BindingDB PrimarySearch

BDBM50001839 CHEMBL428647::PACLITAXEL::taxol

SMILES: CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](c5ccccc5)NC(=O)c6ccccc6)O)O)OC(=O)c7ccccc7)(CO4)OC(=O)C)O)C)OC(=O)C

InChI Key: InChIKey=RCINICONZNJXQF-UHFFFAOYSA-N

Data: 3 KI 39 IC50 1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 42 hits for monomerid = 50001839
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tubulin beta-3 chain (Human)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	7.70	n/a	n/a	n/a	n/a	n/a	n/a
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Integrin alpha-V/beta-3 (Human)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-dependent translocase ABCB1 (Human)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	5.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-dependent translocase ABCB1 (Human)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	5.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-dependent translocase ABCB1 (Human)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	7.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.68E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.89E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Botulinum neurotoxin type A (Clostridium botulinum)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-dependent translocase ABCB1 (Human)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Genome polyprotein (Hepatitis C virus genotype 1b (isolate Con1) (HCV))	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Fibroblast growth factor receptor 1 (Human)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ABL1 (Human)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier organic anion transporter family member 1B1 (Human)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier organic anion transporter family member 1B3 (Human)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Mer (Human)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Nucleotide-binding oligomerization domain-containing protein 2 (Human)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	7.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 3 (Human)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-dependent translocase ABCB1 bd-vinblastine (Mouse)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.27E+5	n/a	n/a	n/a	n/a	n/a	22.5
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UDP-glucuronosyltransferase 1A1 (Human)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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UDP-glucuronosyltransferase 1A4 (Human)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
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UDP-glucuronosyltransferase 1-6 (Human)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	7.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
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UDP-glucuronosyltransferase 2B7 (Human)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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UDP-glucuronosyltransferase 2B10 (Human)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.44E+4	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 4 (Human)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Co-chaperonin GroES (Escherichia coli)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.14E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 2 (Human)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Reverse transcriptase (Human immunodeficiency virus type 1)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>2.34E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Tubulin beta chain (Pig)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	520	n/a	n/a	n/a	n/a
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ATP-dependent translocase ABCB1 (Human)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tubulin beta-3 chain (Human)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	7.70	n/a	n/a	n/a	n/a	n/a	n/a
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60 kDa heat shock protein, mitochondrial (Human)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Thiosulfate sulfurtransferase (Human)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Co-chaperonin GroES (Escherichia coli)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	5.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Chaperonin GroEL (Escherichia coli)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier organic anion transporter family member 1B1 (Human)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	840	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier organic anion transporter family member 1B3 (Human)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Serum paraoxonase/arylesterase 1 (Human)	BDBM50001839 (CHEMBL428647 \| taxol \| PACLITAXEL) Show SMILES Show InChI	GoogleScholar	UniChem	1.65E+4	n/a	4.20E+4	n/a	n/a	n/a	n/a	10.5	n/a
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