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Found 192 with Last Name = 'angusti' and Initial = 'a'
TargetThymidine kinase(Varicella-zoster virus (strain Dumas) (HHV-3) (Hum...)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206491(1-beta-D-arabinofuranosyl-5-(2-bromovinyl)uracil |...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of VZV TK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Varicella-zoster virus (strain Dumas) (HHV-3) (Hum...)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50366680(CHEMBL605255)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibitory concentration against Varicella- zoster virus thymidine kinase(VZV TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Varicella-zoster virus (strain Dumas) (HHV-3) (Hum...)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206497(1-[2'-O-(4-aminobutanoyl)-beta-D-arabinofuranosyl]...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of VZV TK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206491(1-beta-D-arabinofuranosyl-5-(2-bromovinyl)uracil |...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of HSV1 TK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206507(1-[2'-O-(N-Boc-12-aminododecanoyl)-beta-D-arabinof...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of human TK2 assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Universit£

Curated by ChEMBL
LigandPNGBDBM50366680(CHEMBL605255)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibitory concentration against Herpes simplex virus type 1 thymidine kinase(HSV-1 TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50100407(CHEMBL238635 | Octanoic acid 2-[5-((E)-2-bromo-vin...)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibitory concentration against mitochondrial thymidine kinase (TK-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206488((2R,3S,4R,5R)-2-(5-(2-bromovinyl)-2,4-dioxo-3,4-di...)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of human TK2 assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206496(1-[2'-O-(N-boc-8-aminooctanoyl)-beta-D-arabinofura...)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of human TK2 assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50100411(CHEMBL400618 | Decanoic acid 2-[5-((E)-2-bromo-vin...)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibitory concentration against mitochondrial thymidine kinase (TK-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206484((2R,3S,4R,5R)-2-(5-((E)-2-bromovinyl)-2,4-dioxo-3,...)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of human TK2 assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Varicella-zoster virus (strain Dumas) (HHV-3) (Hum...)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50132291(1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-t...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibitory concentration against Varicella- zoster virus thymidine kinase(VZV TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Varicella-zoster virus (strain Dumas) (HHV-3) (Hum...)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50132291(1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-t...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of VZV TK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206497(1-[2'-O-(4-aminobutanoyl)-beta-D-arabinofuranosyl]...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of HSV1 TK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Universit£

Curated by ChEMBL
LigandPNGBDBM50132291(1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-t...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of Rhizopus chinensis pepsin using fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50132291(1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-t...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of HSV1 TK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50100412(BDBM50206505 | CHEMBL392957 | Dodecanoic acid 4-hy...)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of human TK2 assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50100412(BDBM50206505 | CHEMBL392957 | Dodecanoic acid 4-hy...)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibitory concentration against mitochondrial thymidine kinase (TK-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxynucleoside kinase(Drosophila melanogaster)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206491(1-beta-D-arabinofuranosyl-5-(2-bromovinyl)uracil |...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of Drosophila melanogaster dNK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50100409(BDBM50206502 | CHEMBL400410 | Decanoic acid 4-hydr...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibitory concentration against mitochondrial thymidine kinase (TK-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50100409(BDBM50206502 | CHEMBL400410 | Decanoic acid 4-hydr...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of human TK2 assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxynucleoside kinase(Drosophila melanogaster)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50366680(CHEMBL605255)
Affinity DataIC50:  3.16E+4nMAssay Description:Inhibitory concentration against Drosophila melanogaster deoxyribonucleoside kinase (Dm-dNK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Varicella-zoster virus (strain Dumas) (HHV-3) (Hum...)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206483((2R,3S,4R,5R)-2-(5-((E)-2-bromovinyl)-2,4-dioxo-3,...)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of VZV TK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Varicella-zoster virus (strain Dumas) (HHV-3) (Hum...)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50100415(CHEMBL399413 | Methoxy-acetic acid 2-[5-((E)-2-bro...)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibitory concentration against Varicella- zoster virus thymidine kinase(VZV TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Varicella-zoster virus (strain Dumas) (HHV-3) (Hum...)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206495(1-[2'-O-(4-methoxyphenylacetyl)-beta-D-arabinofura...)
Affinity DataIC50:  3.90E+4nMAssay Description:Inhibition of VZV TK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206484((2R,3S,4R,5R)-2-(5-((E)-2-bromovinyl)-2,4-dioxo-3,...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of human fibroblast mitochondrial TK2 using dThd substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50366680(CHEMBL605255)
Affinity DataIC50:  4.30E+4nMAssay Description:Inhibitory concentration against mitochondrial thymidine kinase (TK-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206491(1-beta-D-arabinofuranosyl-5-(2-bromovinyl)uracil |...)
Affinity DataIC50:  4.30E+4nMAssay Description:Inhibition of human TK2 assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206495(1-[2'-O-(4-methoxyphenylacetyl)-beta-D-arabinofura...)
Affinity DataIC50:  4.40E+4nMAssay Description:Inhibition of human TK2 assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206498(1-[2'-O-(N-boc-4-aminobutanoyl)-beta-D-arabinofura...)
Affinity DataIC50:  5.50E+4nMAssay Description:Inhibition of human TK2 assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206493(1-[2'-O-(N-boc-6-aminohexanoyl)-beta-D-arabinofura...)
Affinity DataIC50:  6.10E+4nMAssay Description:Inhibition of human TK2 assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxynucleoside kinase(Drosophila melanogaster)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50132291(1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-t...)
Affinity DataIC50:  6.50E+4nMAssay Description:Inhibitory concentration against Drosophila melanogaster deoxyribonucleoside kinase (Dm-dNK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxynucleoside kinase(Drosophila melanogaster)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50132291(1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-t...)
Affinity DataIC50:  6.50E+4nMAssay Description:Inhibition of Drosophila melanogaster dNK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206495(1-[2'-O-(4-methoxyphenylacetyl)-beta-D-arabinofura...)
Affinity DataIC50:  6.80E+4nMAssay Description:Inhibition of HSV1 TK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxynucleoside kinase(Drosophila melanogaster)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206496(1-[2'-O-(N-boc-8-aminooctanoyl)-beta-D-arabinofura...)
Affinity DataIC50:  7.40E+4nMAssay Description:Inhibition of Drosophila melanogaster dNK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206508(1-(2'-O-phenylacetyl-beta-D-arabinofuranosyl)-5(E)...)
Affinity DataIC50:  7.40E+4nMAssay Description:Inhibition of human TK2 assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxynucleoside kinase(Drosophila melanogaster)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206493(1-[2'-O-(N-boc-6-aminohexanoyl)-beta-D-arabinofura...)
Affinity DataIC50:  7.70E+4nMAssay Description:Inhibition of Drosophila melanogaster dNK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Universit£

