BDBM50301375 3,3',5,5'-tetraiodo-L-thyronine::3,5,3',5'-tetraiodo-L-thyronine::4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-L-phenylalanine::CHEMBL1624::L-T4::L-thyroxine::O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine::levothyroxine

SMILES: N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C(O)=O

InChI Key: InChIKey=XUIIKFGFIJCVMT-UHFFFAOYSA-N

Data: 9 IC50  2 Kd  6 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50301375   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transthyretin (Human)	BDBM50301375 (L-thyroxine | 3,3',5,5'-tetraiodo-L-thyronine | 3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Human)	BDBM50301375 (L-thyroxine | 3,3',5,5'-tetraiodo-L-thyronine | 3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Human)	BDBM50301375 (L-thyroxine | 3,3',5,5'-tetraiodo-L-thyronine | 3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
UDP-glucuronosyltransferase 1A1 (Human)	BDBM50301375 (L-thyroxine | 3,3',5,5'-tetraiodo-L-thyronine | 3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
UDP-glucuronosyltransferase 1A1 (Human)	BDBM50301375 (L-thyroxine | 3,3',5,5'-tetraiodo-L-thyronine | 3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 1 group I member 2 (Human)	BDBM50301375 (L-thyroxine | 3,3',5,5'-tetraiodo-L-thyronine | 3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 1 group I member 2 (Human)	BDBM50301375 (L-thyroxine | 3,3',5,5'-tetraiodo-L-thyronine | 3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.12E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM50301375 (L-thyroxine | 3,3',5,5'-tetraiodo-L-thyronine | 3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.86E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proliferating cell nuclear antigen (Human)	BDBM50301375 (L-thyroxine | 3,3',5,5'-tetraiodo-L-thyronine | 3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Malate dehydrogenase, mitochondrial (Human)	BDBM50301375 (L-thyroxine | 3,3',5,5'-tetraiodo-L-thyronine | 3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.36E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyroid hormone receptor beta (Human)	BDBM50301375 (L-thyroxine | 3,3',5,5'-tetraiodo-L-thyronine | 3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	240	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyroid hormone receptor alpha (Human)	BDBM50301375 (L-thyroxine | 3,3',5,5'-tetraiodo-L-thyronine | 3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Human)	BDBM50301375 (L-thyroxine | 3,3',5,5'-tetraiodo-L-thyronine | 3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	930	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Human)	BDBM50301375 (L-thyroxine | 3,3',5,5'-tetraiodo-L-thyronine | 3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.54E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50301375 (L-thyroxine | 3,3',5,5'-tetraiodo-L-thyronine | 3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50301375 (L-thyroxine | 3,3',5,5'-tetraiodo-L-thyronine | 3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Solute carrier organic anion transporter family member 4C1 (Human)	BDBM50301375 (L-thyroxine | 3,3',5,5'-tetraiodo-L-thyronine | 3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair