Compile Data Set for Download or QSAR
Report error Found 162 of affinity data for UniProtKB/TrEMBL: P23204
LigandChemical structure of BindingDB Monomer ID 50171900BDBM50171900((S)-3-Phenyl-2-(4-thiophen-2-yl-phenoxy)-propionic...)
Affinity DataEC50:  0.150nMAssay Description:Effective concentration against murine PPARalpha in transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28759BDBM28759(CHEMBL191275 | (2S)-3-phenyl-2-(4-phenylphenoxy)pr...)
Affinity DataEC50:  0.200nMAssay Description:Effective concentration against murine PPARalpha in transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50171898BDBM50171898((S)-3-Phenyl-2-(4-trifluoromethyl-phenoxy)-propion...)
Affinity DataEC50:  0.270nMAssay Description:Effective concentration against murine PPARalpha in transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50171895BDBM50171895((2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid | (...)
Affinity DataEC50:  0.350nMAssay Description:Effective concentration against murine PPARalpha in transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50099491BDBM50099491(cid_3392731 | CHEMBL21241 | 2-(4-{2-[3-Cyclohexyl-...)
Affinity DataEC50:  1nMAssay Description:Activation of murine PPAR alpha ligand binding domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50171897BDBM50171897((S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid | (...)
Affinity DataEC50:  1.30nMAssay Description:Effective concentration against murine PPARalpha in transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50568096BDBM50568096(CHEMBL4866115)
Affinity DataEC50:  3nMAssay Description:Agonist activity at Gal4-fused mouse PPARalpha co-expressed with RXRalpha in monkey CV1 cells assessed as PPRE transcriptional activation incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50568100BDBM50568100(CHEMBL4861761)
Affinity DataEC50:  3nMAssay Description:Agonist activity at Gal4-fused mouse PPARalpha co-expressed with RXRalpha in monkey CV1 cells assessed as PPRE transcriptional activation incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28799BDBM28799(2-{[4-(2-{[(2,4-difluorophenyl)carbamoyl](heptyl)a...)
Affinity DataEC50:  5nMAssay Description:Agonist activity for murine PPAR alpha receptor in transcriptional activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28799BDBM28799(2-{[4-(2-{[(2,4-difluorophenyl)carbamoyl](heptyl)a...)
Affinity DataEC50:  5nMAssay Description:Compound was tested for its agonist activity against murine Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor transfected CV-1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50568097BDBM50568097(CHEMBL4879102)
Affinity DataEC50:  10nMAssay Description:Agonist activity at Gal4-fused mouse PPARalpha co-expressed with RXRalpha in monkey CV1 cells assessed as PPRE transcriptional activation incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28799BDBM28799(2-{[4-(2-{[(2,4-difluorophenyl)carbamoyl](heptyl)a...)
Affinity DataEC50:  10nMAssay Description:Agonist activity at Gal4-fused mouse PPARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50568102BDBM50568102(CHEMBL4847453)
Affinity DataEC50:  10nMAssay Description:Agonist activity at Gal4-fused mouse PPARalpha co-expressed with RXRalpha in monkey CV1 cells assessed as PPRE transcriptional activation incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50081223BDBM50081223(2-(4-{2-[3-(2,4-Difluoro-phenyl)-1-heptyl-ureido]-...)
Affinity DataEC50:  10nMAssay Description:Compound was tested for its agonist activity against murine Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor transfected CV-1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50584465BDBM50584465(CHEMBL5084377)
Affinity DataEC50:  17nMAssay Description:Agonist activity at mouse PPARalpha transfected in Cos7 cells co-expressing with pBIND and pGL4.35 Gal4 UAS Luc reporter plasmid by measuring lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50568098BDBM50568098(CHEMBL4877444)
Affinity DataEC50:  20nMAssay Description:Agonist activity at Gal4-fused mouse PPARalpha co-expressed with RXRalpha in monkey CV1 cells assessed as PPRE transcriptional activation incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319262BDBM50319262(2-(4-(((2-(2,4-dimethylphenylamino)-2-oxoethyl)(fu...)
