BDBM27708 8-chloro-2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahydropyridin-1-yl]propyl}-3,4-dihydroquinazolin-4-one::CHEMBL251030::quinazolinone analogue, 1d

SMILES: Fc1ccc(cc1)C1=CCN(CCCc2nc3c(Cl)cccc3c(=O)[nH]2)CC1

InChI Key: InChIKey=ACCULLWIBRVLMN-UHFFFAOYSA-N

Data: 10 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 27708   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Human)	BDBM27708 (8-chloro-2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	8.0	23
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Poly [ADP-ribose] polymerase 2 (Mouse)	BDBM27708 (8-chloro-2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	25
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					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Human)	BDBM27708 (8-chloro-2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Human)	BDBM27708 (8-chloro-2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 2 (Human)	BDBM27708 (8-chloro-2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM27708 (8-chloro-2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Human)	BDBM27708 (8-chloro-2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Human)	BDBM27708 (8-chloro-2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Human)	BDBM27708 (8-chloro-2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 2 (Human)	BDBM27708 (8-chloro-2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair