Compile Data Set for Download or QSAR
Report error Found 29 for UniProtKB: Q9NR82
LigandPNGBDBM50465779(CHEMBL4278049)
Affinity DataEC50:  80nMAssay Description:Activation of human Kv7.3/7.5 by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50465777(CHEMBL4288707)
Affinity DataEC50:  200nMAssay Description:Activation of human Kv7.3/7.5 by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50465773(CHEMBL4277250)
Affinity DataEC50:  250nMAssay Description:Activation of human Kv7.3/7.5 by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 5(Human)
University Federico Ii of Naples

Curated by ChEMBL
LigandPNGBDBM50526876(CHEMBL4457044)
Affinity DataEC50:  350nMAssay Description:Activation of human Kv7.5 expressed in CHO cells assessed as increase in channel current amplitude by whole cell patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
LigandPNGBDBM50465774(CHEMBL4287894)
Affinity DataEC50:  360nMAssay Description:Activation of human Kv7.3/7.5 by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50465778(CHEMBL4287478)
Affinity DataEC50:  400nMAssay Description:Activation of human Kv7.3/7.5 by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50465775(CHEMBL1703636)
Affinity DataEC50:  500nMAssay Description:Activation of human Kv7.3/7.5 by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 5(Human)
University Federico Ii of Naples

Curated by ChEMBL
LigandPNGBDBM50592360(CHEMBL4549229)
Affinity DataEC50:  540nMAssay Description:Agonist activity at Kv7.5 (unknown origin) expressed in CHO cells co-expressing GFPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 5(Human)
University Federico Ii of Naples

Curated by ChEMBL
LigandPNGBDBM50143558(CHEMBL41355 | N-(2-amino-4-(4-fluorobenzylamino)-p...)
Affinity DataEC50:  800nMAssay Description:Activation of human Kv7.5 expressed in CHO cells assessed as increase in channel current amplitude by whole cell patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 5(Human)
University Federico Ii of Naples

Curated by ChEMBL
LigandPNGBDBM50592357(CHEMBL5185685)
Affinity DataEC50:  1.06E+3nMAssay Description:Agonist activity at Kv7.5 (unknown origin) expressed in CHO cells co-expressing GFPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 5(Human)
University Federico Ii of Naples

Curated by ChEMBL
LigandPNGBDBM50526877(CHEMBL4545892)
Affinity DataEC50:  1.07E+3nMAssay Description:Activation of human Kv7.5 expressed in CHO cells assessed as increase in channel current amplitude by whole cell patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 5(Human)
University Federico Ii of Naples

Curated by ChEMBL
LigandPNGBDBM50521288(CHEMBL4438770)
Affinity DataEC50:  1.37E+3nMAssay Description:Agonist activity at human KCNQ5 expressed in CHOK1 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 5(Human)
University Federico Ii of Naples

Curated by ChEMBL
LigandPNGBDBM50521289(CHEMBL4588394)
Affinity DataEC50:  1.68E+3nMAssay Description:Agonist activity at human KCNQ5 expressed in CHOK1 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 5(Human)
University Federico Ii of Naples

Curated by ChEMBL
LigandPNGBDBM50426567(BMS-204352 | MaxiPost | FLINDOKALNER)
Affinity DataEC50:  2.40E+3nMAssay Description:Positive modulatory activity at voltage-gated K channel 7.5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 5(Human)
University Federico Ii of Naples

Curated by ChEMBL
LigandPNGBDBM50521286(CHEMBL4450214)
Affinity DataEC50:  2.43E+3nMAssay Description:Agonist activity at human KCNQ5 expressed in CHOK1 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 5(Human)
University Federico Ii of Naples

Curated by ChEMBL
LigandPNGBDBM50143558(CHEMBL41355 | N-(2-amino-4-(4-fluorobenzylamino)-p...)
Affinity DataEC50:  3.45E+3nMAssay Description:Agonist activity at human KCNQ5 expressed in CHOK1 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 5(Human)
University Federico Ii of Naples

Curated by ChEMBL
LigandPNGBDBM50592356(CHEMBL4458793)
Affinity DataEC50:  3.78E+3nMAssay Description:Agonist activity at Kv7.5 (unknown origin) expressed in CHO cells co-expressing GFPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 5(Human)
University Federico Ii of Naples

Curated by ChEMBL
LigandPNGBDBM50592355(CHEMBL5200636)
Affinity DataEC50:  3.78E+3nMAssay Description:Agonist activity at Kv7.5 (unknown origin) expressed in CHO cells co-expressing GFPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 5(Human)
University Federico Ii of Naples

Curated by ChEMBL
LigandPNGBDBM50594442(CHEMBL5178988)
Affinity DataEC50:  4.50E+3nMAssay Description:Agonist activity at human KCNQ5 channel expressed in CHO cells assessed as increase in outward current by patch clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
LigandPNGBDBM50420049(CHEMBL402146)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of human Kv7.3/7.5 by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM697213(US20240316020, Example 28 | 1-[[2- (difluoromethox...)
Affinity DataEC50: >3.00E+4nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
Go to US Patent

LigandPNGBDBM697199(US20240316020, Example 14 | BDBM697202 | 1-[[2- (d...)
Affinity DataEC50: >3.00E+4nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
Go to US Patent

LigandPNGBDBM697212(US20240316020, Example 27 | 1-[[2- (difluoromethox...)
Affinity DataEC50: >3.00E+4nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
Go to US Patent

LigandPNGBDBM697210(US20240316020, Example 25 | 1-[[2- (difluoromethox...)
Affinity DataEC50: >3.00E+4nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
Go to US Patent

LigandPNGBDBM697209(US20240316020, Example 24 | 1-[[2- (difluoromethox...)
Affinity DataEC50: >3.00E+4nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
Go to US Patent

LigandPNGBDBM697208(US20240316020, Example 23 | 1-[[2- (difluoromethox...)
Affinity DataEC50: >3.00E+4nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
Go to US Patent

LigandPNGBDBM697206(US20240316020, Example 21 | 1-[[2- (difluoromethox...)
Affinity DataEC50: >3.00E+4nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
Go to US Patent

LigandPNGBDBM697204(US20240316020, Example 19 | 1-[[2- (difluoromethox...)
Affinity DataEC50: >3.00E+4nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
Go to US Patent

LigandPNGBDBM697199(US20240316020, Example 14 | BDBM697202 | 1-[[2- (d...)
Affinity DataEC50: >3.00E+4nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
Go to US Patent