45 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
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Article Title
Organization
Ionic derivatives of betulinic acid exhibit antiviral activity against herpes simplex virus type-2 (HSV-2), but not HIV-1 reverse transcriptase.
Mercer University
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
Glaxosmithkline
A Selective, Cell-Permeable Nonphosphorylated Bicyclic Peptidyl Inhibitor against Peptidyl-Prolyl Isomerase Pin1.
The Ohio State University
Structure-guided design of a series of MCL-1 inhibitors with high affinity and selectivity.
Abbvie
Synthesis of linear and cyclic guazatine derivatives endowed with antibacterial activity.
University of Siena
Synthesis and preliminary evaluation in tumor bearing mice of new (18)F-labeled arylsulfone matrix metalloproteinase inhibitors as tracers for positron emission tomography.
Universit£
Inhibition of protein glycation by urea and thiourea derivatives of glycine/proline conjugated benzisoxazole analogue - synthesis and structure-activity studies.
University of Mysore
New approach to measure protein binding based on a parallel artificial membrane assay and human serum albumin.
Universitat De Barcelona
Bicyclization and tethering to albumin yields long-acting peptide antagonists.
Ecole Polytechnique F�D�Rale De Lausanne
Use of a surface plasmon resonance method to investigate antibiotic and plasma protein interactions.
Cnrs-Cpbs/Umr 5236
Probing lipid- and drug-binding domains with fluorescent dyes.
European Molecular Biology Laboratory
Synthesis and antiglycation potentials of bergenin derivatives.
India Institute of Chemical Technology
Identification, characterization, and implications of species-dependent plasma protein binding for the oral Hedgehog pathway inhibitor vismodegib (GDC-0449).
Genentech
Synthesis and characterization of novel 1,2,4-triazine derivatives with antiproliferative activity.
Martin-Luther-Universit£T Halle-Wittenberg
In vivo targeting of tumor-associated carbonic anhydrases using acetazolamide derivatives.
Institute of Pharmaceutical Sciences
Design, synthesis and spectroscopic studies of resveratrol aliphatic acid ligands of human serum albumin.
East Tennessee State University
Biphenyls as potent vitronectin receptor antagonists. Part 3: Squaric acid amides.
Bayer Healthcare
Correlation of carboxylic acid pKa to protein binding and antibacterial activity of a novel class of bacterial translation inhibitors.
Pharmacia
Human serum albumin binding assay based on displacement of a non selective fluorescent inhibitor.
Pharmacia
Preparation of novel anthranilic acids as antibacterial agents: extensive evaluation of structural and physical properties on antibacterial activity and human serum albumin affinity.
Pharmacia
Discovery and structure-activity relationship of antagonists of B-cell lymphoma 2 family proteins with chemopotentiation activity in vitro and in vivo.
Abbott Laboratories
Identification and Validation of New Interleukin-2 Ligands Using DNA-Encoded Libraries.
Philochem
MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 2: achieving activity in vivo through the use of alternative scaffolds.
Daiichi Pharmaceutical
Using porphyrins as albumin-binding molecules to enhance antitumor efficacies and reduce systemic toxicities of antimicrobial peptides.
Fuzhou University
N-[(2-Sulfo)-9-fluorenylmethoxycarbonyl](3)-gentamicin C(1) is a long-acting prodrug derivative.
Institute of Science
Halogenated diazirines as photolabel mimics of the inhaled haloalkane anesthetics.
University of Pennsylvania Health System
The Medicinal Chemistry in the Era of Machines and Automation: Recent Advances in Continuous Flow Technology.
University of Perugia
Mechanisms of Specific versus Nonspecific Interactions of Aggregation-Prone Inhibitors and Attenuators.
University Health Network
Ligand-Based Fluorine NMR Screening: Principles and Applications in Drug Discovery Projects.
Lavis
A Potent Isoprenylcysteine Carboxylmethyltransferase (ICMT) Inhibitor Improves Survival in Ras-Driven Acute Myeloid Leukemia.
Universidad Complutense De Madrid
Multitarget CFTR Modulators Endowed with Multiple Beneficial Side Effects for Cystic Fibrosis Patients: Toward a Simplified Therapeutic Approach ?.
Universit£
Discovery of a benzothiophene-flavonol halting miltefosine and antimonial drug resistance in Leishmania parasites through the application of medicinal chemistry, screening and genomics.
University of Modena and Reggio Emilia
Alkyl-guanidine Compounds as Potent Broad-Spectrum Antibacterial Agents: Chemical Library Extension and Biological Characterization.
University of Siena
Synthesis and anti-HIV activity of 1,1'-dideoxygossypol and related compounds.
University of New Mexico School of Medicine
Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach.
Molecular Discovery
Enthalpy-Driven Stabilization of Transthyretin by AG10 Mimics a Naturally Occurring Genetic Variant That Protects from Transthyretin Amyloidosis.
University of The Pacific
Phylogenomics of 2,4-Diacetylphloroglucinol-Producing Pseudomonas and Novel Antiglycation Endophytes from Piper auritum.
Unidad De Gen�Mica Avanzada (Langebio)
Antidiabetic potential of phytochemicals isolated from the stem bark of Myristica fatua Houtt. var. magnifica (Bedd.) Sinclair.
Csir-National Institute For Interdisciplinary Science and Technology
High-content screen using zebrafish (Danio rerio) embryos identifies a novel kinase activator and inhibitor.
West Virginia University
Oligo-aspartic acid conjugates with benzo[c][2,6]naphthyridine-8-carboxylic acid scaffold as picomolar inhibitors of CK2.
University of Tartu