BDBM14831 3-(3-tert-butyl-1-methyl-1H-pyrazol-5-yl)-1-(4-chlorophenyl)urea::3-(4-chlorophenyl)-1-(2-methyl-5-tert-butyl-pyrazol-3-yl)urea::CHEMBL87277::Dopamine D2 receptor and serotonin 2a receptor::diaryl urea compound 2::diaryl urea inhibitor 1
SMILES Cn1nc(cc1NC(=O)Nc1ccc(Cl)cc1)C(C)(C)C
InChI Key InChIKey=FWIJKWMXNHRSRO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 14831
Affinity DataKd: 1.16E+3nMpH: 7.0 T: 2°CAssay Description:The exchange curve assays were run as two half-reactions using an SLM Aminco Bowman Series 2 model SQ-340 fluorescence detector. In the first half re...More data for this Ligand-Target Pair
Affinity DataKd: 1.16E+3nMpH: 7.0 T: 2°CAssay Description:The exchange curve assays were run as two half-reactions using an SLM Aminco Bowman Series 2 model SQ-340 fluorescence detector. In the first half re...More data for this Ligand-Target Pair
Affinity DataKoff: 1.18E+5s-1Assay Description:Binding affinity for Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
Affinity DataKon: 0.140M-1s-1 Koff: 1.18E+5s-1Assay Description:Binding affinity for Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
Affinity DataKd: 1.19E+3nMAssay Description:Binding affinity for Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
Activity Spreadsheet -- ITC Data from BindingDB
Found 1 hit for monomerid = 14831
CellBDBM14831(3-(3-tert-butyl-1-methyl-1H-pyrazol-5-yl)-1-(4-chl...)
Boehringer Ingelheim Pharmaceuticals
Boehringer Ingelheim Pharmaceuticals
ITC DataΔH°: -5.59kcal/mole logk: 8.68E+5
pH: 7.0 T: 25.00°C
pH: 7.0 T: 25.00°C