Compile Data Set for Download or QSAR
Report error Found 92 of affinity data for UniProtKB/TrEMBL: O19045
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 12751BDBM12751(CHEMBL152854 | 1-(3-carbamimidoylphenyl)-3-methyl-...)
Affinity DataKi:  0.0300nMAssay Description:Binding affinity towards Rabbit Coagulation factor X in a rabbit arterio-venous (A-V) shunt modelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50097625BDBM50097625(4-(3-Carbamimidoyl-phenyl)-2-methyl-thiazole-5-car...)
Affinity DataKi:  0.0800nMAssay Description:Binding affinity towards Rabbit Coagulation factor X in a rabbit arterio-venous (A-V) shunt modelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266924BDBM50266924((2R,4S)-N1-(4-Chlorophenyl)-4-(2,4-difluorophenyl)...)
Affinity DataIC50: 0.108nMAssay Description:Inhibition of rabbit F10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50079240BDBM50079240(CHEMBL93210 | CHEMBL7651 | 3-(3-Carbamimidoyl-phen...)
Affinity DataKi:  0.110nMAssay Description:Inhibitory activity against Rabbit factor Xa was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50087533BDBM50087533(CHEMBL140072 | CHEMBL153611 | 3-(3-Carbamimidoyl-p...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity towards Rabbit Coagulation factor X in a rabbit arterio-venous (A-V) shunt modelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50087533BDBM50087533(CHEMBL140072 | CHEMBL153611 | 3-(3-Carbamimidoyl-p...)
Affinity DataKi:  0.400nMAssay Description:Inhibitory activity against rabbit Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50072442BDBM50072442({(3-Carbamimidoyl-phenyl)-[2-(2'-sulfamoyl-bipheny...)
Affinity DataKi:  0.530nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50087538BDBM50087538((4S,5S)-3-(3-Carbamimidoyl-phenyl)-5-methoxymethyl...)
Affinity DataKi:  0.640nMAssay Description:Inhibitory activity against rabbit Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50079252BDBM50079252(CHEMBL328298 | CHEMBL350499 | 3-(3-Carbamimidoyl-p...)
Affinity DataKi:  0.800nMAssay Description:Inhibitory activity against rabbit Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50072448BDBM50072448({(3-Carbamimidoyl-phenyl)-[3-(2'-sulfamoyl-bipheny...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 35743BDBM35743(CHEMBL479863 | cis-1,2-diaminocyclohexane derivati...)
Affinity DataKi:  1.74nMAssay Description:Inhibition of rabbit factor 10a by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50072444BDBM50072444({(3-Carbamimidoyl-phenyl)-[2-(2'-sulfamoyl-bipheny...)
Affinity DataKi:  2.10nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50125242BDBM50125242(3-(3-Amino-4-chloro-phenyl)-5-(methanesulfonylamin...)
Affinity DataKi:  2.30nMAssay Description:Inhibitory activity against Rabbit factor Xa was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50324743BDBM50324743((3R,4R)-1-(2,2-DIFLUORO-ETHYL)-PYRROLIDINE-3,4-DIC...)
Affinity DataKi:  3.30nMAssay Description:Binding affinity to rabbit factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50125243BDBM50125243(3-(3-Amino-4-chloro-phenyl)-5-ureidomethyl-4,5-dih...)
Affinity DataKi:  4.70nMAssay Description:Inhibitory activity against Rabbit factor Xa was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50072445BDBM50072445(CHEMBL139063 | CHEMBL279628 | [3-(3-Carbamimidoyl-...)
Affinity DataKi:  6.30nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50072435BDBM50072435({(3-Carbamimidoyl-phenyl)-[3-(2'-sulfamoyl-bipheny...)
Affinity DataKi:  6.70nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50072434BDBM50072434({(3-Carbamimidoyl-phenyl)-[3-(2'-sulfamoyl-bipheny...)
Affinity DataKi:  7.5nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50072437BDBM50072437({(3-Carbamimidoyl-phenyl)-[2-(2'-sulfamoyl-bipheny...)
Affinity DataKi:  10nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50072440BDBM50072440(3-{(2-Methoxy-ethyl)-[3-(2'-sulfamoyl-biphenyl-4-y...)
