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Report error Found 262 for UniProtKB: Q99895
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50101132(1,3-Dibenzyl-[1,3]diazetidine-2,4-dione | CHEMBL47...)
Affinity DataIC50: 0.690nMAssay Description:Compound was evaluated for its inhibitory activity against bovine pancreatic alpha-chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50101131(1,3-Di-p-tolyl-[1,3]diazetidine-2,4-dione | CHEMBL...)
Affinity DataIC50: 2.40nMAssay Description:Compound was evaluated for its inhibitory activity against bovine pancreatic alpha-chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50072290((3S,3aR,6aS)-3-Allyl-hexahydro-cyclopenta[b]furan-...)
Affinity DataIC50: 7nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM87059(CHEMBL247767 | Chymostatin)
Affinity DataKi:  9.36nMAssay Description:inhibitory activity against alpha chymotrypsin from bovine pancreas.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM87059(CHEMBL247767 | Chymostatin)
Affinity DataKi:  9.36nMAssay Description:In vitro inhibitory activity was determined against bovine pancreas chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50098882(4-[2-(5-Amino-6-oxo-2-m-tolyl-6H-pyrimidin-1-yl)-a...)
Affinity DataKi:  12.6nMAssay Description:In vitro inhibitory activity was determined against bovine pancreas chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM23705(4-bromo-1-[(4-methylphenyl)carbonyl]-1H-pyrazole |...)
Affinity DataIC50: 15nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM23700(methyl 1-[(4-chlorophenyl)carbonyl]-1H-pyrazole-5-...)
Affinity DataIC50: 15nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50068918((S)-4-((2S,3S)-2-Benzyloxycarbonylamino-3-methyl-p...)
Affinity DataKi:  34nMAssay Description:Compound was evaluated for inhibitory activity against Bovine ChymotrypsinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50072282((3R,3aR,6aS)-3-Allyl-hexahydro-cyclopenta[b]furan-...)
Affinity DataIC50: 37nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM23698(4-chloro-1-[(4-fluorophenyl)carbonyl]-1H-pyrazole ...)
Affinity DataIC50: 40nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM23709(3-methyl-1-[(3,4,5-trimethoxyphenyl)carbonyl]-1H-p...)
Affinity DataIC50: 50nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50120284(Peptide Boronic Acid analogue | CHEMBL107656)
Affinity DataIC50: 50nMAssay Description:Inhibitory concentration against Human pancreatic Serine protease chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50036127({2-Oxo-6-phenyl-1-[(3,3,3-trifluoro-1-isopropyl-2-...)
Affinity DataKi:  55nMAssay Description:Tested for inhibitory activity against bovine pancreatic chymotrypsinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50036127({2-Oxo-6-phenyl-1-[(3,3,3-trifluoro-1-isopropyl-2-...)
Affinity DataKi:  55nMAssay Description:The compound was evaluated for the binding affinity against bovine pancreatic chymotrypsinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM23704(1-benzoyl-N-phenyl-1H-pyrazole-3-carboxamide | N-B...)
Affinity DataIC50: 57nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50120311(Peptide Boronic Acid analogue | CHEMBL320814)
Affinity DataIC50: 65nMAssay Description:Inhibitory concentration against Human pancreatic Serine protease chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50072284((1S,2R,4aR,6aS,6bS,7R,9aS,10aS)-2-Acetoxy-1,4a,6a,...)
Affinity DataIC50: 70nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50120309(Peptide Boronic Acid analogue | CHEMBL108189)
Affinity DataIC50: 70nMAssay Description:Inhibitory concentration against Human pancreatic Serine protease chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50120298(Peptide Boronic Acid analogue | CHEMBL109434)
Affinity DataIC50: 75nMAssay Description:Inhibitory concentration against Human pancreatic Serine protease chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50072289((3S,3aR,6aS)-3-(4-Methyl-2-oxo-pent-3-enyl)-hexahy...)
Affinity DataIC50: 100nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50072292((3S,3aS,6aS)-3-Phenylsulfanyl-hexahydro-cyclopenta...)
Affinity DataIC50: 100nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM113297(US9695194, 14)
Affinity DataKi: <100nM ΔG°: <-41.6kJ/molepH: 7.2 T: 2°CAssay Description:Materials: Chymotrypsin, bovine, 25 ug (Roche, sequence grade), Substrate S-2586 (Chromogenics, cat. no. 82 08 94). Chymotrypsin activity was determi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM113248(US9695194, 7)
Affinity DataKi: <100nM ΔG°: <-41.6kJ/molepH: 7.2 T: 2°CAssay Description:Materials: Chymotrypsin, bovine, 25 ug (Roche, sequence grade), Substrate S-2586 (Chromogenics, cat. no. 82 08 94). Chymotrypsin activity was determi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM113300(US9695194, 16)
Affinity DataKi: <100nM ΔG°: <-41.6kJ/molepH: 7.2 T: 2°CAssay Description:Materials: Chymotrypsin, bovine, 25 ug (Roche, sequence grade), Substrate S-2586 (Chromogenics, cat. no. 82 08 94). Chymotrypsin activity was determi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50072286((3R,3aR,6aS)-3-Benzyl-hexahydro-cyclopenta[b]furan...)
Affinity DataIC50: 100nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50072285((3R,3aS,6aS)-3-Phenylsulfanyl-hexahydro-cyclopenta...)
