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Found 563 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK [C481S]'
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM568360(US11420975, Compound A-10-13)
Affinity DataIC50: <0.100nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM568357(US11420975, Compound A-10-10)
Affinity DataIC50: <0.100nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM568356(US11420975, Compound A-10-8)
Affinity DataIC50: <0.100nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM568354(US11420975, Compound A-10-6)
Affinity DataIC50: <0.100nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM568353(US11420975, Compound A-10-5)
Affinity DataIC50: <0.100nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM499813((2-chloro-4-phenoxyphenyl)(4- (((3R,6R)-6-(hydroxy...)
Affinity DataIC50:  0.370nMAssay Description:Enzyme assay using full length recombinant active form of wild-type BTK and BTK-C481S was measured as described previously (Anastassiadis T, et al., ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM499811(US11020398, Compound I-123 | US20230364079, Exampl...)
Affinity DataIC50:  0.390nMAssay Description:Enzyme assay using full length recombinant active form of wild-type BTK and BTK-C481S was measured as described previously (Anastassiadis T, et al., ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM465733(2-[3-(2-amino-6-{4-[(4-methylpiperazin- 1-yl)methy...)
Affinity DataIC50:  0.430nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM568345(US11420975, Compound A-7-2)
Affinity DataIC50:  0.550nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM568383(US11420975, Compound C-7-2)
Affinity DataIC50:  0.550nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM568370(US11420975, Compound A-13-2)
Affinity DataIC50:  0.550nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM568362(US11420975, Compound A-10-15)
Affinity DataIC50:  0.550nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM568361(US11420975, Compound A-10-14)
Affinity DataIC50:  0.550nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM568359(US11420975, Compound A-10-12)
Affinity DataIC50:  0.550nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM568358(US11420975, Compound A-10-11)
Affinity DataIC50:  0.550nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM568355(US11420975, Compound A-10-7)
Affinity DataIC50:  0.550nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM568352(US11420975, Compound A-10-3)
Affinity DataIC50:  0.550nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM568351(US11420975, Compound A-10-1)
Affinity DataIC50:  0.550nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM568350(US11420975, Compound A-7-14)
Affinity DataIC50:  0.550nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM568349(US11420975, Compound A-7-12)
Affinity DataIC50:  0.550nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM568348(US11420975, Compound A-7-9)
Affinity DataIC50:  0.550nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM568347(US11420975, Compound A-7-5)
Affinity DataIC50:  0.550nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM568346(US11420975, Compound A-7-3)
Affinity DataIC50:  0.550nMAssay Description:The substrate solution was prepared by adding the substrate poly(Glu, Tyr) sodium salt (Sigma Aldrich, St. Louis, Mo.) to the substrate reaction buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM468311(2-{3-[2-amino-6-(4- {[4-(2-hydroxy- ethyl)piperazi...)
Affinity DataIC50:  0.570nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM468314(2-{3-[2-amino-6- (1,1-dioxido-3,6- dihydro-2H- thi...)
Affinity DataIC50:  0.580nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM468313(2-(3-{2-amino-6- [1-(4-methylpiperazine-1- carbony...)
Affinity DataIC50:  0.580nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM465738(2-{3-[2-amino-6-(1-methyl-1H-pyrazol- 4-yl)-7H-pyr...)
Affinity DataIC50:  0.600nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM642374(N-(((2S,5R)-5-((5-fluoro-3-(2-fluoro-4- (2-fluorop...)
Affinity DataIC50:  0.660nMAssay Description:The kinase activity of BTK (C481S) was assayed at Reaction Biology Corporation. The substrate in the BTK (C481S) reaction, pEY (poly[Glu:Tyr] (4:1)) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM468318(2-(3-{2-amino-6-[1- (methylsulfonyl)- 1,2,3,6- tet...)
Affinity DataIC50:  0.700nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM468308(2-[3-(2-amino-6-{4- [(diethyl- amino)methyl]phenyl...)
Affinity DataIC50:  0.760nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM468307(2-[3-(2-amino-6-{4- [(dimethyl- amino)methyl]pheny...)
Affinity DataIC50:  0.780nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM499814((2-chloro-4-phenoxyphenyl)(4- (((3S,6S)-6-(hydroxy...)
Affinity DataIC50:  0.790nMAssay Description:Enzyme assay using full length recombinant active form of wild-type BTK and BTK-C481S was measured as described previously (Anastassiadis T, et al., ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM468315(2-{3-[2-amino-6- (1-propionyl-1,2,3,6- tetrahydrop...)
Affinity DataIC50:  0.820nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM468310(2-(3-{2-amino-6-[4- (piperidin-1- ylmethyl)phenyl]...)
Affinity DataIC50:  0.860nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM468309(2-(3-{2-amino-6-[4- (pyrrolidin-1- ylmethyl)phenyl...)
Affinity DataIC50:  0.900nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM468312(2-[3-(2-amino-6-{4- [(3-oxopiperazin-1- yl)methyl]...)
Affinity DataIC50:  0.930nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM468316(4-{2-amino-4-[3- (6-cyclopropyl-8- fluoro-1-oxoiso...)
Affinity DataIC50:  0.950nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM468320(2-{3-[2-amino-6-(1,2,3,6- tetrahydropyridin-4-yl)-...)
Affinity DataIC50:  0.990nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM465748(2-(3-{2-amino-6-[1-(oxetan-3-yl)-1,2,3,6-tetrahydr...)
Affinity DataIC50:  0.990nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM465727(2-[3-(2-amino-8-phenyl-9H-purin-6-yl)-2-(hydroxyme...)
Affinity DataIC50:  0.990nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM465766(2-(3-{2-amino-6-[4- (methylsulfonyl)phenyl]- 7H-py...)
Affinity DataIC50:  1.03nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM465767(2-{3-[2-amino-6-(6- fluoropyridin-2-yl)-7H- pyrrol...)
Affinity DataIC50:  1.06nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM468319(2-{3-[2-amino-6-(1- ethyl-1,2,3,6- tetrahydropyrid...)
Affinity DataIC50:  1.10nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM468317(2-(3-{2-amino-6-[1- (pyrrolidine-1-carbonyl)- 1,2,...)
Affinity DataIC50:  1.49nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM642373(N-(((2S,5R)-5-((3-(4-(2,6-difluorophenoxy)-2-fluor...)
Affinity DataIC50:  1.5nMAssay Description:The kinase activity of BTK (C481S) was assayed at Reaction Biology Corporation. The substrate in the BTK (C481S) reaction, pEY (poly[Glu:Tyr] (4:1)) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM468306(2-(3-{2-amino-6-[2- (methylamino)pyridin- 4-yl]-7H...)
Affinity DataIC50:  1.60nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM634110(US20230357248, Example 1)
Affinity DataIC50:  1.70nMAssay Description:The specific assay process of BTK enzyme activity assay is as follows: Buffer: 20 mM 2-[4-(2-hydroxyethyl)-1-piperazinyl]ethanesulfonic acid (Hepes) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM465768(2-{3-[2-amino-6-(2- fluoropyridin-4-yl)-7H- pyrrol...)
Affinity DataIC50:  1.72nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM635677(US20230364079, Example 111)
Affinity DataIC50: <5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Transthera Sciences (Nanjing)

US Patent
LigandPNGBDBM635691(US20230364079, Example 118)
Affinity DataIC50: <5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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