Affinity DataEC50:  20nMAssay Description:Agonist activity at Gal4-fused mouse PPARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50568103BDBM50568103(CHEMBL4847989)
Affinity DataEC50:  20nMAssay Description:Agonist activity at Gal4-fused mouse PPARalpha co-expressed with RXRalpha in monkey CV1 cells assessed as PPRE transcriptional activation incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50568099BDBM50568099(CHEMBL4855604)
Affinity DataEC50:  20nMAssay Description:Agonist activity at Gal4-fused mouse PPARalpha co-expressed with RXRalpha in monkey CV1 cells assessed as PPRE transcriptional activation incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50244809BDBM50244809((2R)-2-[3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(triflu...)
Affinity DataEC50:  28nMAssay Description:Agonist activity at mouse PPARalpha receptor expressed in african green monkey COS1 cells co-transfected with fused yeast Gal4-DBD by transactivation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50568101BDBM50568101(CHEMBL4870407)
Affinity DataEC50:  30nMAssay Description:Agonist activity at Gal4-fused mouse PPARalpha co-expressed with RXRalpha in monkey CV1 cells assessed as PPRE transcriptional activation incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50373907BDBM50373907(CHEMBL271394)
Affinity DataEC50:  30nMAssay Description:Agonist activity at mouse PPARalpha expressed in CV1 cells by transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50225835BDBM50225835((2s,5s)-2-methyl-5-(4-(5-methyl-2-p-tolyloxazol-4-...)
Affinity DataEC50:  30nMAssay Description:Agonist activity at mouse PPARalpha expressed in CV1 cells by transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50081225BDBM50081225(2-(4-{2-[3-(4-Fluoro-phenyl)-1-heptyl-ureido]-ethy...)
Affinity DataEC50:  33nMAssay Description:Compound was tested for its agonist activity against murine Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor transfected CV-1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 24566BDBM24566(JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...)
Affinity DataEC50:  40nMAssay Description:Effective concentration against murine PPARalpha in transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50293847BDBM50293847((2R)-2-{3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(triflu...)
Affinity DataEC50:  40nMAssay Description:Agonist activity at mouse PPARalpha receptor expressed in african green monkey COS1 cells co-transfected with fused yeast Gal4-DBD by transactivation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28699BDBM28699(2-(4-chlorophenoxy)-2-methylpropanoic acid | CHEMB...)
Affinity DataEC50:  42nMAssay Description:Effective concentration against murine PPARalpha in transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50081224BDBM50081224(2-(4-{2-[1-(5-Cyclohexyl-pentyl)-3-(4-fluoro-pheny...)
Affinity DataEC50:  53nMAssay Description:Compound was tested for its agonist activity against murine Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor transfected CV-1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50030474BDBM50030474(US9562012, rosiglitazone | CHEBI:50122 | Avandamet...)
Affinity DataIC50: 80nMAssay Description:Activation of mouse liver PPARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50156523BDBM50156523(3-{4-[2-(2-Biphenyl-3-yl-5-methyl-oxazol-4-yl)-eth...)
Affinity DataEC50:  91nMAssay Description:Transactivation activity for mouse Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50373910BDBM50373910(CHEMBL410704)
Affinity DataEC50:  100nMAssay Description:Agonist activity at mouse PPARalpha expressed in CV1 cells by transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 24566BDBM24566(JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...)
Affinity DataKi:  100nMAssay Description:Binding affinity towards peroxisome proliferator activated receptor alpha (murinePPAR alpha)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50373024BDBM50373024(CHEMBL447533)
Affinity DataEC50:  100nMAssay Description:Agonist activity at mouse PPARalpha by transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50293849BDBM50293849((2R)-2-{3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(triflu...)
Affinity DataEC50:  110nMAssay Description:Agonist activity at mouse PPARalpha receptor expressed in african green monkey COS1 cells co-transfected with fused yeast Gal4-DBD by transactivation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50293851BDBM50293851((2R)-2-{3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(triflu...)
Affinity DataEC50:  120nMAssay Description:Agonist activity at mouse PPARalpha receptor expressed in african green monkey COS1 cells co-transfected with fused yeast Gal4-DBD by transactivation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50081222BDBM50081222(2-(4-{2-[1-Cycloheptyl-3-(2,4-difluoro-phenyl)-ure...)
Affinity DataEC50:  120nMAssay Description:Compound was tested for its agonist activity against murine Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor transfected CV-1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28802BDBM28802(2-{[(5-{[2-(4-chlorophenyl)-5-methyl-1,3-oxazol-4-...)
Affinity DataEC50:  144nMAssay Description:Agonist activity at mouse PPAR-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2017
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50156523BDBM50156523(3-{4-[2-(2-Biphenyl-3-yl-5-methyl-oxazol-4-yl)-eth...)
Affinity DataIC50: 146nMAssay Description:In vitro inhibition of mouse Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50293844BDBM50293844(1-{3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(trifluorome...)
Affinity DataEC50:  150nMAssay Description:Agonist activity at mouse PPARalpha receptor expressed in african green monkey COS1 cells co-transfected with fused yeast Gal4-DBD by transactivation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50156524BDBM50156524(3-{4-[2-(2-Biphenyl-3-yl-5-methyl-oxazol-4-yl)-eth...)
Affinity DataEC50:  151nMAssay Description:Transactivation activity for mouse Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50448033BDBM50448033(CHEMBL3115237)
Affinity DataEC50:  170nMAssay Description:Agonist activity at mouse PPARalpha expressed in CV-1 cells by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50145723BDBM50145723(3-{4-[2-(2-Biphenyl-3-yl-5-methyl-oxazol-4-yl)-eth...)
Affinity DataEC50:  173nMAssay Description:Transactivation activity for mouse Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50164210BDBM50164210(2-(5,7-Dipropyl-3-trifluoromethyl-benzo[d]isoxazol...)
Affinity DataEC50:  180nMAssay Description:Agonist activity against mouse Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50156527BDBM50156527(2-(4-tert-Butyl-phenoxy)-2-methyl-3-{4-[2-(5-methy...)
Affinity DataEC50:  211nMAssay Description:Transactivation activity for mouse Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50267991BDBM50267991((R)-2-(3-(3-(4-methoxybenzoyl)-2-methyl-6-(trifluo...)
Affinity DataEC50:  240nMAssay Description:Agonist activity at mouse PPARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28662BDBM28662(CHEMBL435278 | 2-[4-(3-{[2-(2-chloro-6-fluoropheny...)
Affinity DataEC50:  270nMAssay Description:Agonist activity for murine PPAR alpha receptor in transcriptional activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50293853BDBM50293853(2-[3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(trifluorome...)
Affinity DataEC50:  350nMAssay Description:Agonist activity at mouse PPARalpha receptor expressed in african green monkey COS1 cells co-transfected with fused yeast Gal4-DBD by transactivation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50293848BDBM50293848((2S)-2-{3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(triflu...)
Affinity DataEC50:  360nMAssay Description:Agonist activity at mouse PPARalpha receptor expressed in african green monkey COS1 cells co-transfected with fused yeast Gal4-DBD by transactivation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50244350BDBM50244350(CHEMBL4091374)
Affinity DataEC50:  366nMAssay Description:Transactivation of mouse GAL4-fused PPARalpha LBD expressed in African green monkey COS7 cells co-expressing 5Gal4 pGL3 TK Luc after overnight incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50145723BDBM50145723(3-{4-[2-(2-Biphenyl-3-yl-5-methyl-oxazol-4-yl)-eth...)
Affinity DataIC50: 404nMAssay Description:In vitro inhibition of mouse Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
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