Affinity DataIC50: 100nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM113296(US9695194, 13)
Affinity DataKi: <100nM ΔG°: <-41.6kJ/molepH: 7.2 T: 2°CAssay Description:Materials: Chymotrypsin, bovine, 25 ug (Roche, sequence grade), Substrate S-2586 (Chromogenics, cat. no. 82 08 94). Chymotrypsin activity was determi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM113119(US9695194, 6)
Affinity DataKi: <100nM ΔG°: <-41.6kJ/molepH: 7.2 T: 2°CAssay Description:Materials: Chymotrypsin, bovine, 25 ug (Roche, sequence grade), Substrate S-2586 (Chromogenics, cat. no. 82 08 94). Chymotrypsin activity was determi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50072283((3S,3aR,6aS)-3-Benzyl-hexahydro-cyclopenta[b]furan...)
Affinity DataIC50: 100nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM113299(US9695194, 15)
Affinity DataKi: <100nM ΔG°: <-41.6kJ/molepH: 7.2 T: 2°CAssay Description:Materials: Chymotrypsin, bovine, 25 ug (Roche, sequence grade), Substrate S-2586 (Chromogenics, cat. no. 82 08 94). Chymotrypsin activity was determi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM113283(US9695194, 8)
Affinity DataKi: <100nM ΔG°: <-41.6kJ/molepH: 7.2 T: 2°CAssay Description:Materials: Chymotrypsin, bovine, 25 ug (Roche, sequence grade), Substrate S-2586 (Chromogenics, cat. no. 82 08 94). Chymotrypsin activity was determi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50098877(4-{2-[5-Amino-2-(3-methoxy-phenyl)-6-oxo-6H-pyrimi...)
Affinity DataKi:  109nMAssay Description:In vitro inhibitory activity was determined against bovine pancreas chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM23702(3-[(2,4-dimethylphenyl)carbonyl]-1-[(4-fluoropheny...)
Affinity DataIC50: 120nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM23706(1-[(3,4-dichlorophenyl)carbonyl]-1H-pyrazole | N-B...)
Affinity DataIC50: 125nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50098870({4-[2-(5-Amino-6-oxo-2-m-tolyl-6H-pyrimidin-1-yl)-...)
Affinity DataKi:  147nMAssay Description:In vitro inhibitory activity was determined against bovine pancreas chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50061024((2-Methyl-1-{(S)-oxo-[(S)-2-((S)-3,3,3-trifluoro-1...)
Affinity DataKi:  149nMAssay Description:Binding affinity for human pancreatic ChymotrypsinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50093722((6R,7R)-3-(4-Carboxymethyl-4H-[1,2,4]triazol-3-yls...)
Affinity DataIC50: 160nMAssay Description:The compound was evaluated for the inhibitory activity against alpha-chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50098884(4-[2-(5-Amino-6-oxo-2-pyridin-3-yl-6H-pyrimidin-1-...)
Affinity DataKi:  171nMAssay Description:In vitro inhibitory activity was determined against bovine pancreas chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50098886(4-[2-(5-Amino-6-oxo-2-phenyl-6H-pyrimidin-1-yl)-ac...)
Affinity DataKi:  177nMAssay Description:In vitro inhibitory activity was determined against bovine pancreas chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM23710(1-[(4-methylphenyl)carbonyl]-3-nitro-1H-pyrazole |...)
Affinity DataIC50: 190nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM113293(US9695194, 10)
Affinity DataKi:  200nM ΔG°:  -39.8kJ/molepH: 7.2 T: 2°CAssay Description:Materials: Chymotrypsin, bovine, 25 ug (Roche, sequence grade), Substrate S-2586 (Chromogenics, cat. no. 82 08 94). Chymotrypsin activity was determi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50098885(4-[2-(5-Amino-6-oxo-2-pyridin-4-yl-6H-pyrimidin-1-...)
Affinity DataKi:  240nMAssay Description:In vitro inhibitory activity was determined against bovine pancreas chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM23712(1-[(2-methylphenyl)carbonyl]-4-nitro-1H-pyrazole |...)
Affinity DataIC50: 240nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50025549(6-Chloro-3-phenyl-pyran-2-one | CHEMBL274455)
Affinity DataKi:  270nMAssay Description:In vitro binding affinity towards alpha-chymotrypsin from bovine pancreas.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50120286(Peptide Boronic Acid analogue | CHEMBL322933)
Affinity DataIC50: 280nMAssay Description:Inhibitory concentration against Human pancreatic Serine protease chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50098866(4-({4-[2-(5-Amino-6-oxo-2-m-tolyl-6H-pyrimidin-1-y...)
Affinity DataKi:  282nMAssay Description:In vitro inhibitory activity was determined against bovine pancreas chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50098883(4-[2-(5-Amino-6-oxo-2-m-tolyl-6H-pyrimidin-1-yl)-a...)
Affinity DataKi:  295nMAssay Description:In vitro inhibitory activity was determined against bovine pancreas chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50120292(Peptide Boronic Acid analogue | CHEMBL322110)
Affinity DataIC50: 300nMAssay Description:Inhibitory concentration against Human pancreatic Serine protease chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50096724((S)-4-((S)-1-{(S)-1-[(S)-1-((R)-1-Aminooxalyl-pent...)
Affinity DataIC50: 300nMAssay Description:Compound was tested for inhibition of Serine protease chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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