PMID

Data

Article Title

Organization

10-iodo-11H-indolo[3,2-c]quinoline-6-carboxylic acids are selective inhibitors of DYRK1A.

Technische Universit£T Braunschweig

Acridone alkaloids from Glycosmis chlorosperma as DYRK1A inhibitors.

Institut De Chimie Des Substances Naturelles

9- and 11-substituted 4-azapaullones are potent and selective inhibitors of African trypanosoma.

Technische Universit£T Braunschweig

Chemical synthesis and biological validation of immobilized protein kinase inhibitory Leucettines.

Universit£

Small-molecule pyrimidine inhibitors of the cdc2-like (Clk) and dual specificity tyrosine phosphorylation-regulated (Dyrk) kinases: development of chemical probe ML315.

University of Kansas Specialized Chemistry Center

Synthesis and biological evaluation of selective and potent cyclin-dependent kinase inhibitors.

TBA

Selectivity, cocrystal structures, and neuroprotective properties of leucettines, a family of protein kinase inhibitors derived from the marine sponge alkaloid leucettamine B.

Cnrs

Synthesis and biological evaluation of analogs of the marine alkaloids granulatimide and isogranulatimide.

Universit£

Synthesis, biological evaluation, and molecular modeling of natural and unnatural flavonoidal alkaloids, inhibitors of kinases.

Institut De Chimie Des Substances Naturelles (Icsn)

A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.

University of Oxford

Leucettines, a class of potent inhibitors of cdc2-like kinases and dual specificity, tyrosine phosphorylation regulated kinases derived from the marine sponge leucettamine B: modulation of alternative pre-RNA splicing.

Universite£? De Rennes 1

Synthesis and biological evaluation of Haspin inhibitors: Kinase inhibitory potency and cellular activity.

Universit£

Structure-Activity Relationship in the Leucettine Family of Kinase Inhibitors.

Manros Therapeutics & Perha Pharmaceuticals

Recent advances in the development of active hybrid molecules in the treatment of cardiovascular diseases.

Western University of Health Sciences

Development of novel conformationally restricted selective Clk1/4 inhibitors through creating an intramolecular hydrogen bond involving an imide linker.

German University In Cairo

In vitro identification of imidazo[1,2-a]pyrazine-based antileishmanial agents and evaluation of L. major casein kinase 1 inhibition.

Universit£

Discovery of simplified benzazole fragments derived from the marine benzosceptrin B as necroptosis inhibitors involving the receptor interacting protein Kinase-1.

Universit£

New pyrido[3,4-g]quinazoline derivatives as CLK1 and DYRK1A inhibitors: synthesis, biological evaluation and binding mode analysis.

Universit£

Kinase inhibitions in pyrido[4,3-h] and [3,4-g]quinazolines: Synthesis, SAR and molecular modeling studies.

Universit£

A ?-glucuronidase-responsive albumin-binding prodrug for potential selective kinase inhibitor-based cancer chemotherapy.

Universit£

Structure-based design of novel quinoxaline-2-carboxylic acids and analogues as Pim-1 inhibitors.

University of Tours

Benzofuro[3,2-d]pyrimidines inspired from cercosporamide CaPkc1 inhibitor: Synthesis and evaluation of fluconazole susceptibility restoration.

Universit£

Exploration of the imidazo[1,2-b]pyridazine scaffold as a protein kinase inhibitor.

University of Paris

N-(1H-Pyrazol-3-yl)quinazolin-4-amines as a novel class of casein kinase 1?/? inhibitors: Synthesis, biological evaluation and molecular modeling studies.

Rajiv Gandhi Proudyogiki Vishwavidyalaya