BDBM29094 (+/-)-SLV319::(S)-3-(4-chlorophenyl)-N-(4-chlorophenylsulfonyl)-N'-methyl-4-phenyl-4,5-dihydropyrazole-1-carboxamidine::3-(4-chlorophenyl)-N''''-(4-chlorophenylsulfonyl)-N-methyl-4-phenyl-4,5-dihydro-1H-pyrazole-1-carboximidamide::4-Chloro-N-[1-[3-(4-chloro-phenyl)-4-phenyl-4,5-dihydro-pyrazol-1-yl]-1-methylamino-meth-(E)-ylidene]-benzenesulfonamide::CHEMBL158784::SLV-319::ibipinabant

SMILES CN=C(NS(=O)(=O)c1ccc(Cl)cc1)N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1

InChI Key InChIKey=AXJQVVLKUYCICH-UHFFFAOYSA-N

Data  14 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 29094   

TargetCannabinoid receptor 1(Human)
Acadia Pharmaceuticals

LigandPNGBDBM29094((+/-)-SLV319 | (S)-3-(4-chlorophenyl)-N-(4-chlorop...)
Affinity DataKi:  3nM ΔG°:  -11.5kcal/molepH: 7.2 T: 22°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Human)
Acadia Pharmaceuticals

LigandPNGBDBM29094((+/-)-SLV319 | (S)-3-(4-chlorophenyl)-N-(4-chlorop...)
Affinity DataKi:  4.10nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGTP-binding nuclear protein GSP1/CNR1(Baker's yeast)
Cns Biological Research

Curated by PDSP Ki Database
LigandPNGBDBM29094((+/-)-SLV319 | (S)-3-(4-chlorophenyl)-N-(4-chlorop...)
Affinity DataKi:  7.80nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Human)
Acadia Pharmaceuticals

LigandPNGBDBM29094((+/-)-SLV319 | (S)-3-(4-chlorophenyl)-N-(4-chlorop...)
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Human)
Acadia Pharmaceuticals

LigandPNGBDBM29094((+/-)-SLV319 | (S)-3-(4-chlorophenyl)-N-(4-chlorop...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Human)
Acadia Pharmaceuticals

LigandPNGBDBM29094((+/-)-SLV319 | (S)-3-(4-chlorophenyl)-N-(4-chlorop...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Human)
Acadia Pharmaceuticals

LigandPNGBDBM29094((+/-)-SLV319 | (S)-3-(4-chlorophenyl)-N-(4-chlorop...)
Affinity DataKi:  25nMAssay Description:Displacement of CP-55,940 binding from recombinant human cannabinoid receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Human)
Acadia Pharmaceuticals

LigandPNGBDBM29094((+/-)-SLV319 | (S)-3-(4-chlorophenyl)-N-(4-chlorop...)
Affinity DataKi:  25.2nMAssay Description:Displacement of [3H]CP-55940 from human cannabinoid CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Human)
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM29094((+/-)-SLV319 | (S)-3-(4-chlorophenyl)-N-(4-chlorop...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Human)
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM29094((+/-)-SLV319 | (S)-3-(4-chlorophenyl)-N-(4-chlorop...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Human)
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM29094((+/-)-SLV319 | (S)-3-(4-chlorophenyl)-N-(4-chlorop...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]CP-55940 from human cannabinoid CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Human)
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM29094((+/-)-SLV319 | (S)-3-(4-chlorophenyl)-N-(4-chlorop...)
Affinity DataKi: >1.00E+3nMAssay Description:Affinity to displace CP-55,940 binding from Cannabinoid receptor 2 of human expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Human)
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM29094((+/-)-SLV319 | (S)-3-(4-chlorophenyl)-N-(4-chlorop...)
Affinity DataKi:  2.00E+3nM ΔG°:  -7.69kcal/molepH: 7.2 T: 22°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGTP-binding nuclear protein GSP2/CNR2(Baker's yeast)
Cns Biological Research

Curated by PDSP Ki Database
LigandPNGBDBM29094((+/-)-SLV319 | (S)-3-(4-chlorophenyl)-N-(4-chlorop...)
Affinity DataKi:  7.94E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Human)
Acadia Pharmaceuticals

LigandPNGBDBM29094((+/-)-SLV319 | (S)-3-(4-chlorophenyl)-N-(4-chlorop...)
Affinity DataIC50:  139nMAssay Description:Inverse agonist activity against CB1 receptor expressed in human CHO cells assessed as effect on forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Human)
Acadia Pharmaceuticals

LigandPNGBDBM29094((+/-)-SLV319 | (S)-3-(4-chlorophenyl)-N-(4-chlorop...)
Affinity DataIC50:  1.91nMAssay Description:Antagonist activity against human recombinant cannabinoid-1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Human)
Acadia Pharmaceuticals

LigandPNGBDBM29094((+/-)-SLV319 | (S)-3-(4-chlorophenyl)-N-(4-chlorop...)
Affinity DataIC50:  22nMAssay Description:Displacement of 3[H]ligand from recombinant human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Human)
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM29094((+/-)-SLV319 | (S)-3-(4-chlorophenyl)-N-(4-chlorop...)
Affinity DataIC50: >5.00E+3nMAssay Description:Displacement of 3[H]ligand from recombinant human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed