) expressed in human KB cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306576BDBM50306576((S)-2-({5-[4-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo...)
Affinity DataIC50: 1.80nMAssay Description:Binding affinity to human FRalpha expressed in Chinese hamster RT16 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50529285BDBM50529285(CHEMBL4562619)
Affinity DataIC50: 1.80nMAssay Description:Binding affinity to human FRalpha expressed in Chinese hamster RT16 cells assessed as antiproliferative activity measured as reduction in cell growth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50534431BDBM50534431(CHEMBL4447805)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human FR-alpha receptor expressed in Chinese hamster RT16 cells assessed as antiproliferative activity measured as reduction in cell vi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393640BDBM50393640(CHEMBL2158681)
Affinity DataIC50: 2.5nMAssay Description:Binding affinity to human FRalpha expressed in Chinese hamster RT16 cells assessed as antiproliferative activity measured as reduction in cell growth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50557566BDBM50557566(CHEMBL4741259)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human FRalpha expressed in Chinese Hamster MTXRII-OuaR2-4 R2 cells assessed as reduction in cell proliferation after 96 hrs by CellTite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50534430BDBM50534430(CHEMBL4471269)
Affinity DataIC50: 3nMAssay Description:Inhibition of human FR-alpha receptor expressed in Chinese hamster RT16 cells assessed as antiproliferative activity measured as reduction in cell vi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50534427BDBM50534427(CHEMBL4437824)
Affinity DataIC50: 3nMAssay Description:Inhibition of human FR-alpha receptor expressed in Chinese hamster RT16 cells assessed as antiproliferative activity measured as reduction in cell vi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50171513BDBM50171513((S)-2-(4-(3-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[...)
Affinity DataIC50: 4.10nMAssay Description:Binding affinity to human FRalpha expressed in Chinese hamster RT16 cells assessed as antiproliferative activity measured as reduction in cell growth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50457433BDBM50457433(CHEMBL4213181)
Affinity DataIC50: 4.40nMAssay Description:Binding affinity to human FR-alpha receptor expressed in Chinese hamster RT16 cells assessed as antiproliferative activity measured as reduction in c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50534429BDBM50534429(CHEMBL4444011)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of human FR-alpha receptor expressed in Chinese hamster RT16 cells assessed as antiproliferative activity measured as reduction in cell vi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50557565BDBM50557565(CHEMBL4755197)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of human FRalpha expressed in Chinese Hamster MTXRII-OuaR2-4 R2 cells assessed as reduction in cell proliferation after 96 hrs by CellTite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50171511BDBM50171511(N-{4-[4-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-...)
Affinity DataIC50: 6.30nMAssay Description:Binding affinity to human FR-alpha receptor expressed in Chinese hamster RT16 cells assessed as antiproliferative activity measured as reduction in c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50171511BDBM50171511(N-{4-[4-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-...)
Affinity DataIC50: 6.30nMAssay Description:Binding affinity to human FRalpha expressed in Chinese hamster RT16 cells assessed as antiproliferative activity measured as reduction in cell growth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50027659BDBM50027659(CHEMBL3335604)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of FRalpha (unknown origin) expressed in Chinese hamster RT16 cells assessed as cell growth inhibition incubated up to 96 hrs by Celltiter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50571074BDBM50571074(CHEMBL4866304)
Affinity DataIC50: 6.90nMAssay Description:Displacement of [3H]-folic acid from FRalpha (unknown origin) expressed in human KB cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50529282BDBM50529282(CHEMBL4515056)
Affinity DataIC50: 7.80nMAssay Description:Binding affinity to human FRalpha expressed in Chinese hamster RT16 cells assessed as antiproliferative activity measured as reduction in cell growth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249877BDBM50249877((S)-2-(4-(4-(2-amino-4-oxo-3,4-dihydrothieno[2,3-d...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human FRalpha expressed in Chinese Hamster MTXRII-OuaR2-4 R2 cells assessed as reduction in cell proliferation after 96 hrs by CellTite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50027654BDBM50027654(CHEMBL3335605)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of FRalpha (unknown origin) expressed in Chinese hamster RT16 cells assessed as cell growth inhibition incubated up to 96 hrs by Celltiter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652496BDBM50652496(CHEMBL5647334)
Affinity DataKd:  10nMAssay Description:Binding affinity to Folate receptor alpha in human KB cells assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetFolate receptor alpha(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50557567BDBM50557567(CHEMBL4789686)
Affinity DataIC50: 11nMAssay Description:Inhibition of human FRalpha expressed in Chinese Hamster MTXRII-OuaR2-4 R2 cells assessed as reduction in cell proliferation after 96 hrs by CellTite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
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