Affinity DataKi:  11nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50072449BDBM50072449({(3-Carbamimidoyl-phenyl)-[3-(2'-sulfamoyl-bipheny...)
Affinity DataKi:  12nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50072450BDBM50072450(3-{(2-Oxo-propyl)-[3-(2'-sulfamoyl-biphenyl-4-yl)-...)
Affinity DataKi:  16nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50072436BDBM50072436(3-{(2-Phenoxy-ethyl)-[3-(2'-sulfamoyl-biphenyl-4-y...)
Affinity DataKi:  16nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50324745BDBM50324745((3R,4R)-methyl 3-(5-chloropyridin-2-ylcarbamoyl)-4...)
Affinity DataKi:  17nMAssay Description:Binding affinity to rabbit factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50072438BDBM50072438(3-{(2-Hydroxy-ethyl)-[3-(2'-sulfamoyl-biphenyl-4-y...)
Affinity DataKi:  17nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50072446BDBM50072446(2-{(3-Carbamimidoyl-phenyl)-[3-(2'-sulfamoyl-biphe...)
Affinity DataKi:  19nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50072439BDBM50072439({(3-Carbamimidoyl-phenyl)-[2-(2'-sulfamoyl-bipheny...)
Affinity DataKi:  21nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50062035BDBM50062035(5-(4-Carbamimidoyl-phenyl)-3-(3-carbamimidoyl-phen...)
Affinity DataKi:  34nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50072433BDBM50072433({(3-Carbamimidoyl-phenyl)-[2-(2'-sulfamoyl-bipheny...)
Affinity DataKi:  37nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 17283BDBM17283((2S)-3-(7-carbamimidoylnaphthalen-2-yl)-2-(4-{[(3S...)
Affinity DataIC50: 41nMAssay Description:Compound was tested for the inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50072447BDBM50072447(3-[2-(2'-Sulfamoyl-biphenyl-4-yl)-ethanesulfonylam...)
Affinity DataKi:  51nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50072443BDBM50072443(3-[3-(2'-Sulfamoyl-biphenyl-4-yl)-propylamino]-ben...)
Affinity DataKi:  83nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50072441BDBM50072441(CHEMBL323060 | CHEMBL92988 | [3-(3-Carbamimidoyl-p...)
Affinity DataKi:  94nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080132BDBM50080132(CHEMBL3415976)
Affinity DataIC50: 460nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of prothombin timeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 7840BDBM7840(Xarelto | RIVAROXABAN | US8822458, 97 | US8822458,...)
Affinity DataIC50: 510nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of prothombin timeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080107BDBM50080107(CHEMBL3415998)
Affinity DataIC50: 720nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of prothombin timeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080132BDBM50080132(CHEMBL3415976)
Affinity DataIC50: 750nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of activated partial thromboplastin timeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080131BDBM50080131(CHEMBL3415975)
Affinity DataIC50: 780nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of prothombin timeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080133BDBM50080133(CHEMBL3415977)
Affinity DataIC50: 810nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of prothombin timeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080143BDBM50080143(CHEMBL3415984)
Affinity DataIC50: 820nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of prothombin timeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 7840BDBM7840(Xarelto | RIVAROXABAN | US8822458, 97 | US8822458,...)
Affinity DataIC50: 860nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of activated partial thromboplastin timeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080101BDBM50080101(CHEMBL3415997)
Affinity DataIC50: 890nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of prothombin timeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080142BDBM50080142(CHEMBL3415983)
Affinity DataIC50: 910nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of prothombin timeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080100BDBM50080100(CHEMBL3415996)
Affinity DataIC50: 920nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of prothombin timeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080107BDBM50080107(CHEMBL3415998)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of activated partial thromboplastin timeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080143BDBM50080143(CHEMBL3415984)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of activated partial thromboplastin timeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080101BDBM50080101(CHEMBL3415997)
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of activated partial thromboplastin timeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080100BDBM50080100(CHEMBL3415996)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of activated partial thromboplastin timeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080131BDBM50080131(CHEMBL3415975)
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of activated partial thromboplastin timeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080133BDBM50080133(CHEMBL3415977)
Affinity DataIC50: 1.52E+3nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of activated partial thromboplastin timeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
Displayed 1 to 50 (of 92 total ) | Next | Last >>
Jump to: