BDBM237177 Arg-Cys-(D-Bip)-(D-Arg)

SMILES N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CS)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@H](CCCNC(N)=N)C(O)=O

InChI Key InChIKey=JPEJFCANQAANFI-QJEZIUSSSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 237177   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM237177(Arg-Cys-(D-Bip)-(D-Arg))
Affinity DataIC50:  750nMpH: 7.4 T: 2°CAssay Description:Recombinant human MMP-9 was expressed in Sf9 insect cells and purified by gelatin-Sepharose affinity chromatography as described previously16,17. It ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM237177(Arg-Cys-(D-Bip)-(D-Arg))
Affinity DataIC50:  2.00E+4nMpH: 7.4 T: 2°CAssay Description:TACE was purchased as an active form enzyme (R&D Systems). Hydrolysis of the TACE-substrate Mca-Pro-Leu-Ala-Gln-Ala-Val-Dpa-Arg-Ser-Ser-Ser-Arg-NH (s...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM237177(Arg-Cys-(D-Bip)-(D-Arg))
Affinity DataIC50:  1.95E+4nMpH: 7.4 T: 2°CAssay Description:The activity of recombinant human MMP-3 (catalytic domain, Calbiochem) was detected with the substrate Mca-Arg-Pro-Lys-Pro-Val-Glu-Nval-Trp-Arg-Lys(D...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM237177(Arg-Cys-(D-Bip)-(D-Arg))
Affinity DataIC50:  2.30E+3nMpH: 7.4 T: 2°CAssay Description:Recombinant human MMP-8 was purchased as an active form enzyme (Sino Biological Inc.). The enzyme activity was detected with the same fluorogenic pep...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed