Compile Data Set for Download or QSAR
Report error Found 197 of affinity data for UniProtKB/TrEMBL: P23204
LigandPNGBDBM50171900((S)-3-Phenyl-2-(4-thiophen-2-yl-phenoxy)-propionic...)
Affinity DataEC50:  0.150nMAssay Description:Effective concentration against murine PPARalpha in transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM28759(CHEMBL191275 | (2S)-3-phenyl-2-(4-phenylphenoxy)pr...)
Affinity DataEC50:  0.200nMAssay Description:Effective concentration against murine PPARalpha in transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50171898((S)-3-Phenyl-2-(4-trifluoromethyl-phenoxy)-propion...)
Affinity DataEC50:  0.270nMAssay Description:Effective concentration against murine PPARalpha in transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50171895((2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid | (...)
Affinity DataEC50:  0.350nMAssay Description:Effective concentration against murine PPARalpha in transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50099491(cid_3392731 | CHEMBL21241 | 2-(4-{2-[3-Cyclohexyl-...)
Affinity DataEC50:  1nMAssay Description:Activation of murine PPAR alpha ligand binding domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50171897((S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid | (...)
Affinity DataEC50:  1.30nMAssay Description:Effective concentration against murine PPARalpha in transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50229206(N-(4-(trifluoromethylsulfonamido)benzyl)-4-methyl-...)
Affinity DataEC50:  2nMAssay Description:Agonist activity at mouse PPARalpha assessed as receptor activation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
LigandPNGBDBM50568096(CHEMBL4866115)
Affinity DataEC50:  3nMAssay Description:Agonist activity at Gal4-fused mouse PPARalpha co-expressed with RXRalpha in monkey CV1 cells assessed as PPRE transcriptional activation incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandPNGBDBM50568100(CHEMBL4861761)
Affinity DataEC50:  3nMAssay Description:Agonist activity at Gal4-fused mouse PPARalpha co-expressed with RXRalpha in monkey CV1 cells assessed as PPRE transcriptional activation incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandPNGBDBM28799(2-{[4-(2-{[(2,4-difluorophenyl)carbamoyl](heptyl)a...)
Affinity DataEC50:  5nMAssay Description:Agonist activity for murine PPAR alpha receptor in transcriptional activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM28799(2-{[4-(2-{[(2,4-difluorophenyl)carbamoyl](heptyl)a...)
Affinity DataEC50:  5nMAssay Description:Compound was tested for its agonist activity against murine Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor transfected CV-1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50568097(CHEMBL4879102)
Affinity DataEC50:  10nMAssay Description:Agonist activity at Gal4-fused mouse PPARalpha co-expressed with RXRalpha in monkey CV1 cells assessed as PPRE transcriptional activation incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandPNGBDBM28799(2-{[4-(2-{[(2,4-difluorophenyl)carbamoyl](heptyl)a...)
Affinity DataEC50:  10nMAssay Description:Agonist activity at Gal4-fused mouse PPARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50568102(CHEMBL4847453)
Affinity DataEC50:  10nMAssay Description:Agonist activity at Gal4-fused mouse PPARalpha co-expressed with RXRalpha in monkey CV1 cells assessed as PPRE transcriptional activation incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandPNGBDBM50081223(2-(4-{2-[3-(2,4-Difluoro-phenyl)-1-heptyl-ureido]-...)
Affinity DataEC50:  10nMAssay Description:Compound was tested for its agonist activity against murine Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor transfected CV-1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50584465(CHEMBL5084377)
Affinity DataEC50:  17nMAssay Description:Agonist activity at mouse PPARalpha transfected in Cos7 cells co-expressing with pBIND and pGL4.35 Gal4 UAS Luc reporter plasmid by measuring lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
LigandPNGBDBM50229219(4'-chloro-biphenyl-4-carboxylic acid 4-trifluorome...)
Affinity DataEC50:  20nMAssay Description:Agonist activity at mouse PPARalpha assessed as receptor activation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
LigandPNGBDBM50568098(CHEMBL4877444)
Affinity DataEC50:  20nMAssay Description:Agonist activity at Gal4-fused mouse PPARalpha co-expressed with RXRalpha in monkey CV1 cells assessed as PPRE transcriptional activation incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandPNGBDBM50319262(2-(4-(((2-(2,4-dimethylphenylamino)-2-oxoethyl)(fu...)
Affinity DataEC50:  20nMAssay Description:Agonist activity at Gal4-fused mouse PPARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50568103(CHEMBL4847989)
Affinity DataEC50:  20nMAssay Description:Agonist activity at Gal4-fused mouse PPARalpha co-expressed with RXRalpha in monkey CV1 cells assessed as PPRE transcriptional activation incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandPNGBDBM28706(CHEMBL219586 | 2-methyl-2-{4-[({4-methyl-2-[4-(tri...)
Affinity DataEC50:  20nMAssay Description:Agonist activity at mouse PPARalpha assessed as receptor activation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
LigandPNGBDBM50568099(CHEMBL4855604)
Affinity DataEC50:  20nMAssay Description:Agonist activity at Gal4-fused mouse PPARalpha co-expressed with RXRalpha in monkey CV1 cells assessed as PPRE transcriptional activation incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandPNGBDBM50244809((2R)-2-[3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(triflu...)
Affinity DataEC50:  28nMAssay Description:Agonist activity at mouse PPARalpha receptor expressed in african green monkey COS1 cells co-transfected with fused yeast Gal4-DBD by transactivation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
LigandPNGBDBM50568101(CHEMBL4870407)
Affinity DataEC50:  30nMAssay Description:Agonist activity at Gal4-fused mouse PPARalpha co-expressed with RXRalpha in monkey CV1 cells assessed as PPRE transcriptional activation incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandPNGBDBM50373907(CHEMBL271394)
Affinity DataEC50:  30nMAssay Description:Agonist activity at mouse PPARalpha expressed in CV1 cells by transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50225835((2s,5s)-2-methyl-5-(4-(5-methyl-2-p-tolyloxazol-4-...)
Affinity DataEC50:  30nMAssay Description:Agonist activity at mouse PPARalpha expressed in CV1 cells by transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50081225(2-(4-{2-[3-(4-Fluoro-phenyl)-1-heptyl-ureido]-ethy...)
Affinity DataEC50:  33nMAssay Description:Compound was tested for its agonist activity against murine Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor transfected CV-1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM24566(JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...)
Affinity DataEC50:  40nMAssay Description:Effective concentration against murine PPARalpha in transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM24566(JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...)
Affinity DataEC50:  40nMAssay Description:The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase activity w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50293847((2R)-2-{3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(triflu...)
Affinity DataEC50:  40nMAssay Description:Agonist activity at mouse PPARalpha receptor expressed in african green monkey COS1 cells co-transfected with fused yeast Gal4-DBD by transactivation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
LigandPNGBDBM28699(2-(4-chlorophenoxy)-2-methylpropanoic acid | CHEMB...)
Affinity DataEC50:  42nMAssay Description:Effective concentration against murine PPARalpha in transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50081224(2-(4-{2-[1-(5-Cyclohexyl-pentyl)-3-(4-fluoro-pheny...)
Affinity DataEC50:  53nMAssay Description:Compound was tested for its agonist activity against murine Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor transfected CV-1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50229208(N-(4-(2,2,2-trifluoroethylsulfonamido)benzyl)-4-me...)
Affinity DataEC50:  60nMAssay Description:Agonist activity at mouse PPARalpha assessed as receptor activation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
LigandPNGBDBM50229207(N-(4-(trifluoromethylsulfonamido)benzyl)-4-(4-meth...)
Affinity DataEC50:  80nMAssay Description:Agonist activity at mouse PPARalpha assessed as receptor activation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
LigandPNGBDBM50030474(US9562012, rosiglitazone | CHEBI:50122 | Avandamet...)
Affinity DataIC50: 80nMAssay Description:Activation of mouse liver PPARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
LigandPNGBDBM50156523(3-{4-[2-(2-Biphenyl-3-yl-5-methyl-oxazol-4-yl)-eth...)
Affinity DataEC50:  91nMAssay Description:Transactivation activity for mouse Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
LigandPNGBDBM50373910(CHEMBL410704)
Affinity DataEC50:  100nMAssay Description:Agonist activity at mouse PPARalpha expressed in CV1 cells by transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
LigandPNGBDBM24566(JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...)
Affinity DataKi:  100nMAssay Description:Binding affinity towards peroxisome proliferator activated receptor alpha (murinePPAR alpha)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50373024(CHEMBL447533)
Affinity DataEC50:  100nMAssay Description:Agonist activity at mouse PPARalpha by transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50293849((2R)-2-{3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(triflu...)
Affinity DataEC50:  110nMAssay Description:Agonist activity at mouse PPARalpha receptor expressed in african green monkey COS1 cells co-transfected with fused yeast Gal4-DBD by transactivation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
LigandPNGBDBM50293851((2R)-2-{3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(triflu...)
Affinity DataEC50:  120nMAssay Description:Agonist activity at mouse PPARalpha receptor expressed in african green monkey COS1 cells co-transfected with fused yeast Gal4-DBD by transactivation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
LigandPNGBDBM50081222(2-(4-{2-[1-Cycloheptyl-3-(2,4-difluoro-phenyl)-ure...)
Affinity DataEC50:  120nMAssay Description:Compound was tested for its agonist activity against murine Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor transfected CV-1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50229210(N-(4-(trifluoromethylsulfonamido)benzyl)-5-methoxy...)
Affinity DataEC50:  130nMAssay Description:Agonist activity at mouse PPARalpha assessed as receptor activation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
LigandPNGBDBM28802(2-{[(5-{[2-(4-chlorophenyl)-5-methyl-1,3-oxazol-4-...)
Affinity DataEC50:  144nMAssay Description:Agonist activity at mouse PPAR-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2017
Entry Details Article
PubMed
LigandPNGBDBM28802(2-{[(5-{[2-(4-chlorophenyl)-5-methyl-1,3-oxazol-4-...)
Affinity DataEC50:  145nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2009
Entry Details Article
PubMed
LigandPNGBDBM50156523(3-{4-[2-(2-Biphenyl-3-yl-5-methyl-oxazol-4-yl)-eth...)
Affinity DataIC50: 146nMAssay Description:In vitro inhibition of mouse Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
LigandPNGBDBM50293844(1-{3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(trifluorome...)
Affinity DataEC50:  150nMAssay Description:Agonist activity at mouse PPARalpha receptor expressed in african green monkey COS1 cells co-transfected with fused yeast Gal4-DBD by transactivation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
LigandPNGBDBM50156524(3-{4-[2-(2-Biphenyl-3-yl-5-methyl-oxazol-4-yl)-eth...)
Affinity DataEC50:  151nMAssay Description:Transactivation activity for mouse Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
LigandPNGBDBM50448033(CHEMBL3115237)
Affinity DataEC50:  170nMAssay Description:Agonist activity at mouse PPARalpha expressed in CV-1 cells by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
LigandPNGBDBM50145723(3-{4-[2-(2-Biphenyl-3-yl-5-methyl-oxazol-4-yl)-eth...)
Affinity DataEC50:  173nMAssay Description:Transactivation activity for mouse Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
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