BDBM237181 (D-Pyr)-(D-Cys)-Bip-Lys
SMILES C[C@@H](Nc1ccccn1)C(=O)N[C@H](CS)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(O)=O
InChI Key InChIKey=TWMVZPPZEWFNOP-NUKLZVDMSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 237181
Affinity DataIC50: 3.50E+3nMpH: 7.4 T: 2°CAssay Description:Recombinant human MMP-9 was expressed in Sf9 insect cells and purified by gelatin-Sepharose affinity chromatography as described previously16,17. It ...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
China Pharmaceutical University
China Pharmaceutical University
Affinity DataIC50: 8.00E+3nMpH: 7.4 T: 2°CAssay Description:TACE was purchased as an active form enzyme (R&D Systems). Hydrolysis of the TACE-substrate Mca-Pro-Leu-Ala-Gln-Ala-Val-Dpa-Arg-Ser-Ser-Ser-Arg-NH (s...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMpH: 7.4 T: 2°CAssay Description:The activity of recombinant human MMP-3 (catalytic domain, Calbiochem) was detected with the substrate Mca-Arg-Pro-Lys-Pro-Val-Glu-Nval-Trp-Arg-Lys(D...More data for this Ligand-Target Pair
Affinity DataIC50: 650nMpH: 7.4 T: 2°CAssay Description:Recombinant human MMP-8 was purchased as an active form enzyme (Sino Biological Inc.). The enzyme activity was detected with the same fluorogenic pep...More data for this Ligand-Target Pair