Compile Data Set for Download or QSAR
Report error Found 55 of affinity data for UniProtKB/TrEMBL: P15170
LigandChemical structure of BindingDB Monomer ID 50631119BDBM50631119(CHEMBL4170596)
Affinity DataEC50:  0.300nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 20 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50631145BDBM50631145(CHEMBL5407904)
Affinity DataEC50:  21nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 20 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50631149BDBM50631149(CHEMBL5419778)
Affinity DataEC50:  70nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 20 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50631146BDBM50631146(CHEMBL5427975)
Affinity DataEC50:  100nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 20 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50649680BDBM50649680(CHEMBL5618808)
Affinity DataEC50:  170nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 60 mins by luminescence reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50649681BDBM50649681(CHEMBL5620230)
Affinity DataEC50:  550nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 60 mins by luminescence reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50649686BDBM50649686(CHEMBL5619824)
Affinity DataEC50:  1.10E+3nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 60 mins by luminescence reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50649687BDBM50649687(CHEMBL5618377)
Affinity DataEC50:  1.40E+3nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 60 mins by luminescence reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50649675BDBM50649675(CHEMBL5618477)
Affinity DataEC50: >3.10E+3nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 60 mins by luminescence reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50649685BDBM50649685(CHEMBL5618646)
Affinity DataEC50:  3.30E+3nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 60 mins by luminescence reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50649682BDBM50649682(CHEMBL5618970)
Affinity DataEC50:  4.30E+3nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 60 mins by luminescence reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50649683BDBM50649683(CHEMBL5619492)
Affinity DataEC50:  5.10E+3nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 60 mins by luminescence reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50649684BDBM50649684(CHEMBL5618672)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 60 mins by luminescence reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50649689BDBM50649689(CHEMBL5619918)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 60 mins by luminescence reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50649688BDBM50649688(CHEMBL5618952)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 60 mins by luminescence reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50649691BDBM50649691(CHEMBL5619063)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 60 mins by luminescence reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50649690BDBM50649690(CHEMBL5618357)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 60 mins by luminescence reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50631143BDBM50631143(CHEMBL5430384)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 20 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50649669BDBM50649669(CHEMBL5619691)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 60 mins by luminescence reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50631144BDBM50631144(CHEMBL5428693)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 20 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50649668BDBM50649668(CHEMBL5618142)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 60 mins by luminescence reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50365463BDBM50365463(CHEMBL1232461)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GSPT1 (unknown origin) incubated for 1 hr by colloidal coomassie staining based LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50631141BDBM50631141(CHEMBL5398719)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 20 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50631142BDBM50631142(CHEMBL5394519)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 20 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50631147BDBM50631147(CHEMBL5427589)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 20 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50649673BDBM50649673(CHEMBL5619144)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 60 mins by luminescence reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50631148BDBM50631148(CHEMBL5410293)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 20 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50649672BDBM50649672(CHEMBL5619864)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 60 mins by luminescence reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50649671BDBM50649671(CHEMBL5619187)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 60 mins by luminescence reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50649670BDBM50649670(CHEMBL5619101)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 60 mins by luminescence reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50649677BDBM50649677(CHEMBL5619015)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 60 mins by luminescence reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50649676BDBM50649676(CHEMBL5619449)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 60 mins by luminescence reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50631150BDBM50631150(CHEMBL5408444)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 20 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50649674BDBM50649674(CHEMBL5620287)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 60 mins by luminescence reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50649679BDBM50649679(CHEMBL5618239)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 60 mins by luminescence reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50649678BDBM50649678(CHEMBL5619325)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 60 mins by luminescence reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50631139BDBM50631139(CHEMBL5437182)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 20 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50631140BDBM50631140(CHEMBL5403728)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 20 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 65497BDBM65497(CC-220 (Compound 6) | US9694015, 6.4S)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 20 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 525983BDBM525983(3-(5-(methyl((1R,2R)-2- (methylamino)cyclohexyl)am...)
Affinity DataEC50: >3.00E+4nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526006BDBM526006(3-(5-(((1S,2S)-2- (benzylamino)cyclohexyl)amino)-1...)
Affinity DataEC50: >3.00E+4nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526020BDBM526020(3-(5-(((1S,2S)-2-(benzyloxy) cyclohexyl)amino)- 1-...)
Affinity DataEC50: >3.00E+4nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 525977BDBM525977(3-(5-(((1S,2S)-2- hydroxycyclohexyl)amino)-1- oxoi...)
Affinity DataEC50: >3.00E+4nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526078BDBM526078(US11185537, Compound I-9 | US11185537, Compound I-...)
Affinity DataEC50: >5.00E+4nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526282BDBM526282(5-(((1S,2S)-2- (dimethylamino)cyclohexyl)amino)-2-...)
Affinity DataEC50: >5.00E+4nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526271BDBM526271(2-(2,6-dioxopiperidin-3- yl)-5-(methyl((1S,2S)-2- ...)
Affinity DataEC50: >5.00E+4nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526272BDBM526272(5-(((1S,2S)-2-aminocyclohexyl) (methyl)amino)- 2-(...)
Affinity DataEC50: >5.00E+4nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526265BDBM526265(3-(5-(((1S,2S)-2- (isopropylamino)cyclohexyl)amino...)
Affinity DataEC50: >5.00E+4nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526273BDBM526273(2-(2,6-dioxopiperidin-3-yl)-5-(((1S,2S)-2- (ethyla...)
Affinity DataEC50: >5.00E+4nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526078BDBM526078(US11185537, Compound I-9 | US11185537, Compound I-...)
Affinity DataEC50: >5.00E+4nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

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