BDBM10755 14C-5-hydroxy tryptamine creatinine disulfate::2-imino-1-methylimidazolidin-4-one; 3-(2-aminoethyl)-1H-indol-5-ol; bis(sulfuric acid)::5-HT::5-Hydroxy Tryptamine::5-hydroxy tryptamine creatinine disulfate::CHEMBL535832::Serotonin::[3H]-5-HT

SMILES NCCc1c[nH]c2ccc(O)cc12

InChI Key InChIKey=QZAYGJVTTNCVMB-UHFFFAOYSA-N

Data  399 KI  74 IC50  6 Kd  161 EC50

PDB links: 41 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 10755   

Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataKd:  3.16E+3nMAssay Description:Binding affinity for 5-hydroxytryptamine 2 receptor was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataKd:  13nMAssay Description:Binding affinity for 5-hydroxytryptamine 1D receptor was determinedMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataKd:  32nMAssay Description:Binding affinity for 5-hydroxytryptamine 1C receptor was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataKd:  3.20nMAssay Description:Binding affinity for 5-hydroxytryptamine 1A receptor was determinedMore data for this Ligand-Target Pair