TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: <0.100nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: <0.100nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: <0.100nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: <0.100nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: <0.100nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 0.370nMAssay Description:Enzyme assay using full length recombinant active form of wild-type BTK and BTK-C481S was measured as described previously (Anastassiadis T, et al., ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 0.390nMAssay Description:Enzyme assay using full length recombinant active form of wild-type BTK and BTK-C481S was measured as described previously (Anastassiadis T, et al., ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 0.430nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 0.550nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 0.550nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 0.550nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 0.550nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 0.550nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 0.550nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 0.550nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 0.550nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 0.550nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 0.550nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 0.550nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 0.550nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 0.550nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 0.550nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 0.550nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 0.570nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 0.580nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 0.580nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 0.600nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 0.660nMAssay Description:The kinase activity of BTK (C481S) was assayed at Reaction Biology Corporation. The substrate in the BTK (C481S) reaction, pEY (poly[Glu:Tyr] (4:1)) ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 0.700nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 0.760nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 0.780nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 0.790nMAssay Description:Enzyme assay using full length recombinant active form of wild-type BTK and BTK-C481S was measured as described previously (Anastassiadis T, et al., ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 0.820nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 0.860nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 0.900nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 0.930nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 0.950nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 0.990nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 0.990nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 0.990nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 1.03nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 1.06nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 1.10nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 1.49nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 1.5nMAssay Description:The kinase activity of BTK (C481S) was assayed at Reaction Biology Corporation. The substrate in the BTK (C481S) reaction, pEY (poly[Glu:Tyr] (4:1)) ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 1.60nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 1.70nMAssay Description:The specific assay process of BTK enzyme activity assay is as follows: Buffer: 20 mM 2-[4-(2-hydroxyethyl)-1-piperazinyl]ethanesulfonic acid (Hepes) ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: 1.72nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: <5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)
US Patent
Transthera Sciences (Nanjing)
US Patent
Affinity DataIC50: <5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair