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Report error Found 51 for UniProtKB: P05023
TargetSodium/potassium-transporting ATPase subunit alpha-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652792BDBM50652792(CHEMBL3752910)
Affinity DataKd:  6.80nMAssay Description:Binding affinity to human ATP1A1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 444975BDBM444975(US10668094, Compound DtxMcP-(cyclic) | US10668094,...)
Affinity DataKi:  25nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 444840BDBM444840(US10668094, Compound DtxcB-(cyclic) | US10668094, ...)
Affinity DataKi:  30.7nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 444991BDBM444991(US10668094, Compound DMDMcB-(cyclic))
Affinity DataKi:  31.6nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 231661BDBM231661(DEt (12) | US10668094, Compound DEt)
Affinity DataKi:  53nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 444983BDBM444983(US10668094, Compound DBz-(cyclic))
Affinity DataKi:  57.9nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 231659BDBM231659(DEtDA (10))
Affinity DataKi:  69nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 444984BDBM444984(US10668094, Compound DcH-(cyclic))
Affinity DataKi:  70.4nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 444994BDBM444994(US10668094, Compound DTMS-(silyl))
Affinity DataKi:  72.6nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 231664BDBM231664(DbisGly (14))
Affinity DataKi:  80nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 444981BDBM444981(US10668094, Compound DEcP-(cyclic))
Affinity DataKi:  86.1nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 444989BDBM444989(US10668094, Compound DP)
Affinity DataKi:  87.7nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 46356BDBM46356(SMR000058529 | cid_441207 | MLS000069787 | DIGITOX...)
Affinity DataKi:  89nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 444977BDBM444977(US10668094, Compound DiB)
Affinity DataKi:  92nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 444975BDBM444975(US10668094, Compound DtxMcP-(cyclic) | US10668094,...)
Affinity DataKi:  95.8nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 50286739BDBM50286739(4-[1,5,11,14-Tetrahydroxy-10-hydroxymethyl-13-meth...)
Affinity DataKi:  97nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 231660BDBM231660(DMe (11) | US10668094, Compound DMe)
Affinity DataKi:  101nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 231657BDBM231657(DSCar (8))
Affinity DataKi:  102nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 231660BDBM231660(DMe (11) | US10668094, Compound DMe)
Affinity DataKi:  103nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 444980BDBM444980(US10668094, Compound DcP-(cyclic))
Affinity DataKi:  109nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 231662BDBM231662(DMeCF3 (13) | US10668094, Compound DCF3)
Affinity DataKi:  119nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 231651BDBM231651(DGly (2))
Affinity DataKi:  124nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 444990BDBM444990(US10668094, Compound DtB)
Affinity DataKi:  135nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 444840BDBM444840(US10668094, Compound DtxcB-(cyclic) | US10668094, ...)
Affinity DataKi:  135nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent

TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 444840BDBM444840(US10668094, Compound DtxcB-(cyclic) | US10668094, ...)
Affinity DataKi:  135nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 444996BDBM444996(US10668094, Compound DcPe-(cyclic))
Affinity DataKi:  138nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 231661BDBM231661(DEt (12) | US10668094, Compound DEt)
Affinity DataKi:  138nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 225707BDBM225707(CS337 | Digoxigenin)
Affinity DataKi:  139nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 444979BDBM444979(US10668094, Compound DiP)
Affinity DataKi:  149nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 231653BDBM231653(DGlyN (4))
Affinity DataKi:  152nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 46355BDBM46355(MLS000069819 | cid_2724385 | SMR000059217 | DIGOXI...)
Affinity DataKi:  189nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 231663BDBM231663(Digoxigenin bis-digitoxoside | Dbis)
Affinity DataKi:  196nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 231662BDBM231662(DMeCF3 (13) | US10668094, Compound DCF3)
Affinity DataKi:  199nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 231654BDBM231654(DAlaN (5))
Affinity DataKi:  232nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 231656BDBM231656(DSerN (7))
Affinity DataKi:  242nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 231658BDBM231658(DPrN (9))
Affinity DataKi:  249nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 46355BDBM46355(MLS000069819 | cid_2724385 | SMR000059217 | DIGOXI...)
Affinity DataKi:  268nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetSodium/potassium-transporting ATPase subunit alpha-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 46355BDBM46355(MLS000069819 | cid_2724385 | SMR000059217 | DIGOXI...)
Affinity DataIC50: 290nMAssay Description:Inhibition of human kidney Na(+)/K(+) ATPase alpha-1 assessed as amount of Pi release after 1 hr by colorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 444978BDBM444978(US10668094, Compound DESA-(sulfonamide))
Affinity DataKi:  301nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 231650BDBM231650(DOH (1))
Affinity DataKi:  311nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 231655BDBM231655(DSer (6))
Affinity DataKi:  316nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50096255BDBM50096255(CHEMBL3594278)
Affinity DataIC50: 340nMAssay Description:Inhibition of human kidney Na(+)/K(+) ATPase alpha-1 assessed as amount of Pi release after 1 hr by colorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 444976BDBM444976(US10668094, Compound DESM-(sulfonyl))
Affinity DataKi:  464nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 231652BDBM231652(DGlMe (3))
Affinity DataKi:  540nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652793BDBM50652793(CHEMBL5653589)
Affinity DataKd:  553nMAssay Description:Binding affinity to human ATP1A1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50096254BDBM50096254(CHEMBL3594276)
Affinity DataIC50: 570nMAssay Description:Inhibition of human kidney Na(+)/K(+) ATPase alpha-1 assessed as amount of Pi release after 1 hr by colorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 444982BDBM444982(US10668094, Compound DMSM-(sulfonyl))
Affinity DataKi:  944nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 510514BDBM510514(US11077128, Compound BisAcDcB)
Affinity DataKi:  1.18E+3nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent

TargetSodium/potassium-transporting ATPase subunit alpha-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50096256BDBM50096256(CHEMBL3594279)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of human kidney Na(+)/K(+) ATPase alpha-1 assessed as amount of Pi release after 1 hr by colorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50096257BDBM50096257(CHEMBL3594280)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human kidney Na(+)/K(+) ATPase alpha-1 assessed as amount of Pi release after 1 hr by colorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed
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