Compile Data Set for Download or QSAR
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Found 320 of affinity data for UniProtKB/TrEMBL: P39086
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM85740(Dysiherbaine)
Affinity DataKi:  0.740nMAssay Description:Displacement of [3H]kianic acid from recombinant GluK1 kainate receptor (unknown origin) expressed in HEK293 cell membranes measured after 1 hrMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50031704((2S,4R)-2-Amino-4-methyl-pentanedioic acid | (2S,4...)
Affinity DataKi:  3nMAssay Description:Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50116042(CHEMBL63861 | {7-[3-(4-Benzyl-piperazin-1-ylmethyl...)
Affinity DataKi:  3.80nMAssay Description:Binding affinity towards cloned human GluR5 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50088223(CHEMBL61751 | E-2-Amino-4-(3-naphthalen-1-yl-allyl...)
Affinity DataKi:  7nMAssay Description:Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50088197(CHEMBL58590 | E-2-Amino-4-[3-(4-chloro-phenyl)-all...)
Affinity DataKi:  8nMAssay Description:Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50088197(CHEMBL58590 | E-2-Amino-4-[3-(4-chloro-phenyl)-all...)
Affinity DataKi:  8nMAssay Description:Compound was tested for binding affinity against Ionotropic glutamate receptor ionotropic kainate 1 in HK293 cells using [3H]-kainate as radioligand;...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM85741(ATPA | CAS_140158-50-5 | NSC_2253)
Affinity DataKi:  9.40nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50088229(2-Amino-4-prop-2-ynyl-pentanedioic acid | CHEMBL59...)
Affinity DataKi:  11.6nMAssay Description:Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50116048(CHEMBL67828 | {6-Nitro-2,3-dioxo-7-[3-(4-phenethyl...)
Affinity DataKi:  12nMAssay Description:Binding affinity towards cloned human GluR5 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50088222((2S,4R)-2-Amino-4-((E)-3-naphthalen-2-yl-allyl)-pe...)
Affinity DataKi:  14nMAssay Description:Compound was tested for binding affinity against Ionotropic glutamate receptor ionotropic kainate 1 in HK293 cells using [3H]-kainate as radioligand;...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50088222((2S,4R)-2-Amino-4-((E)-3-naphthalen-2-yl-allyl)-pe...)
Affinity DataKi:  15nMAssay Description:Compound was tested for binding affinity against Ionotropic glutamate receptor ionotropic kainate 1 in HK293 cells using [3H]-kainate as radioligand;...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50088222((2S,4R)-2-Amino-4-((E)-3-naphthalen-2-yl-allyl)-pe...)
Affinity DataKi:  15nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 1 using cell membranes prepared from HEK293 cell...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50494356(CHEMBL3088070)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]ATPA from human Gluk1 receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50088212(2-Amino-4-but-2-enyl-pentanedioic acid(LY339180) |...)
Affinity DataKi:  21nMAssay Description:Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM141501(US8921370, 2 | US9656975, 2)
Affinity DataKi:  27nMAssay Description:Binding assays were performed as described in [J. A. O'Brien et al. Mol Pharmacol., 2003, 64, 731-740] with slight modifications, including that ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50088228(2-Amino-4-but-2-ynyl-pentanedioic acid | CHEMBL620...)
Affinity DataKi:  28.9nMAssay Description:Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50088203(CHEMBL301915 | E-2-Amino-4-[3-(4-bromo-phenyl)-all...)
Affinity DataKi:  30nMAssay Description:Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50088216(CHEMBL59284 | E-2-Amino-4-[3-(2-methoxy-phenyl)-al...)
Affinity DataKi:  30nMAssay Description:Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50088216(CHEMBL59284 | E-2-Amino-4-[3-(2-methoxy-phenyl)-al...)
Affinity DataKi:  30nMAssay Description:Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50088235(CHEMBL300368 | E-2-Amino-4-[3-(4-methylsulfanyl-ph...)
Affinity DataKi:  32nMAssay Description:Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50091477((S)-2-Amino-4-cyclopentylidene-pentanedioic acid |...)
Affinity DataKi:  33nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 1 using cell membranes prepared from HEK293 cell...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM141506(US8921370, 160 | US9656975, 160)
Affinity DataKi:  35nMAssay Description:Binding assays were performed as described in [J. A. O'Brien et al. Mol Pharmacol., 2003, 64, 731-740] with slight modifications, including that ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM141505(US8921370, 126 | US9656975, 126)
Affinity DataKi:  39nMAssay Description:Binding assays were performed as described in [J. A. O'Brien et al. Mol Pharmacol., 2003, 64, 731-740] with slight modifications, including that ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50088224(CHEMBL305346 | E-2-Amino-4-[3-(3-methoxy-phenyl)-a...)
Affinity DataKi:  40nMAssay Description:Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50088196(2-Amino-4-(3-chloro-allyl)-pentanedioic acid | CHE...)
Affinity DataKi:  41nMAssay Description:Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50088217(CHEMBL58095 | E-2-Amino-4-(3-phenyl-allyl)-pentane...)
Affinity DataKi:  44nMAssay Description:Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50088221(CHEMBL293118 | E-2-Amino-4-[3-(3,4-dichloro-phenyl...)
Affinity DataKi:  49nMAssay Description:Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50200526(CHEMBL1234118)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]kainate from human GluK1 expressed in HEK293 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50088200(CHEMBL291491 | E-2-Amino-4-[3-(4-trifluoromethyl-p...)
Affinity DataKi:  52nMAssay Description:Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50091474((2S,4E)-2-amino-4-(2-methylpropylidene)pentanedioi...)
Affinity DataKi:  54nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 1 using cell membranes prepared from HEK293 cell...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50088213((2S,4R)-4-allyl glutamate | 2-Allyl-4-amino-pentan...)
Affinity DataKi:  56nMAssay Description:Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50088199(CHEMBL302680 | E-2-Amino-4-[3-(4-isopropyl-phenyl)...)
Affinity DataKi:  58nMAssay Description:Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50088234(CHEMBL60168 | E-2-Amino-4-[3-(4-nitro-phenyl)-ally...)
Affinity DataKi:  59nMAssay Description:Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50088227(CHEMBL58054 | E-2-Amino-4-[3-(3-chloro-phenyl)-all...)
Affinity DataKi:  60nMAssay Description:Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50091481((S)-2-Amino-4-propylidene-pentanedioicacid | CHEMB...)
Affinity DataKi:  61nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 1 using cell membranes prepared from HEK293 cell...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM141508(US8921370, 171 | US9656975, 171)
Affinity DataKi:  65nMAssay Description:Binding assays were performed as described in [J. A. O'Brien et al. Mol Pharmacol., 2003, 64, 731-740] with slight modifications, including that ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50088205(CHEMBL294683 | E-2-Amino-4-[3-(4-fluoro-phenyl)-al...)
Affinity DataKi:  78nMAssay Description:Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM141502(US8921370, 6 | US9656975, 6)
Affinity DataKi:  78nMAssay Description:Binding assays were performed as described in [J. A. O'Brien et al. Mol Pharmacol., 2003, 64, 731-740] with slight modifications, including that ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50091485((S)-2-Amino-4-butylidene-pentanedioic acid | CHEMB...)
Affinity DataKi:  80nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 1 using cell membranes prepared from HEK293 cell...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50166288((S)-2-Amino-3-[3-hydroxy-5-(2-methyl-2H-tetrazol-5...)
Affinity DataKi:  81nMAssay Description:Binding affinity for kainate Glutamate receptor GluR5 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50091479((S)-2-Amino-4-(2,2-dimethyl-propylidene)-pentanedi...)
Affinity DataKi:  86nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 1 using cell membranes prepared from HEK293 cell...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50494342(CHEMBL3088072)
Affinity DataKi:  90nMAssay Description:Displacement of [3H]ATPA from human Gluk1 receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50091475((2S,4Z)-2-amino-4-(2-methylpropylidene)pentanedioi...)
Affinity DataKi:  94nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 1 using cell membranes prepared from HEK293 cell...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50116040((7-{3-[3-(4-Nitro-phenyl)-ureidomethyl]-pyrrol-1-y...)
Affinity DataKi:  100nMAssay Description:Binding affinity towards cloned human GluR5 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50494350(CHEMBL3088064)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]ATPA from human Gluk1 receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50088230((2S,4R)-4-propylglutamic acid | 2-Amino-4-propyl-p...)
Affinity DataKi:  123nMAssay Description:Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50088198(CHEMBL59297 | E-2-Amino-4-[3-(2,6-dichloro-phenyl)...)
Affinity DataKi:  131nMAssay Description:Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50088232(CHEMBL292896 | E-2-Amino-4-(3-biphenyl-4-yl-allyl)...)
Affinity DataKi:  133nMAssay Description:Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50091478((S)-2-Amino-4-pentylidene-pentanedioicacid | CHEMB...)
Affinity DataKi:  150nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 1 using cell membranes prepared from HEK293 cell...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM50091488((S)-2-Amino-4-[1-cyclopentyl-meth-(E)-ylidene]-pen...)
Affinity DataKi:  152nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 1 using cell membranes prepared from HEK293 cell...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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