BDBM26474 5-({4-[(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl}amino)-2-methylbenzene-1-sulfonamide::GW-786034::JMC514632 Compound 13::Pazopanib::cid_10113978
SMILES CN(c1ccc2c(C)n(C)nc2c1)c1ccnc(Nc2ccc(C)c(c2)S(N)(=O)=O)n1
InChI Key InChIKey=CUIHSIWYWATEQL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 26474
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Shandong University
Curated by ChEMBL
Shandong University
Curated by ChEMBL
Affinity DataIC50: 118nMAssay Description:Inhibition of C-kit (unknown origin) after 40 mins by kinase-Glo assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Shandong University
Curated by ChEMBL
Shandong University
Curated by ChEMBL
Affinity DataIC50: 98nMAssay Description:Inhibition of VEGFR-1 (unknown origin) after 40 mins by kinase-Glo assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Shandong University
Curated by ChEMBL
Shandong University
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of VEGFR-2 (unknown origin) after 40 mins by kinase-Glo assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Shandong University
Curated by ChEMBL
Shandong University
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of VEGFR-3 (unknown origin) after 40 mins by kinase-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 163nMAssay Description:Inhibition of FGFR1 (unknown origin) after 40 mins by kinase-Glo assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Shandong University
Curated by ChEMBL
Shandong University
Curated by ChEMBL
Affinity DataIC50: 83nMAssay Description:Inhibition of PDGFRbeta (unknown origin) after 40 mins by kinase-Glo assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Shandong University
Curated by ChEMBL
Shandong University
Curated by ChEMBL
Affinity DataIC50: 274nMAssay Description:Inhibition of C-fms (unknown origin) after 40 mins by kinase-Glo assayMore data for this Ligand-Target Pair