37 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Synthesis and alpha-adrenergic activities of 2- and 4-substituted imidazoline and imidazole analogues.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Ohio State University
Structure-affinity relationships of 12-sulfonyl derivatives of 5,8,8a,9,10,11,12,12a,13,13a-decahydro-6H-isoquino[2,1-g][1 ,6] naphthyridines at alpha-adrenoceptors.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Syntex Research
New 1,4-dihydropyridine derivatives combining calcium antagonism and alpha-adrenolytic properties.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Institut De Pharmacologie (Ua 589 Cnrs)
Radioiodinated p-iodoclonidine: a high-affinity probe for the alpha 2-adrenergic receptor.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
TBA
Conformationally defined adrenergic agents. 4. 1-(aminomethyl)phthalans: synthesis and pharmacological consequences of the phthalan ring oxygen atom.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
TBA
Development of an affinity ligand for purification of alpha 2-adrenoceptors from human platelet membranes.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
TBA
Synthesis and biological evaluation of 2-aryliminopyrrolidines as selective ligands for I1 imidazoline receptors: discovery of new sympatho-inhibitory hypotensive agents with potential beneficial effects in metabolic syndrome.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Universit£
a2-adrenoceptor antagonists: synthesis, pharmacological evaluation, and molecular modeling investigation of pyridinoguanidine, pyridino-2-aminoimidazoline and their derivatives.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Trinity College
Targeting dopamine D3 and serotonin 5-HT1A and 5-HT2A receptors for developing effective antipsychotics: synthesis, biological characterization, and behavioral studies.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Universit£
Selective optimization of side activities: another way for drug discovery.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Prestwick Chemical
Synthesis and pharmacological evaluation of 1-(aminomethyl)-3,4-dihydro-5-hydroxy-1H-2-benzopyrans as dopamine D1 selective ligands.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Abbott Laboratories
Syntheses and adrenergic activities of ring-fluorinated epinephrines.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
National Institute of Diabetes
N-[2-hydroxy-5-[2-(methylamino)ethyl]phenyl]methanesulfonamide. A potent agonist which releases intracellular calcium by activation of alpha 1-adrenoceptors.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
TBA
(+/-)8-Amino-5,6,7,8-tetrahydroisoquinolines as novel antinociceptive agents.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Virginia Commonwealth University
The synthesis and biological activity of some known and putative metabolites of the atypical antipsychotic agent olanzapine (LY170053)![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
TBA
The discovery of CP-96,021 and CP-96,486, balanced, combined, potent and orally active leukotriene D4 (LTD4)/platelet activating factor (PAF) receptor antagonists.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
TBA
Synthesis and structure--activity relationship in a class of indolebutylpiperazines as dual 5-HT(1A) receptor agonists and serotonin reuptake inhibitors.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Merck
1H-Pyrazolo-[3,4-c]cyclophepta[1,2-c]thiophenes: a unique structural class of dopamine D4 selective ligands.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Neurogen
Substituted conformationally restricted guanidine derivatives: Probing the ?2-adrenoceptors' binding pocket.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Trinity College
Guanidine and 2-aminoimidazoline aromatic derivatives as alpha2-adrenoceptor ligands: searching for structure-activity relationships.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
University of Dublin
Guanidine and 2-aminoimidazoline aromatic derivatives as alpha(2)-adrenoceptor antagonists, 1: toward new antidepressants with heteroatomic linkers.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
University of Dublin
Imidazoline binding sites (IBS) profile modulation: key role of the bridge in determining I1-IBS or I2-IBS selectivity within a series of 2-phenoxymethylimidazoline analogues.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Universit£
Medetomidine analogs as alpha 2-adrenergic ligands. 2. Design, synthesis, and biological activity of conformationally restricted naphthalene derivatives of medetomidine.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Ohio State University
Evolution of a novel series of [(N,N-dimethylamino)propyl]- and piperazinylbenzanilides as the first selective 5-HT1D antagonists.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Glaxo Research and Development
Thiophene/thiazole-benzene replacement on guanidine derivatives targeting?![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Trinity College
Novel 2(3H)-benzothiazolones as highly potent and selective sigma-1 receptor ligands![BDB](/images/logo_bindingdb.png)
![BDB](/images/logo_bindingdb.png)
Universite De Lille