Compile Data Set for Download or QSAR
Report error Found 206 of affinity data for UniProtKB/TrEMBL: P78356
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | Vargatef | US10981896, Co...)
Affinity DataKd:  17nMAssay Description:Binding constant for PIP5K2B kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  18nMAssay Description:Binding affinity to PIP5K2BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  18nMAssay Description:Binding constant for PIP5K2B kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50615191(CHEMBL5271804)
Affinity DataIC50: 30nMAssay Description:Inhibition of PI5P4Kbeta (unknown origin) incubated for 1 hr in presence of [33P]gamma-ATP and ATP by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  39nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  39nMAssay Description:Binding constant for PIP5K2B kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  39nMAssay Description:Binding affinity to PIP5K2BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  39nMAssay Description:Binding constant for full-length PIP5K2BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM31096(CHEMBL290084 | Staurosporine | cid_451705 | US2024...)
Affinity DataKd:  77nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  77nMAssay Description:Binding constant for full-length PIP5K2BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  77nMAssay Description:Binding constant for PIP5K2B kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50355496(CHEMBL1908397)
Affinity DataKd:  94nMAssay Description:Binding constant for PIP5K2B kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM13534(VX680 | N-[4-[[4-(4-methylpiperazino)-6-[(5-methyl...)
Affinity DataKd:  140nMAssay Description:Binding constant for PIP5K2B kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM13534(VX680 | N-[4-[[4-(4-methylpiperazino)-6-[(5-methyl...)
Affinity DataKd:  140nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM13534(VX680 | N-[4-[[4-(4-methylpiperazino)-6-[(5-methyl...)
Affinity DataKd:  140nMAssay Description:Binding constant for full-length PIP5K2BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50332294(N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)...)
Affinity DataKd:  160nMAssay Description:Binding constant for PIP5K2B kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd:  260nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd:  260nMAssay Description:Binding constant for PIP5K2B kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd:  260nMAssay Description:Binding constant for full-length PIP5K2BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM25118(4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-...)
Affinity DataKd:  260nMAssay Description:Binding constant for full-length PIP5K2BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM25118(4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-...)
Affinity DataKd:  260nMAssay Description:Binding constant for PIP5K2B kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM25118(4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-...)
Affinity DataKd:  260nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM31094(PKC-412 | cid_24202429)
Affinity DataKd:  270nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50326053(PKC-412 | CHEMBL608533 | US20240132489, Compound S...)
Affinity DataKd:  270nMAssay Description:Binding constant for PIP5K2B kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50326053(PKC-412 | CHEMBL608533 | US20240132489, Compound S...)
Affinity DataKd:  270nMAssay Description:Binding constant for full-length PIP5K2BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50326053(PKC-412 | CHEMBL608533 | US20240132489, Compound S...)
Affinity DataKd:  270nMAssay Description:Binding affinity to PIP5K2BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM17055((9S)-9-[(dimethylamino)methyl]-6,7,10,11-tetrahydr...)
Affinity DataKd:  830nMAssay Description:Binding constant for PIP5K2B kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM17055((9S)-9-[(dimethylamino)methyl]-6,7,10,11-tetrahydr...)
Affinity DataKd:  830nMAssay Description:Binding constant for full-length PIP5K2BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM17055((9S)-9-[(dimethylamino)methyl]-6,7,10,11-tetrahydr...)
Affinity DataKd:  830nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM60665(US9145414, R406 | US9212178, R406 | BDBM50249542 |...)
Affinity DataKd:  1.20E+3nMAssay Description:Binding constant for PIP5K2B kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM6866(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3b ...)
Affinity DataKd:  1.30E+3nMAssay Description:Binding constant for full-length PIP5K2BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM6866(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3b ...)
Affinity DataKd:  1.30E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50242737((R,Z)-5-(2,6-dichlorobenzylsulfonyl)-3-((3,5-dimet...)
Affinity DataKd:  1.60E+3nMAssay Description:Binding constant for PIP5K2B kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50527927(CHEMBL4436648)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of GST-tagged recombinant PI5P4Kbeta (unknown origin) incubated for 1 hr in presence of DPPS and PI5P by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM15138(Biochemistry 469551 Compound 11 | 5-indazolyl pyri...)
Affinity DataKd:  1.70E+3nMAssay Description:Binding constant for PIP5K2B kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50527943(CHEMBL4447308)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of GST-tagged recombinant PI5P4Kbeta (unknown origin) incubated for 1 hr in presence of DPPS and PI5P by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50511409(Imanixil)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human full length PI5P4Kbeta expressed in Escherichia coli BL21(DE3) pre-incubated for 15 mins followed by ATP addition measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM31090((E)-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-etho...)
Affinity DataKd:  2.60E+3nMAssay Description:Binding constant for full-length PIP5K2BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM31090((E)-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-etho...)
Affinity DataKd:  2.60E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50527938(CHEMBL4454033)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of GST-tagged recombinant PI5P4Kbeta (unknown origin) incubated for 1 hr in presence of DPPS and PI5P by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50326054(CHEMBL1240703)
Affinity DataKd:  3.20E+3nMAssay Description:Binding affinity to PIP5K2BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50355499(CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...)
Affinity DataKd:  3.70E+3nMAssay Description:Binding constant for PIP5K2B kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50511409(Imanixil)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of PI5P4Kbeta (unknown origin) incubated for 15 mins in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50527931(CHEMBL4519752)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of GST-tagged recombinant PI5P4Kbeta (unknown origin) incubated for 1 hr in presence of DPPS and PI5P by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50355500(CHEMBL1908394 | US9695172, GSK461364)
Affinity DataKd:  4.50E+3nMAssay Description:Binding constant for PIP5K2B kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50511422(CHEMBL4446338)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of PI5P4Kbeta (unknown origin) incubated for 10 mins in presence of [33P]gamma-ATP and ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50511422(CHEMBL4446338)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of PI5P4Kbeta (unknown origin) incubated for 15 mins in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50511415(CHEMBL4461694)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of PI5P4Kbeta (unknown origin) incubated for 15 mins in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50511414(CHEMBL4472811)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of PI5P4Kbeta (unknown origin) incubated for 15 mins in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM25084(JMC504279 Compound 6 | 3-[2,4-diamino-6-(3-hydroxy...)
Affinity DataKd:  7.80E+3nMAssay Description:Binding constant for PIP5K2B kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
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