Compile Data Set for Download or QSAR
Report error Found 1156 of affinity data for UniProtKB/TrEMBL: Q9Y2R2
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436357BDBM50436357(CHEMBL2396719)
Affinity DataKi:  110nMAssay Description:Competitive inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 303) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 46247BDBM46247(2-[4-[(E)-[[[4-[2-(4-chloroanilino)-4-thiazolyl]ph...)
Affinity DataIC50: 113nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391109BDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)
Affinity DataIC50: 120nMAssay Description:Inhibition of DOT1L (unknown origin)-mediated H3K79 methylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653726BDBM50653726(CHEMBL6103296)
Affinity DataKi:  140nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436357BDBM50436357(CHEMBL2396719)
Affinity DataIC50: 170nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436358BDBM50436358(CHEMBL2396718)
Affinity DataIC50: 171nMAssay Description:Inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 303) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 46247BDBM46247(2-[4-[(E)-[[[4-[2-(4-chloroanilino)-4-thiazolyl]ph...)
Affinity DataIC50: 249nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653726BDBM50653726(CHEMBL6103296)
Affinity DataIC50: 250nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653716BDBM50653716(CHEMBL6078598)
Affinity DataIC50: 250nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436357BDBM50436357(CHEMBL2396719)
Affinity DataIC50: 250nMAssay Description:Reversible inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 303) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436357BDBM50436357(CHEMBL2396719)
Affinity DataIC50: 259nMAssay Description:Reversible inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 303) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436357BDBM50436357(CHEMBL2396719)
Affinity DataIC50: 259nMAssay Description:Inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 294) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436360BDBM50436360(CHEMBL2396723)
Affinity DataIC50: 259nMAssay Description:Inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 303) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436357BDBM50436357(CHEMBL2396719)
Affinity DataIC50: 259nMAssay Description:Inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 303) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653727BDBM50653727(CHEMBL6133607)
Affinity DataIC50: 260nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436363BDBM50436363(CHEMBL2396720)
Affinity DataIC50: 263nMAssay Description:Inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 303) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50335864BDBM50335864(3-(1-(4-(4-bromonaphthalen-1-ylamino)-4-oxobutyl)-...)
Affinity DataIC50: 270nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653719BDBM50653719(CHEMBL6120825)
Affinity DataIC50: 290nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436364BDBM50436364(CHEMBL2396717)
Affinity DataIC50: 300nMAssay Description:Inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 303) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436364BDBM50436364(CHEMBL2396717)
Affinity DataIC50: 300nMAssay Description:Inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 294) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436362BDBM50436362(CHEMBL2396721)
Affinity DataIC50: 310nMAssay Description:Inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 303) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50335865BDBM50335865(6-Hydroxy-2-(4-methoxyphenyl)-3-(1-(4-(naphthalen-...)
Affinity DataIC50: 340nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50335866BDBM50335866(6-hydroxy-2-(4-methoxyphenyl)-3-(1-(4-(4-nitronaph...)
Affinity DataIC50: 340nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 46247BDBM46247(2-[4-[(E)-[[[4-[2-(4-chloroanilino)-4-thiazolyl]ph...)
Affinity DataIC50: 369nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2011
Entry Details
PCBioAssay
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50335867BDBM50335867(3-(1-(4-(4-Chloronaphthalen-1-ylamino)-4-oxobutyl)...)
Affinity DataIC50: 380nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653730BDBM50653730(CHEMBL6078571)
Affinity DataKi:  380nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50377800BDBM50377800(CHEMBL442448)
Affinity DataIC50: 390nMAssay Description:Inhibition of lymphoid specific tyrosine phosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50335868BDBM50335868(6-Hydroxy-3-(1-(4-(naphthalen-1-ylamino)-4-oxobuty...)
Affinity DataIC50: 410nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653723BDBM50653723(CHEMBL6148148)
Affinity DataIC50: 420nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetTyrosine-protein phosphatase non-receptor type 22 [1-303](Human)
Purdue Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 600532BDBM600532(US11629130, Example 25)
Affinity DataIC50: 430nMAssay Description:Expression and Purification of the LYP Catalytic Domain N-terminal (His)6-tagged LYP catalytic domain (residues 1-303) was subcloned into pET28a. For...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653718BDBM50653718(CHEMBL6103444)
Affinity DataIC50: 430nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653724BDBM50653724(CHEMBL6082988)
Affinity DataIC50: 440nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetTyrosine-protein phosphatase non-receptor type 22 [1-303](Human)
Purdue Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 600540BDBM600540(US11629130, Example 35)
Affinity DataIC50: 470nMAssay Description:Expression and Purification of the LYP Catalytic Domain N-terminal (His)6-tagged LYP catalytic domain (residues 1-303) was subcloned into pET28a. For...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50335869BDBM50335869(6-hydroxy-3-(1-(4-oxo-4-(pyren-1-ylamino)butyl)-1H...)
Affinity DataIC50: 480nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 600514BDBM600514(US11629130, Example 1)
Affinity DataKi:  500nMAssay Description:Agonist activity at human PPARgamma in human U2OS cells by cell based transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653730BDBM50653730(CHEMBL6078571)
Affinity DataIC50: 508nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50335870BDBM50335870(6-Hydroxy-3-(1-(4-(6-methoxybenzo[d]thiazol-2-ylam...)
Affinity DataIC50: 520nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 46247BDBM46247(2-[4-[(E)-[[[4-[2-(4-chloroanilino)-4-thiazolyl]ph...)
Affinity DataIC50: 527nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2011
Entry Details
PCBioAssay
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653714BDBM50653714(CHEMBL6146280)
Affinity DataIC50: 530nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetTyrosine-protein phosphatase non-receptor type 22 [1-303](Human)
Purdue Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 600535BDBM600535(US11629130, Example 30)
Affinity DataIC50: 540nMAssay Description:Expression and Purification of the LYP Catalytic Domain N-terminal (His)6-tagged LYP catalytic domain (residues 1-303) was subcloned into pET28a. For...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653715BDBM50653715(CHEMBL6142357)
Affinity DataIC50: 550nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436361BDBM50436361(CHEMBL2396722)
Affinity DataIC50: 550nMAssay Description:Inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 303) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50335871BDBM50335871(3-(1-(4-(4-chloronaphthalen-1-ylamino)-4-oxobutyl)...)
Affinity DataIC50: 560nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 75324BDBM75324(4-[5-[(Z)-[3-(4-nitrophenyl)-4-oxidanylidene-2-sul...)
Affinity DataIC50: 602nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2011
Entry Details
PCBioAssay
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436367BDBM50436367(CHEMBL2396714)
Affinity DataIC50: 610nMAssay Description:Inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 303) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50335872BDBM50335872(3-(1-(4-(6-fluorobenzo[d]thiazol-2-ylamino)-4-oxob...)
Affinity DataIC50: 610nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 46247BDBM46247(2-[4-[(E)-[[[4-[2-(4-chloroanilino)-4-thiazolyl]ph...)
Affinity DataIC50: 626nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2011
Entry Details
PCBioAssay
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653708BDBM50653708(CHEMBL6133408)
Affinity DataIC50: 630nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425815BDBM50425815(CHEMBL2316908)
Affinity DataIC50: 630nMAssay Description:Inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 303) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425815BDBM50425815(CHEMBL2316908)
Affinity DataIC50: 630nMAssay Description:Inhibition of LYP (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
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