Compile Data Set for Download or QSAR
Report error Found 10 of affinity data for UniProtKB/TrEMBL: O88704
LigandPNGBDBM50535442(CHEMBL4453882)
Affinity DataEC50:  2.10E+4nMAssay Description:Inhibition of mouse HCN1 expressed in HEK293 cells assessed as reduction in hyperpolarization activated current at holding potential of -80 mV by pat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
LigandPNGBDBM50326988(3-(3-{[2-(3,4-Dimethoxy-phenyl)-ethyl]-methyl-amin...)
Affinity DataEC50:  1.68E+4nMAssay Description:Blockade of mouse HCN1 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50326985(3,3'-((2Z,2'Z)-4,4'-(3,4-dimethoxyphenethylazanedi...)
Affinity DataEC50:  1.07E+5nMAssay Description:Blockade of mouse HCN1 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50326989(3-((Z)-4-(((R)-2-(3,4-dimethoxyphenyl)propyl)(meth...)
Affinity DataEC50:  9.41E+3nMAssay Description:Blockade of mouse HCN1 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50326992(ivabradine | CHEMBL471737)
Affinity DataEC50:  4.50E+3nMAssay Description:Blockade of mouse HCN1 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50326990(3,3'-((2Z,2'Z)-4,4'-((R)-2-(3,4-dimethoxyphenyl)pr...)
Affinity DataEC50:  600nMAssay Description:Blockade of mouse HCN1 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50326987(3-((Z)-4-(((S)-2-(3,4-dimethoxyphenyl)propyl)(meth...)
Affinity DataEC50:  3.13E+4nMAssay Description:Blockade of mouse HCN1 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50326991(3-((E)-4-((3,4-dimethoxyphenethyl)(methyl)amino)bu...)
Affinity DataEC50:  2.31E+3nMAssay Description:Blockade of mouse HCN1 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50326993(3-((Z)-4-((3,4-dimethoxyphenethyl)(methyl)amino)bu...)
Affinity DataEC50:  5.60E+3nMAssay Description:Blockade of mouse HCN1 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50326986(3,3'-((2Z,2'Z)-4,4'-((S)-2-(3,4-dimethoxyphenyl)pr...)
Affinity DataEC50:  1.79E+4nMAssay Description:Blockade of mouse HCN1 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed