Compile Data Set for Download or QSAR
Report error Found 11 of affinity data for UniProtKB/TrEMBL: Q27783
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Trypanosoma brucei brucei)
Vyera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 585342BDBM585342(US11530198, Example 94 | 5-(4-(3-(2-ethylpyrimidin...)
Affinity DataIC50: 0.891nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2023
Entry Details
US Patent

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Trypanosoma brucei brucei)
Vyera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 66082BDBM66082(SMR000449324 | MLS001401431 | (2S)-2-[[4-[[2,4-bis...)
Affinity DataIC50: 1.29nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2023
Entry Details
US Patent

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Trypanosoma brucei brucei)
Vyera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50531785BDBM50531785(CHEMBL4543226 | US11530198, Example 69)
Affinity DataIC50: 2nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2023
Entry Details
US Patent

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Trypanosoma brucei brucei)
Vyera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50531784BDBM50531784(Fanotaprim | TRC-2533 | TRC-2533-NX | VYR-006 | US...)
Affinity DataIC50: 2.09nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2023
Entry Details
US Patent

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Trypanosoma brucei brucei)
Vyera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 585326BDBM585326(US11530198, Example 100 | 5-(4-(3-(2-chloropyrimid...)
Affinity DataIC50: 2.51nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2023
Entry Details
US Patent

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Trypanosoma brucei brucei)
Vyera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50531797BDBM50531797(CHEMBL4550110 | US11530198, Example 86)
Affinity DataIC50: 2.51nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2023
Entry Details
US Patent

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Trypanosoma brucei brucei)
Vyera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 585317BDBM585317(US11530198, Example 95 | 5-(4-(3-(2-ethylpyrimidin...)
Affinity DataIC50: 3.80nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2023
Entry Details
US Patent

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Trypanosoma brucei brucei)
Vyera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50531786BDBM50531786(CHEMBL4573445 | US11530198, Example 74)
Affinity DataIC50: 5.62nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2023
Entry Details
US Patent

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Trypanosoma brucei brucei)
Vyera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50531783BDBM50531783(CHEMBL4591892 | US11530198, Example 87)
Affinity DataIC50: 7.41nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2023
Entry Details
US Patent

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Trypanosoma brucei brucei)
Vyera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50531779BDBM50531779(CHEMBL4553229 | US11530198, Example 4)
Affinity DataIC50: 31.6nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2023
Entry Details
US Patent

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Trypanosoma brucei brucei)
Vyera Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 18512BDBM18512(cid_4993 | CHEMBL36 | 5-(4-chlorophenyl)-6-ethylpy...)
Affinity DataIC50: 407nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2023
Entry Details
US Patent