Compile Data Set for Download or QSAR
Report error Found 3526 of affinity data for UniProtKB/TrEMBL: P25103
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50140783(2-Hydroxymethyl-4-phenyl-quinoline-3-carboxylic ac...)
Affinity DataIC50: 0.000100nMAssay Description:Binding affinity against human Tachykinin receptor 1 expressed in astrocytoma UC11MG cells using [125I]- SP radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50295070((S)-1-((2S,5S,11R,14S)-14-amino-5-benzyl-15-(4-hyd...)
Affinity DataKi:  0.00110nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50295070((S)-1-((2S,5S,11R,14S)-14-amino-5-benzyl-15-(4-hyd...)
Affinity DataKi:  0.00110nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50140770(2-Aminomethyl-4-phenyl-quinoline-3-carboxylic acid...)
Affinity DataIC50: 0.00170nMAssay Description:Binding affinity against human Tachykinin receptor 1 expressed in astrocytoma UC11MG cells using [125I]- SP radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50295069((S)-1-((2S,5S,11R,14S)-14-amino-5-benzyl-2-butyl-1...)
Affinity DataKi:  0.00280nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50295069((S)-1-((2S,5S,11R,14S)-14-amino-5-benzyl-2-butyl-1...)
Affinity DataKi:  0.00280nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50498577(CHEMBL3609619)
Affinity DataKi:  0.00400nMAssay Description:Displacement of [3H]-substance P from human NK1 receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50498575(CHEMBL3608939)
Affinity DataKi:  0.00400nMAssay Description:Displacement of [3H]-substance P from human NK1 receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM86055(SSR240600)
Affinity DataKi:  0.00430nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50323869((S)-1-((4S,7S,13R)-13-((S)-2-amino-3-(4-hydroxyphe...)
Affinity DataKi:  0.00530nMAssay Description:Displacement of [3H]substance P frome human NK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50323869((S)-1-((4S,7S,13R)-13-((S)-2-amino-3-(4-hydroxyphe...)
Affinity DataKi:  0.00530nMAssay Description:Displacement of [3H]substance P frome human NK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50439327(CHEMBL2419544)
Affinity DataKi:  0.00570nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM86055(SSR240600)
Affinity DataKi:  0.00610nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50264406(Tyr-D-Ala-Gly-Phe-Met-Pro-Leu-Trp-NH-3,5-Bzl(CF 3)...)
Affinity DataKi:  0.00650nMAssay Description:Displacement of [3H]substance P frome human NK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50264406(Tyr-D-Ala-Gly-Phe-Met-Pro-Leu-Trp-NH-3,5-Bzl(CF 3)...)
Affinity DataKi:  0.00650nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50264406(Tyr-D-Ala-Gly-Phe-Met-Pro-Leu-Trp-NH-3,5-Bzl(CF 3)...)
Affinity DataKi:  0.00700nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50264406(Tyr-D-Ala-Gly-Phe-Met-Pro-Leu-Trp-NH-3,5-Bzl(CF 3)...)
Affinity DataKi:  0.00700nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50341318((S)-1-((2S,5S,11R,14S)-14-amino-5-benzyl-15-(4-hyd...)
Affinity DataKi:  0.00790nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50341318((S)-1-((2S,5S,11R,14S)-14-amino-5-benzyl-15-(4-hyd...)
Affinity DataKi:  0.00790nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50439329(CHEMBL2419542)
Affinity DataKi:  0.00900nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50140773(2-Bromomethyl-4-phenyl-quinoline-3-carboxylic acid...)
Affinity DataIC50: 0.0100nMAssay Description:Binding affinity against human Tachykinin receptor 1 expressed in astrocytoma UC11MG cells using [125I]- SP radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50140785(2-Methylaminomethyl-4-phenyl-quinoline-3-carboxyli...)
Affinity DataIC50: 0.0110nMAssay Description:Binding affinity against human Tachykinin receptor 1 expressed in astrocytoma UC11MG cells using [125I]- SP radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50067935((2S,3S)-N-(2-methoxy-5-(trifluoromethoxy)benzyl)-2...)
Affinity DataIC50: 0.0120nMAssay Description:Displacement of [125I]BH-SP from NK1 receptor in human IM9 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50264406(Tyr-D-Ala-Gly-Phe-Met-Pro-Leu-Trp-NH-3,5-Bzl(CF 3)...)
Affinity DataIC50: 0.0126nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50264406(Tyr-D-Ala-Gly-Phe-Met-Pro-Leu-Trp-NH-3,5-Bzl(CF 3)...)
Affinity DataIC50: 0.0126nMAssay Description:Displacement of [3H]substance P frome human NK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50314371((1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)e...)
Affinity DataIC50: 0.0130nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50498573(CHEMBL3609620)
Affinity DataKi:  0.0160nMAssay Description:Displacement of [3H]-substance P from human NK1 receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50364189(CHEMBL1951813)
Affinity DataIC50: 0.0170nMAssay Description:Displacement of [125I]BH-SP from tachykinin NK1 receptor in human IM9 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50364190(CHEMBL1951810)
Affinity DataIC50: 0.0200nMAssay Description:Displacement of [125I]BH-SP from tachykinin NK1 receptor in human IM9 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50364190(CHEMBL1951810)
Affinity DataIC50: 0.0200nMAssay Description:Displacement of [125I]BH-SP from tachykinin NK1 receptor in human IM9 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50186527((R)-3-((1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)m...)
Affinity DataKi:  0.0200nMAssay Description:Displacement of [3H]Sar-Met substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50357169(CHEMBL1917866)
Affinity DataIC50: 0.0250nMAssay Description:Displacement of [125I]BH-SP from NK1 receptor in human IM9 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50419354(GR205171A | VOFOPITANT DIHYDROCHLORIDE)
Affinity DataKi:  0.0251nMAssay Description:Displacement of [125I]BH-SP from NK1 receptor in human IM9 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50408664(GR-205171 | VOFOPITANT)
Affinity DataKi:  0.0251nMAssay Description:Inhibition of [3H]-substance P binding to human NK1 receptor expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2018
Entry Details

TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM47085(US8592454, 71b)
Affinity DataIC50: 0.0270nMAssay Description:Radioligand receptor binding inhibitory assay using human NK receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2014
Entry Details
US Patent

TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM106978(US8592454, 176)
Affinity DataIC50: 0.0290nMAssay Description:Radioligand receptor binding inhibitory assay using human NK receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2014
Entry Details
US Patent

TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50220124(1-(4-((3S,4R)-3-(5-(2-(3,5-bis(trifluoromethyl)phe...)
Affinity DataIC50: 0.0300nMAssay Description:Displacement of [125I]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM106983(US8592454, 420)
Affinity DataIC50: 0.0300nMAssay Description:Radioligand receptor binding inhibitory assay using human NK receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2014
Entry Details
US Patent

TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50498569(CHEMBL3609617)
Affinity DataKi:  0.0300nMAssay Description:Displacement of [3H]-substance P from human NK1 receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50140786(4-Phenyl-quinoline-3-carboxylic acid (3,5-bis-trif...)
Affinity DataIC50: 0.0300nMAssay Description:Binding affinity against human Tachykinin receptor 1 expressed in astrocytoma UC11MG cells using [125I]- SP radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50413891(VESTIPITANT)
Affinity DataKd:  0.0302nMAssay Description:Binding affinity to human recombinant NK1 receptor expressed in CHO cells assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM106974(US8592454, 25)
Affinity DataIC50: 0.0310nMAssay Description:Radioligand receptor binding inhibitory assay using human NK receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2014
Entry Details
US Patent

TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50470670(CHEMBL149557)
Affinity DataKi:  0.0316nMAssay Description:Binding affinity to Tachykinin receptor 1 stably expressed in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50364202(CHEMBL1951626)
Affinity DataIC50: 0.0320nMAssay Description:Displacement of [125I]BH-SP from tachykinin NK1 receptor in human IM9 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM106979(US8592454, 192)
Affinity DataIC50: 0.0320nMAssay Description:Radioligand receptor binding inhibitory assay using human NK receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2014
Entry Details
US Patent

TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50439326(CHEMBL2419537)
Affinity DataKi:  0.0340nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50364195(CHEMBL1951633)
Affinity DataIC50: 0.0350nMAssay Description:Displacement of [125I]BH-SP from tachykinin NK1 receptor in human IM9 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50357186(CHEMBL1917853)
Affinity DataIC50: 0.0390nMAssay Description:Displacement of [125I]BH-SP from NK1 receptor in human IM9 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM106982(US8592454, 378)
Affinity DataIC50: 0.0390nMAssay Description:Radioligand receptor binding inhibitory assay using human NK receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2014
Entry Details
US Patent

TargetSubstance-P receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50410193(GR-203040 | CHEMBL356062)
Affinity DataKi:  0.0398nMAssay Description:Inhibition of [3H]-substance P binding to human NK1 receptor expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2018
Entry Details

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