Curated by ChEMBL
LigandPNGBDBM50100415(CHEMBL399413 | Methoxy-acetic acid 2-[5-((E)-2-bro...)
Affinity DataIC50:  8.40E+4nMAssay Description:Inhibitory concentration against Herpes simplex virus type 1 thymidine kinase(HSV-1 TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206483((2R,3S,4R,5R)-2-(5-((E)-2-bromovinyl)-2,4-dioxo-3,...)
Affinity DataIC50:  8.40E+4nMAssay Description:Inhibition of HSV1 TK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Varicella-zoster virus (strain Dumas) (HHV-3) (Hum...)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206492(1-[2'-O-(6-aminohexanoyl)-beta-D-arabinofuranosyl]...)
Affinity DataIC50:  9.40E+4nMAssay Description:Inhibition of VZV TK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206484((2R,3S,4R,5R)-2-(5-((E)-2-bromovinyl)-2,4-dioxo-3,...)
Affinity DataIC50:  9.70E+4nMAssay Description:Inhibition of human fibroblast mitochondrial TK2 using dCyd substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206494(1-(2'-O-octanoyl-beta-D-arabinofuranosyl)thymine |...)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibition of human TK2 assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50100414(1-(4-Hydroxy-5-hydroxymethyl-3-octyloxy-tetrahydro...)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibitory concentration against mitochondrial thymidine kinase (TK-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50100414(1-(4-Hydroxy-5-hydroxymethyl-3-octyloxy-tetrahydro...)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibition of human TK2 assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Varicella-zoster virus (strain Dumas) (HHV-3) (Hum...)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206498(1-[2'-O-(N-boc-4-aminobutanoyl)-beta-D-arabinofura...)
Affinity DataIC50:  1.30E+5nMAssay Description:Inhibition of VZV TK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol kinase 1(Drosophila melanogaster)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206506(9-beta-D-arabinofuranosylguanosine | CHEMBL240933)
Affinity DataIC50:  1.33E+5nMAssay Description:Inhibition of Drosophila melanogaster dGK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxynucleoside kinase(Drosophila melanogaster)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206498(1-[2'-O-(N-boc-4-aminobutanoyl)-beta-D-arabinofura...)
Affinity DataIC50:  1.33E+5nMAssay Description:Inhibition of Drosophila melanogaster dNK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxynucleoside kinase(Drosophila melanogaster)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206497(1-[2'-O-(4-aminobutanoyl)-beta-D-arabinofuranosyl]...)
Affinity DataIC50:  1.60E+5nMAssay Description:Inhibition of Drosophila melanogaster dNK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxynucleoside kinase(Drosophila melanogaster)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206484((2R,3S,4R,5R)-2-(5-((E)-2-bromovinyl)-2,4-dioxo-3,...)
Affinity DataIC50:  1.63E+5nMAssay Description:Inhibition of Drosophila melanogaster dNK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxynucleoside kinase(Drosophila melanogaster)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50100411(CHEMBL400618 | Decanoic acid 2-[5-((E)-2-bromo-vin...)
Affinity DataIC50:  1.63E+5nMAssay Description:Inhibitory concentration against Drosophila melanogaster deoxyribonucleoside kinase (Dm-dNK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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