Compile Data Set for Download or QSAR
maximum 50k data
Found 2306 for UniProtKB: P08909
TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM50218398(CHEMBL1907861)
Affinity DataKi:  0.0900nMAssay Description:Binding affinity at 5-hydroxytryptamine 2 receptor from striata wistar rats by [3H]ketanserin displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM50069019(7-Chloro-1-(4-fluoro-phenyl)-8,9-dimethoxy-4-methy...)
Affinity DataKi:  0.0900nMAssay Description:Affinity for 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM50004819(8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-1-phenyl-3-pro...)
Affinity DataKi:  0.0960nMAssay Description:The compound was tested in vitro for binding affinity towards 5-hydroxytryptamine 2 receptor by displacing [125]I-LSD radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50098525(2-(8-Bromo-benzo[1,2-b;4,5-b']difuran-4-yl)-1-meth...)
Affinity DataKi:  0.110nMAssay Description:Binding affinity at cloned rat 5-hydroxytryptamine 2C receptor using [3H]-DOI as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM50004807(8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-isobutyl-1-p...)
Affinity DataKi:  0.130nMAssay Description:The compound was tested in vitro for binding affinity towards 5-hydroxytryptamine 2 receptor by displacing [125]I-LSD radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM50218392(CHEMBL79277)
Affinity DataKi:  0.140nMAssay Description:Binding affinity at 5-hydroxytryptamine 2 receptor from striata wistar rats by [3H]ketanserin displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50145624(CHEMBL3764539)
Affinity DataKi:  0.156nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptor in Sprague-Dawley rat brain cortex incubated for 15 mins by liquid scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50115642((+)-65-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro-2,...)
Affinity DataKi:  0.160nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 2C receptor was determined using [3H]-mesulergineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM85097(CAS_181632-25-7 | CHEMBL14563 | SB 242084)
Affinity DataKi:  0.160nMAssay Description:Displacement of [3H]mesulergine from 5HT2C in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM50025124(3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-...)
Affinity DataKi:  0.170nMAssay Description:Evaluated for binding activity against [3H]ketanserin as radioligand for 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50001775((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...)
Affinity DataKi:  0.200nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM50001885((risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-...)
Affinity DataKi:  0.200nMAssay Description:Affinity for 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM50001885((risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-...)
Affinity DataKi:  0.200nMAssay Description:The binding affinity was measured on 5-hydroxytryptamine 2 receptor in rat brain tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50115643((+/-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro...)
Affinity DataKi:  0.210nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 2C receptor was determined using [3H]-mesulergineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM50218396(CHEMBL315259)
Affinity DataKi:  0.240nMAssay Description:Binding affinity at 5-hydroxytryptamine 2 receptor from striata wistar rats by [3H]ketanserin displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50098526(2-(8-Bromo-benzo[1,2-b;4,5-b']difuran-4-yl)-1-meth...)
Affinity DataKi:  0.25nMAssay Description:Binding affinity at cloned rat 5-hydroxytryptamine 2C receptor using [3H]-DOI as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50098532(2-(8-Bromo-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-b']d...)
Affinity DataKi:  0.260nMAssay Description:Binding affinity at cloned rat 5-hydroxytryptamine 2C receptor using [3H]-DOI as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM50010044(2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-...)
Affinity DataKi:  0.260nMAssay Description:Binding affinity to rat cerebral cortex homogenate 5-HT2 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM50010044(2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-...)
Affinity DataKi:  0.260nMAssay Description:Binding constant against 5-hydroxytryptamine 2 receptor (in vivo)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM50001775((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...)
Affinity DataKi:  0.260nMAssay Description:The compound was tested for its binding affinity towards 5-hydroxytryptamine 2 receptor by displacing [3H]ketanserin radioligand in rat cerebral cort...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM50024205(3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-...)
Affinity DataKi:  0.300nMAssay Description:Evaluated for the binding affinity to rat cortical membranes at 5-hydroxytryptamine 2 receptor binding site by using [3H]- KET as a radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM30704((phenylmethyl) N-[[(6aR,9S,10aR)-4,7-dimethyl-6,6a...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity to rat cortical membranes at 5-hydroxytryptamine 2 (5-HT2) receptor using [3H]KET as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM50004818(3-Ethyl-8-[4-(4-fluoro-phenyl)-4-oxo-butyl]-1-phen...)
Affinity DataKi:  0.310nMAssay Description:The compound was tested in vitro for binding affinity towards 5-hydroxytryptamine 2 receptor by displacing [125]I-LSD radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM50218397(CHEMBL83611)
Affinity DataKi:  0.320nMAssay Description:Binding affinity at 5-hydroxytryptamine 2 receptor from striata wistar rats by [3H]ketanserin displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50115640((-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro-2...)
Affinity DataKi:  0.390nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 2C receptor was determined using [3H]-mesulergineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM50064708((R)-1-(4-bromo-2,5-dimethoxyphenyl)propan-2-amine ...)
Affinity DataKi:  0.390nMAssay Description:Affinity towards [3H]- DOB -labeled 5-hydroxytryptamine 2 receptor sites in rat cortical homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50098530(1-Methyl-2-(8-trifluoromethyl-benzo[1,2-b;4,5-b']d...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity at cloned rat 5-hydroxytryptamine 2C receptor using [3H]-DOI as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM35256((S)-mianserin | Lerivon | MIANSERIN | MIANSERIN (+...)
Affinity DataKi:  0.400nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM50064708((R)-1-(4-bromo-2,5-dimethoxyphenyl)propan-2-amine ...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity to rat cortical membranes at 5-hydroxytryptamine 2 receptor binding site by using [3H]- DOB as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM21395(3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H...)
Affinity DataKi:  0.400nMAssay Description:Evaluated for the binding affinity to hippocampus striatal membranes at 5-hydroxytryptamine 1A receptor binding site by using [3H]-8-OH- DPAT as a ra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM50069011(1-(4-Fluoro-phenyl)-8,9-dimethoxy-4-methyl-2,2a,3,...)
Affinity DataKi:  0.410nMAssay Description:Affinity for 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM50004805(3-Butyl-8-[4-(4-fluoro-phenyl)-4-oxo-butyl]-1-phen...)
Affinity DataKi:  0.410nMAssay Description:The compound was tested in vitro for binding affinity towards 5-hydroxytryptamine 2 receptor by displacing [125]I-LSD radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM50218399(CHEMBL79643)
Affinity DataKi:  0.440nMAssay Description:Binding affinity at 5-hydroxytryptamine 2 receptor from striata wistar rats by [3H]ketanserin displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)
Affinity DataKi:  0.450nMAssay Description:The compound was tested in vitro for binding affinity towards 5-hydroxytryptamine 2 receptor by displacing [125]I-LSD radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity to rat cortical membranes at 5-hydroxytryptamine 2 (5-HT2) receptor using [3H]KET as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50001786(1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl...)
Affinity DataKi:  0.510nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50001786(1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl...)
Affinity DataKi:  0.510nMAssay Description:Displacement of [3H]mesulergine (0.5 nM) from rat 5-hydroxytryptamine 2C receptor expressed in SR-3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM50218391(CHEMBL79528)
Affinity DataKi:  0.550nMAssay Description:Binding affinity at 5-hydroxytryptamine 2 receptor from striata wistar rats by [3H]ketanserin displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50048803(5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)et...)
Affinity DataKi:  0.550nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM50004813(8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-methyl-1-phe...)
Affinity DataKi:  0.550nMAssay Description:The compound was tested in vitro for binding affinity towards 5-hydroxytryptamine 2 receptor by displacing [125]I-LSD radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50013050(CHEMBL3261693)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]mesulergine from 5-HT2C receptor in Sprague-Dawley rat choroid plexus membranes after 30 mins by liquid scintillation spectrophot...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50140071(CHEMBL3752465)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]mesulergine from 5HT2C in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM50040237(2-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f]...)
Affinity DataKi:  0.600nMAssay Description:In vitro binding affinity against rat 5-hydroxytryptamine 2 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM50001775((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...)
Affinity DataKi:  0.610nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 2 receptor in rat striatal membranes by [3H]ketanserin displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM50069016(1-(4-Fluoro-phenyl)-4-methyl-2,2a,3,4,5,6-hexahydr...)
Affinity DataKi:  0.620nMAssay Description:Affinity for 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50214315(CHEMBL90709)
Affinity DataKi:  0.631nMAssay Description:Compound was evaluated for displacement of [3H]mesulergine from cloned rat 5-hydroxytryptamine 2C receptor in transfected CHO-K1 cells.More data for this Ligand-Target Pair
In DepthDetails
TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM21395(3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H...)
Affinity DataKi:  0.660nMAssay Description:Binding affinity at 5-hydroxytryptamine 2 receptor from striata wistar rats by [3H]ketanserin displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM21395(3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H...)
Affinity DataKi:  0.660nMAssay Description:Binding affinity for 5-hydroxytryptamine 2 receptor from striata of male Wistar rats by displacement of [3H]ketanserinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM50004814(8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-(2-nitro-ben...)
Affinity DataKi:  0.680nMAssay Description:The compound was tested in vitro for binding affinity towards 5-hydroxytryptamine 2 receptor by displacing [125]I-LSD radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50098536(1-Methyl-2-(8-trifluoromethyl-benzo[1,2-b;4,5-b']d...)
Affinity DataKi:  0.690nMAssay Description:Binding affinity at cloned rat 5-hydroxytryptamine 2C receptor using [3H]-DOI as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 2306 total ) | Next | Last >>
Jump to: