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TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247512(CHEMBL436524 | CHEBI:52279)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate after 15 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2019
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247524(CHEMBL4078465)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate after 15 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2019
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247525(CHEMBL4070279)
Affinity DataEC50:  8.28E+4nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate after 15 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2019
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247526(CHEMBL4080916)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate after 15 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2019
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247527(CHEMBL4105160)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate after 15 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2019
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247528(CHEMBL4099866)
Affinity DataEC50:  1.47E+3nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate after 15 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2019
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247529(CHEMBL4084530)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate after 15 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2019
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247512(CHEMBL436524 | CHEBI:52279)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2019
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247530(CHEMBL374342)
Affinity DataEC50:  563nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2019
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247525(CHEMBL4070279)
Affinity DataEC50:  6.34E+4nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2019
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247531(CHEMBL4097456)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2019
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247527(CHEMBL4105160)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2019
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247528(CHEMBL4099866)
Affinity DataEC50:  381nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2019
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247532(CHEMBL4081867)
Affinity DataEC50:  1.23E+3nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2019
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247529(CHEMBL4084530)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2019
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247528(CHEMBL4099866)
Affinity DataKd:  381nMAssay Description:Binding affinity to recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells by spectrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2019
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247530(CHEMBL374342)
Affinity DataEC50:  2.02E+3nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate after 15 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2019
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247531(CHEMBL4097456)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate after 15 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2019
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247532(CHEMBL4081867)
Affinity DataEC50:  1.97E+3nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate after 15 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2019
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247524(CHEMBL4078465)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2019
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247526(CHEMBL4080916)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2019
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50076922(1,11-dihydroxy-6-(2-hydroxy-1-hydroxymethylethylam...)
Affinity DataEC50:  580nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50076920(1,11-dihydroxy-6-(2-hydroxyethylamino)-12-(3,4,5-t...)
Affinity DataEC50:  430nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50076932(2-[1,11-dihydroxy-5,7-dioxo-12-(3,4,5-trihydroxy-6...)
Affinity DataEC50:  9.50E+3nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50076933(1,11-dihydroxy-6-(3-hydroxybenzylamino)-12-(3,4,5-...)
Affinity DataEC50:  300nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50076935(6-(2,3-dihydroxypropylamino)-1,11-dihydroxy-12-(3,...)
Affinity DataEC50:  1.00E+3nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50076924(N-[1,11-dihydroxy-5,7-dioxo-12-(3,4,5-trihydroxy-6...)
Affinity DataEC50:  580nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50076930(1N-[1,11-dihydroxy-5,7-dioxo-12-(3,4,5-trihydroxy-...)
Affinity DataEC50:  1.00E+3nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50076941(1,11-dihydroxy-6-(4-methylphenylsulfonamido)-5,7-d...)
Affinity DataEC50:  270nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50076943(N-[1,11-dihydroxy-5,7-dioxo-12-(3,4,5-trihydroxy-6...)
Affinity DataEC50:  700nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50076923(6-amino-1,11-dihydroxy-12-(3,4,5-trihydroxy-6-hydr...)
Affinity DataEC50:  270nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50076936(1,11-dihydroxy-6-propylamino-12-(3,4,5-trihydroxy-...)
Affinity DataEC50:  1.20E+3nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50076940(1,11-dihydroxy-6-methylamino-12-(3,4,5-trihydroxy-...)
Affinity DataEC50:  350nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50076926(1,11-dihydroxy-5,7-dioxo-6-phenylcarboxamido-12-(3...)
Affinity DataEC50:  52nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50073855(1,11-dihydroxy-12-(3,4,5-trihydroxy-6-hydroxymethy...)
Affinity DataEC50:  3.00E+3nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50076934(1N-[1,11-dihydroxy-5,7-dioxo-12-(3,4,5-trihydroxy-...)
Affinity DataEC50:  170nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50076925(1,11-dihydroxy-5,7-dioxo-6-(2-pyridylcarboxamido)-...)
Affinity DataEC50:  90nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50076928(1,11-dihydroxy-6,7,12,13-tetrahydro-5H-indolo[2,3-...)
Affinity DataEC50: >3.00E+3nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50076929(1,11-dihydroxy-5,7-dioxo-6-(2-pyridylcarboxamido)-...)
Affinity DataEC50:  550nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50076939(6-dimethylamino-1,11-dihydroxy-12-(3,4,5-trihydrox...)
Affinity DataEC50: >1.00E+4nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50076944(4-[1,11-dihydroxy-5,7-dioxo-12-(3,4,5-trihydroxy-6...)
Affinity DataEC50:  160nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50076942(6-ethylamino-1,11-dihydroxy-12-(3,4,5-trihydroxy-6...)
Affinity DataEC50:  3.50E+3nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50076937(6-phenylamino-1,11-dihydroxy-12-(3,4,5-trihydroxy-...)
Affinity DataEC50:  250nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50076927(1N-[1,11-dihydroxy-5,7-dioxo-12-(3,4,5-trihydroxy-...)
Affinity DataEC50:  2.80E+3nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50076938(2-[1,11-dihydroxy-5,7-dioxo-12-(3,4,5-trihydroxy-6...)
Affinity DataEC50:  70nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50076931(1N-[1,11-dihydroxy-5,7-dioxo-12-(3,4,5-trihydroxy-...)
Affinity DataEC50:  480nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50076921(6-amino-1,11-dihydroxy-12-(3,4,5-trihydroxy-6-hydr...)
Affinity DataEC50:  360nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50083598(2-hydroxy-6-(2-hydroxy-1-hydroxymethylethylamino)-...)
Affinity DataEC50:  650nMAssay Description:In vitro inhibition of Topoisomerase I-mediated DNA cleavage using supercoiled pBR322 plasmid DNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50083600(2,10-dihydroxy-6-(2-hydroxy-1-hydroxymethylethylam...)
Affinity DataEC50:  51nMAssay Description:In vitro inhibition of Topoisomerase I-mediated DNA cleavage using supercoiled pBR322 plasmid DNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50083603(3,9-dihydroxy-6-(2-hydroxy-1-hydroxymethylethylami...)
Affinity DataEC50:  210nMAssay Description:In vitro inhibition of Topoisomerase I-mediated DNA cleavage using supercoiled pBR322 plasmid DNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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