BDBM222045 5'-O-(3''-Bromobenzoyl)-thymidine (15)

SMILES Cc1cn([C@H]2C[C@H](O)[C@@H](COC(=O)c3cccc(Br)c3)O2)c(=O)[nH]c1=O

InChI Key

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 222045   

TargetThymidine phosphorylase(Escherichia coli)
University of Karachi

LigandPNGBDBM222045(5'-O-(3''-Bromobenzoyl)-thymidine (15))
Affinity DataKi:  1.14E+4nM ΔG°:  -6.85kcal/moleT: 2°CAssay Description:In kinetic assay, the TP enzyme (0.058 U/well) was incu- bated with different concentrations of inhibitor (0.5¿0.001 mM) for 10 min at 30 C. The rea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Escherichia coli)
University of Karachi

LigandPNGBDBM222045(5'-O-(3''-Bromobenzoyl)-thymidine (15))
Affinity DataIC50:  3.33E+4nMT: 2°CAssay Description:TP inhibition assay was performed spectrophotometrically in 96-well plate. The method of Bera et al. was followed with slight modifications [Bera et ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed